NEOSTIGMINE OMEGA 0.5 MG — DIN 02230593
NEOSTIGMINE METHYLSULFATE : 0.5 MG · OMEGA LABORATORIES LIMITED · LIQUID · wholesale supply in Canada
Health Canada status: MARKETED
What is NEOSTIGMINE OMEGA?
NEOSTIGMINE OMEGA 0.5 MG contains NEOSTIGMINE METHYLSULFATE : 0.5 MG. It is listed in the Health Canada Drug Product Database under DIN 02230593, held by OMEGA LABORATORIES LIMITED, supplied as LIQUID for INTRAMUSCULAR ; SUBCUTANEOUS ; INTRAVENOUS administration. Health Canada currently lists it as marketed, status dated 23-Jul-1999. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is NEOSTIGMINE OMEGA used for?
Prophylaxis and treatment of postoperative intestinal atony, urinary retention; in serious cases of myasthenia gravis: to neutralize effect of curare in surgical anesthesia and shock therapy.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How much does Neostigmine cost around the world?
Neostigmine is listed on 4 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Greece publishes a producer price (ex-factory); Morocco publishes a PPV (public price); South Africa publishes a single exit price. Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| United Kingdom | hospital | 2 | 2 | GBP███.██ |
| South Africa | single exit price | 1 | 2 | ZAR███.██ |
| Greece | producer price (ex-factory) | 1 | 1 | EUR███.██ |
| Morocco | PPV (public price) | 1 | 1 | MAD███.██ |
6 pack listings across 5 brand entries and 4 price bases, refreshed 05 Sep 2026. Ranges span every Neostigmine pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Neostigmine in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
11 holders have a Canadian DIN containing Neostigmine, across 26 DINs, of which 6 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| OMEGA LABORATORIES LIMITED | 3 | 3 | NEOSTIGMINE OMEGA | Sourceable in Canada |
| MARCAN PHARMACEUTICALS INC | 2 | 2 | NEOSTIGMINE METHYLSULFATE INJECTION USP | Sourceable in Canada |
| JAMP PHARMA CORPORATION | 1 | 1 | NEOSTIGMINE METHYLSULFATE INJECTION, USP | Sourceable in Canada |
| SANDOZ CANADA INCORPORATED | 5 | 0 | NEOSTIGMINE METHYLSULFATE INJECTION SDZ, NEOSTIGMINE METHYLSULFATE INJECTION USP | No marketed DIN |
| ICN CANADA LTD. | 3 | 0 | PROSTIGMIN INJ 1:1000 USP, PROSTIGMIN INJ 1:2000 USP, PROSTIGMIN INJ 1:400 USP | No marketed DIN |
| JUNO PHARMACEUTICALS CORP. | 3 | 0 | NEOSTIGMINE METHYLSULFATE INJECTION, USP | No marketed DIN |
| DAVID BULL LABORATORIES (PTY) LTD. | 2 | 0 | NEOSTIGMINE METHYLSULFATE INJ 0.5MG/ML USP, NEOSTIGMINE METHYLSULFATE INJ 1MG/ML USP | No marketed DIN |
| FRESENIUS KABI CANADA LTD | 2 | 0 | NEOSTIGMINE METHYLSULFATE INJECTION | No marketed DIN |
| PHARMASCIENCE INC | 2 | 0 | PMS-NEOSTIGMINE METHYLSULFATE INJ 0.5MG/ML, PMS-NEOSTIGMINE METHYLSULFATE INJ 1MG/ML | No marketed DIN |
| STERIMAX INC | 2 | 0 | NEOSTIGMINE METHYLSULFATE INJECTION USP | No marketed DIN |
| BAUSCH HEALTH, CANADA INC. | 1 | 0 | PROSTIGMIN | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 0.5 MG |
|---|---|
| Dosage form | LIQUID |
| Route | INTRAMUSCULAR ; SUBCUTANEOUS ; INTRAVENOUS |
| Pack configuration (monograph) | 0.5 mg/mL: multidose vials of 1 mL and 10 mL, boxes of 10. 1 mg/mL: multidose vials of 10 mL, boxes of 10. 2.5 mg/mL: multidose vials of 5 mL, boxes of 10. |
| Storage | Store between 15 and 30°C. Protect from light. Multiple use. Discard 28 days after initial use. |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Neostigmine |
|---|---|
| ATC code | N07AA01 |
| AHFS class | 12:04.00 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02230593 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2230593 |
| Brand name | NEOSTIGMINE OMEGA |
| Generic / active ingredient | NEOSTIGMINE METHYLSULFATE : 0.5 MG |
| Market authorization holder | OMEGA LABORATORIES LIMITED |
| Health Canada schedule | Prescription |
| ATC code | N07AA01 |
| ATC anatomical main group | N — Nervous system |
| ATC therapeutic subgroup | N07AA |
| Current status | MARKETED |
| Status date | 23-Jul-1999 |
| Original market date | 1999-05-28 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
6 of 26 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| NEOSTIGMINE METHYLSULFATE INJECTION USP | 1 MG | SOLUTION | MARCAN PHARMACEUTICALS INC | MARKETED | 02475499 |
| NEOSTIGMINE METHYLSULFATE INJECTION USP | 0.5 MG | SOLUTION | MARCAN PHARMACEUTICALS INC | MARKETED | 02475480 |
| NEOSTIGMINE METHYLSULFATE INJECTION, USP | 0.5 MG | SOLUTION | JAMP PHARMA CORPORATION | MARKETED | 02537516 |
| NEOSTIGMINE OMEGA | 2.5 MG | SOLUTION | OMEGA LABORATORIES LIMITED | MARKETED | 02387166 |
| NEOSTIGMINE OMEGA | 1 MG | LIQUID | OMEGA LABORATORIES LIMITED | MARKETED | 02230592 |
| NEOSTIGMINE METHYLSULFATE INJ 0.5MG/ML USP | .5 MG | LIQUID | DAVID BULL LABORATORIES (PTY) LTD. | CANCELLED POST MARKET | 01904183 |
| NEOSTIGMINE METHYLSULFATE INJ 1MG/ML USP | 1 MG | LIQUID | DAVID BULL LABORATORIES (PTY) LTD. | CANCELLED POST MARKET | 01914588 |
| NEOSTIGMINE METHYLSULFATE INJECTION | 0.5 MG | LIQUID | FRESENIUS KABI CANADA LTD | CANCELLED PRE MARKET | 02243104 |
| NEOSTIGMINE METHYLSULFATE INJECTION | 1 MG | LIQUID | FRESENIUS KABI CANADA LTD | CANCELLED PRE MARKET | 02243103 |
| NEOSTIGMINE METHYLSULFATE INJECTION SDZ | 2.5 MG | SOLUTION | SANDOZ CANADA INCORPORATED | CANCELLED PRE MARKET | 02385228 |
2 · Same class — other molecules in ATC N07AA
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Neostigmine | NEOSTIGMINE METHYLSULFATE INJ 0.5MG/ML USP · NEOSTIGMINE METHYLSULFATE INJ 1MG/ML USP · NEOSTIGMINE METHYLSULFATE INJECTION · NEOSTIGMINE METHYLSULFATE INJECTION SDZ · +9 more | 26 | 6 | Yes |
| Pyridostigmine | JAMP PYRIDOSTIGMINE BROMIDE · MESTINON · MESTINON-SR · REGONOL INJ 5MG/ML · +1 more | 5 | 4 | Yes |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC N07A
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| N07AX | Pilocarpine | 5 | 3 |
| N07AB | Bethanechol · Carbachol | 17 | 2 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is NEOSTIGMINE OMEGA called?
The same molecule, Neostigmine, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| Micro-Neostigmine | Latin | South Africa |
| PROSTIGMINE | Latin | Morocco |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.