IOPIDINE 1 %
APRACLONIDINE (APRACLONIDINE HYDROCHLORIDE) : 1 % · DIN 00888354 · ESSENTIAL PHARMA SWITZERLAND GMBH
Health Canada status: MARKETED
What is IOPIDINE?
IOPIDINE 1 % contains APRACLONIDINE (APRACLONIDINE HYDROCHLORIDE) : 1 %. It is listed in the Health Canada Drug Product Database under DIN 00888354, held by ESSENTIAL PHARMA SWITZERLAND GMBH, supplied as SOLUTION for OPHTHALMIC administration. Health Canada currently lists it as marketed, status dated 19-May-2023. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is IOPIDINE used for?
IOPIDINE 1% (apraclonidine ophthalmic solution) is indicated for the control or prevention of postsurgical elevations in intraocular pressure (IOP) that occur in patients after anterior segment laser ophthalmic surgery including argon laser trabeculoplasty, argon laser iridotomy and neodymium:yttrium aluminum garnet (Nd:YAG) laser posterior capsulotomy. IOPIDINE 0.5% (apraclonidine ophthalmic solution) is indicated for adjunctive use in lowering intraocular pressure (IOP) and may be used as a short-term therapy in glaucoma patients on maximally tolerated medical therapy who require an additional IOP reduction.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
Product details and regulatory record
| DIN | 00888354 |
|---|---|
| Brand name | IOPIDINE |
| Generic / active ingredient | APRACLONIDINE (APRACLONIDINE HYDROCHLORIDE) : 1 % |
| Manufacturer | ESSENTIAL PHARMA SWITZERLAND GMBH |
| Strength | 1 % |
| Dosage form | SOLUTION |
| Route of administration | OPHTHALMIC |
| Schedule | Prescription |
| ATC code | S01EA03 APRACLONIDINE |
| AHFS class | 52:92.00 |
| Biosimilar | No |
| Health Canada status | MARKETED |
| Status date | 19-May-2023 |
| Original market date | 1992-12-31 00:00:00 |
How is it stored and handled?
Store between 2-30 °C (36 – 86 °F). Do not freeze. Protect from light. Keep out of the reach and sight of children.
How is it supplied?
IOPIDINE 1% is supplied as: 0.1 mL in plastic ophthalmic dispensers, packaged two per pouch. IOPIDINE 0.5% is supplied in a 5 mL plastic DROP-TAINER® dispenser.
What can be used instead?
Other Canadian products sharing ATC code S01EA03 APRACLONIDINE. 2 of 2 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.
| Product | Strength | Form | Manufacturer | Health Canada status | DIN |
|---|---|---|---|---|---|
| IOPIDINE | 0.5 % | SOLUTION | ESSENTIAL PHARMA SWITZERLAND GMBH | MARKETED | DIN 02076306 |
Who else supplies APRACLONIDINE worldwide?
Nexara tracks national medicine registries and published price lists across multiple markets. APRACLONIDINE appears in 8 registered pack listings across 6 markets, published on 6 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.
Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.