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ESTRING 2 MG

ESTRADIOL : 2 MG · DIN 02168898 · PFIZER CANADA ULC

Health Canada status: MARKETED

What is ESTRING?

ESTRING 2 MG contains ESTRADIOL : 2 MG. It is listed in the Health Canada Drug Product Database under DIN 02168898, held by PFIZER CANADA ULC, supplied as RING (SLOW-RELEASE) for VAGINAL administration. Health Canada currently lists it as marketed, status dated 13-Apr-2006. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.

What is ESTRING used for?

ESTRING (17 β - estradiol) is indicated for postmenopausal urogenital complaints due to estrogen deficiency such as feeling of dryness in the vagina (atrophic vaginitis) with or without pruritus vulvae, dyspareunia, dysuria and urinary urgency (atrophic muco sa in the urethra and trigonum). ESTRING should be prescribed with an appropriate dosage of a progestin for women with intact uteri, in order to prevent endometrial hyperplasia/carcinoma. The maximum recommended duration of continuous therapy is 2 years.

Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.

Product details and regulatory record

DIN02168898
Brand nameESTRING
Generic / active ingredientESTRADIOL : 2 MG
ManufacturerPFIZER CANADA ULC
Strength2 MG
Dosage formRING (SLOW-RELEASE)
Route of administrationVAGINAL
SchedulePrescription
ATC codeG03CA03 ESTRADIOL
BiosimilarNo
Health Canada statusMARKETED
Status date13-Apr-2006

How is it stored and handled?

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How is it supplied?

One ring is individually packed in a heat-sealed rectangular pouch consisting of, from outside to inside: Polyester/aluminum foil/low density polyethylene. The pouch is provided with a tear-off notch on one side. Each pouch is packed into a cardboard carton containing a Patient Information Leaflet.

What can be used instead?

Other Canadian products sharing ATC code G03CA03 ESTRADIOL. 22 of 51 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.

ProductStrengthFormManufacturerHealth Canada statusDIN
CLIMARA 2525 MCG / 24 HOURPATCHBAYER INCMARKETEDDIN 02247499
CLIMARA 5050 MCG / 24 HOURPATCHBAYER INCMARKETEDDIN 02231509
CLIMARA 7575 MCG / 24 HOURPATCHBAYER INCMARKETEDDIN 02247500
DIVIGEL0.1 %GELSEARCHLIGHT PHARMA INCMARKETEDDIN 02424924
DIVIGEL0.1 %GELSEARCHLIGHT PHARMA INCMARKETEDDIN 02424835
DIVIGEL0.1 %GELSEARCHLIGHT PHARMA INCMARKETEDDIN 02424843
ESTRADOT 100100 MCG / 24 HOURPATCHSANDOZ CANADA INCORPORATEDMARKETEDDIN 02244002
ESTRADOT 2525 MCG / 24 HOURPATCHSANDOZ CANADA INCORPORATEDMARKETEDDIN 02245676
ESTRADOT 37.537.5 MCG / 24 HOURPATCHSANDOZ CANADA INCORPORATEDMARKETEDDIN 02243999
ESTRADOT 5050 MCG / 24 HOURPATCHSANDOZ CANADA INCORPORATEDMARKETEDDIN 02244000

Who else supplies ESTRADIOL worldwide?

Nexara tracks national medicine registries and published price lists across multiple markets. ESTRADIOL appears in 211 registered pack listings across 14 markets, published on 11 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.

Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.

How can I get it?

Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.

Request a quote for ESTRING

Ordering questions

Who can buy this from Nexara?

Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.

Is there a minimum order?

Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.

What is the lead time?

Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.

Can Nexara supply this for a clinical trial?

Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.

Health Canada Drug Product Database (DPD), DIN 02168898. Last reviewed 2026-09-09. Nexara Health is a licensed wholesaler and supplies licensed entities only; consumer orders are routed to a partner pharmacy.