INVOKAMET XR Strength — DIN 02477424
Active ingredient(s) See footnote 8 : Strength CANAGLIFLOZIN : 150 MG METFORMIN HYDROCHLORIDE : 1000 MG · JANSSEN INC 19 Green Belt Drive Toronto Ontario Canada M3C 1L9 · Tablet (Extended-Release) · wholesale supply in Canada
Health Canada status: CANCELLED PRE MARKET
What is INVOKAMET XR?
INVOKAMET XR Strength contains Active ingredient(s) See footnote 8 : Strength CANAGLIFLOZIN : 150 MG METFORMIN HYDROCHLORIDE : 1000 MG. It is listed in the Health Canada Drug Product Database under DIN 02477424, held by JANSSEN INC 19 Green Belt Drive Toronto Ontario Canada M3C 1L9, supplied as Tablet (Extended-Release) for Oral administration. Health Canada currently lists it as cancelled pre market, status dated 22-Mar-2023. This Drug Identification Number is no longer authorized for sale in Canada, so Nexara does not supply it. The record is kept here because buyers still meet the number on old formularies, purchase orders and tender documents; Nexara can help identify an authorized alternative.
How much does Metformin And Canagliflozin cost around the world?
Metformin And Canagliflozin is listed on 13 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Australia publishes a ex-manufacturer; Austria publishes a KVP (Kassenverkaufspreis); Bahrain publishes a retail (max). Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| United States | acquisition | 6 | 172 | USD███.██ |
| Australia | ex-manufacturer | 33 | 96 | AUD███.██ |
| Czechia | max producer price (ex-factory) | 19 | 96 | CZK███.██ |
| Sweden | AIP (pharmacy purchase price) | 14 | 53 | SEK███.██ |
| Austria | KVP (Kassenverkaufspreis) | 13 | 26 | EUR███.██ |
| Romania | max producer price | 19 | 25 | RON███.██ |
| South Africa | single exit price | 11 | 15 | ZAR███.██ |
| Greece | producer price (ex-factory) | 14 | 14 | EUR███.██ |
| United Kingdom | hospital | 10 | 10 | GBP███.██ |
| Hungary | producer price (ex-factory) | 4 | 5 | HUF███.██ |
| Luxembourg | reimbursement | 5 | 5 | EUR███.██ |
| United Arab Emirates | public | 3 | 3 | AED███.██ |
| Bahrain | retail (max) | 3 | 3 | BHD███.██ |
523 pack listings across 154 brand entries and 12 price bases, refreshed 08 Sep 2026. Ranges span every Metformin And Canagliflozin pack in that market, so a high figure is usually a larger pack rather than the same product.
This table is a regulatory record of where the molecule is listed. The DIN on this page is no longer authorized for sale in Canada, so Nexara does not quote it — see the alternatives above.
Is there a generic Metformin And Canagliflozin in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
2 holders have a Canadian DIN containing Metformin And Canagliflozin, across 10 DINs, of which 3 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| JANSSEN INC | 9 | 3 | INVOKAMET, INVOKAMET XR | Sourceable in Canada |
| JANSSEN INC 19 Green Belt Drive Toronto Ontario Canada M3C 1L9 | 1 | 0 | INVOKAMET XR | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | Strength |
|---|---|
| Dosage form | Tablet (Extended-Release) |
| Route | Oral |
Pack detail is kept as a regulatory record. This DIN is no longer authorized for sale in Canada, so Nexara does not quote this pack.
Substance and classification
| Active substance | Metformin And Canagliflozin |
|---|---|
| ATC code | A10BD16 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02477424 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2477424 |
| Brand name | INVOKAMET XR |
| Generic / active ingredient | Active ingredient(s) See footnote 8 : Strength CANAGLIFLOZIN : 150 MG METFORMIN HYDROCHLORIDE : 1000 MG |
| Market authorization holder | JANSSEN INC 19 Green Belt Drive Toronto Ontario Canada M3C 1L9 |
| Health Canada schedule | PRESCRIPTION |
| ATC code | A10BD16 |
| ATC anatomical main group | A — Alimentary tract and metabolism |
| ATC therapeutic subgroup | A10BD |
| Current status | CANCELLED PRE MARKET |
| Status date | 22-Mar-2023 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
3 of 10 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| INVOKAMET | 50 MG | TABLET | JANSSEN INC | MARKETED | 02455420 |
| INVOKAMET | 50 MG | TABLET | JANSSEN INC | MARKETED | 02455404 |
| INVOKAMET | 1000 MG | TABLET | JANSSEN INC | MARKETED | 02455455 |
| INVOKAMET | 850 MG | TABLET | JANSSEN INC | CANCELLED POST MARKET | 02455447 |
| INVOKAMET | 50 MG | TABLET | JANSSEN INC | CANCELLED POST MARKET | 02455412 |
| INVOKAMET | 500 MG | TABLET | JANSSEN INC | CANCELLED POST MARKET | 02455439 |
| INVOKAMET XR | 500 MG | TABLET (EXTENDED-RELEASE) | JANSSEN INC | CANCELLED PRE MARKET | 02477394 |
| INVOKAMET XR | 1000 MG | TABLET (EXTENDED-RELEASE) | JANSSEN INC | CANCELLED PRE MARKET | 02477408 |
| INVOKAMET XR | 500 MG | TABLET (EXTENDED-RELEASE) | JANSSEN INC | CANCELLED PRE MARKET | 02477416 |
2 · Same class — other molecules in ATC A10BD
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Metformin And Sitagliptin | AG-SITAGLIPTIN HYDROCHLORIDE / METFORMIN · APO-SITAGLIPTIN MALATE / METFORMIN HYDROCHLORIDE · APO-SITAGLIPTIN-METFORMIN · APO-SITAGLIPTIN/METFORMIN XR · +19 more | 63 | 46 | Yes |
| Metformin And Dapagliflozin | APO-DAPAGLIFLOZIN-METFORMIN · AURO-DAPAGLIFLOZIN / METFORMIN · XIGDUO | 6 | 6 | Yes |
| Metformin And Empagliflozin | SYNJARDY | 6 | 6 | Yes |
| Metformin And Canagliflozin | INVOKAMET · INVOKAMET XR | 10 | 3 | Yes |
| Metformin And Alogliptin | KAZANO | 3 | 3 | Yes |
| Metformin And Linagliptin | JENTADUETO | 3 | 3 | Yes |
| Metformin And Rosiglitazone | AVANDAMET · PMS-ROSIGLITAZONE-METFORMIN | 10 | 0 | Not in Canada |
| Combinations Of Oral Blood Glucose Lowering Drugs | SEGLUROMET · STEGLUJAN | 6 | 0 | Not in Canada |
| Pioglitazone And Alogliptin | OSENI | 6 | 0 | Not in Canada |
| Metformin And Saxagliptin | KOMBOGLYZE | 3 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC A10B
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| A10BH | Alogliptin · Linagliptin · Saxagliptin · Sitagliptin | 91 | 63 |
| A10BA | Metformin | 122 | 45 |
| A10BK | Canagliflozin · Dapagliflozin · Empagliflozin · Ertugliflozin | 42 | 30 |
| A10BX | Nateglinide · Repaglinide · Tirzepatide | 54 | 30 |
| A10BB | Acetohexamide · Chlorpropamide · Glibenclamide · Gliclazide · Glimepiride · +1 more | 112 | 23 |
| A10BG | Pioglitazone · Rosiglitazone | 98 | 15 |
| A10BJ | Albiglutide · Dulaglutide · Exenatide · Liraglutide · Lixisenatide · +1 more | 34 | 13 |
| A10BF | Acarbose | 6 | 2 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is INVOKAMET XR called?
The same molecule, Metformin And Canagliflozin, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| Metformin Sandoz | Latin | Australia, Czechia, Sweden |
| METFORMIN VIATRIS | Latin | Czechia |
| Metformin Accord | Latin | Czechia, Sweden |
| Glucophage | Latin | Czechia, South Africa |
| Metformin Orifarm | Latin | Sweden |
| Metformin Teva | Latin | Czechia, Sweden |
| APX-METFORMIN | Latin | Australia |
| BROTMIN | Latin | Czechia |
| Diaformin Viatris | Latin | Australia |
| Glucophage Xr | Latin | Czechia, South Africa |
| METFORMIN MEDREG | Latin | Czechia |
| METFORMIN MYLAN | Latin | Czechia |
| METFORMIN-WGR | Latin | Australia |
| STADAMET | Latin | Czechia |
| STADAMET NEO | Latin | Czechia |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
Can this still be bought in Canada?
No. This Drug Identification Number is cancelled pre market in Health Canada's Drug Product Database, so the product is no longer authorized for sale in Canada and Nexara does not supply it. This page is kept as a regulatory record.
If you are looking for a current equivalent, the alternatives above list every product sharing this therapeutic class, with the marketed ones first. Ask us to source an alternative
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.