HUMALOG MIX 50 (CARTRIDGE) 50 UNIT — DIN 02240297
INSULIN LISPRO PROTAMINE SUSPENSION : 50 UNIT INSULIN LISPRO : 50 UNIT · ELI LILLY CANADA INC · SUSPENSION · wholesale supply in Canada
Health Canada status: MARKETED
What is HUMALOG MIX 50 (CARTRIDGE)?
HUMALOG MIX 50 (CARTRIDGE) 50 UNIT contains INSULIN LISPRO PROTAMINE SUSPENSION : 50 UNIT INSULIN LISPRO : 50 UNIT. It is listed in the Health Canada Drug Product Database under DIN 02240297, held by ELI LILLY CANADA INC, supplied as SUSPENSION for SUBCUTANEOUS administration. Health Canada currently lists it as marketed, status dated 08-Mar-2013. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is HUMALOG MIX 50 (CARTRIDGE) used for?
HUMALOG (insulin lispro injection), HUMALOG MIX25 (25% insulin lispro injection, 75% insulin lispro protamine suspension), and HUMALOG MIX50 (50% insulin lispro injection, 50% insulin lispro protamine suspension) are indicated for the treatment of patients with diabetes mellitus who require insulin for the maintenance of normal glucose homeostasis. HUMALOG insulins are also indicated for the initial stabilization of diabetes mellitus.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How much does Insulin Lispro cost around the world?
Insulin Lispro is listed on 3 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Greece publishes a producer price (ex-factory); Norway publishes a max AUP (pharmacy retail); South Africa publishes a single exit price. Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| Greece | producer price (ex-factory) | 41 | 41 | EUR███.██ |
| Norway | max AUP (pharmacy retail) | 5 | 6 | NOK███.██ |
| South Africa | single exit price | 1 | 2 | ZAR███.██ |
49 pack listings across 47 brand entries and 3 price bases, refreshed 07 Sep 2026. Ranges span every Insulin Lispro pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Insulin Lispro in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
Only one market authorization holder has a Canadian DIN containing Insulin Lispro — 11 DINs, of which 4 are currently marketed. There is no second Canadian source today, so a supply interruption on this holder has no domestic substitute at the same molecule.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| ELI LILLY CANADA INC | 11 | 4 | HUMALOG MIX 25 (CARTRIDGE), HUMALOG MIX 25 (KWIKPEN), HUMALOG MIX 25 (PEN), HUMALOG MIX 50 (CARTRIDGE), HUMALOG MIX 50 (KWIKPEN), +4 more | Sourceable in Canada |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 50 UNIT |
|---|---|
| Dosage form | SUSPENSION |
| Route | SUBCUTANEOUS |
| Pack configuration (monograph) | null |
| Storage | null |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Insulin Lispro |
|---|---|
| ATC code | A10AD04 |
| AHFS class | 68:20.08 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02240297 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2240297 |
| Brand name | HUMALOG MIX 50 (CARTRIDGE) |
| Generic / active ingredient | INSULIN LISPRO PROTAMINE SUSPENSION : 50 UNIT INSULIN LISPRO : 50 UNIT |
| Market authorization holder | ELI LILLY CANADA INC |
| Health Canada schedule | Schedule D |
| ATC code | A10AD04 |
| ATC anatomical main group | A — Alimentary tract and metabolism |
| ATC therapeutic subgroup | A10AD |
| Current status | MARKETED |
| Status date | 08-Mar-2013 |
| Original market date | 2007-01-12 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
4 of 11 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| HUMALOG MIX 25 (CARTRIDGE) | 75 UNIT | SUSPENSION | ELI LILLY CANADA INC | MARKETED | 02240294 |
| HUMALOG MIX 25 (KWIKPEN) | 25 UNIT | SUSPENSION | ELI LILLY CANADA INC | MARKETED | 02403420 |
| HUMALOG MIX 50 (KWIKPEN) | 50 UNIT | SUSPENSION | ELI LILLY CANADA INC | MARKETED | 02403439 |
| HUMALOG MIX 25 (PEN) | 75 UNIT | SUSPENSION | ELI LILLY CANADA INC | CANCELLED POST MARKET | 02240295 |
| LYUMJEV | 300 UNIT / 3 ML | SOLUTION | ELI LILLY CANADA INC | APPROVED | 02520192 |
| LYUMJEV | 100 UNIT | SOLUTION | ELI LILLY CANADA INC | APPROVED | 02520184 |
| LYUMJEV JUNIOR KWIKPEN | 300 UNIT / 3 ML | SOLUTION | ELI LILLY CANADA INC | APPROVED | 02520214 |
| LYUMJEV KWIKPEN | 300 UNIT / 3 ML | SOLUTION | ELI LILLY CANADA INC | APPROVED | 02520206 |
| LYUMJEV KWIKPEN | 600 UNIT / 3 ML | SOLUTION | ELI LILLY CANADA INC | APPROVED | 02520230 |
| LYUMJEV TEMPO PEN | 300 UNIT / 3 ML | SOLUTION | ELI LILLY CANADA INC | APPROVED | 02520222 |
2 · Same class — other molecules in ATC A10AD
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Insulin (Human) | ENTUZITY KWIKPEN · HUMULIN 10/90 CARTRIDGE · HUMULIN 10/90 INJ · HUMULIN 20/80 CARTRIDGE · +14 more | 18 | 4 | Yes |
| Insulin Lispro | HUMALOG MIX 25 (CARTRIDGE) · HUMALOG MIX 25 (KWIKPEN) · HUMALOG MIX 25 (PEN) · HUMALOG MIX 50 (CARTRIDGE) · +5 more | 11 | 4 | Yes |
| Insulin Aspart | NOVOMIX 30 · NOVOMIX 30 (FLEXPEN) | 2 | 1 | Yes |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC A10A
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| A10AB | Insulin (Beef) · Insulin (Human) · Insulin (Pork) · Insulin Aspart · Insulin Glulisine · +1 more | 40 | 24 |
| A10AE | Insulin (Human) · Insulin Degludec · Insulin Degludec And Liraglutide · Insulin Detemir · Insulin Glargine · +2 more | 23 | 15 |
| A10AC | Insulin (Human) · Insulin (Pork) | 13 | 5 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is HUMALOG MIX 50 (CARTRIDGE) called?
The same molecule, Insulin Lispro, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| Actrapid HM (ge) | Latin | South Africa |
| Insuman Rapid | Latin | Norway |
| Humulin NPH | Latin | Norway |
| Humulin NPH KwikPen | Latin | Norway |
| Insuman Infusat | Latin | Norway |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.