APO-AZELASTINE/FLUTICASONE 137 MCG — DIN 02540886
AZELASTINE HYDROCHLORIDE : 137 MCG FLUTICASONE PROPIONATE : 50 MCG · APOTEX INC · SPRAY, METERED DOSE · wholesale supply in Canada
Health Canada status: MARKETED
What is APO-AZELASTINE/FLUTICASONE?
APO-AZELASTINE/FLUTICASONE 137 MCG contains AZELASTINE HYDROCHLORIDE : 137 MCG FLUTICASONE PROPIONATE : 50 MCG. It is listed in the Health Canada Drug Product Database under DIN 02540886, held by APOTEX INC, supplied as SPRAY, METERED DOSE for NASAL administration. Health Canada currently lists it as marketed, status dated 31-Oct-2023. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is APO-AZELASTINE/FLUTICASONE used for?
APO-AZELASTINE/FLUTICASONE (azelastine hydrochloride and fluticasone propionate suspension nasal spray) is indicated for: • the symptomatic treatment of moderate to severe seasonal allergic rhinitis (SAR) and associated ocular symptoms in adults, adolescents, and children aged 6 years and older.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
Is there a generic Fluticasone, Combinations in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
3 holders have a Canadian DIN containing Fluticasone, Combinations, across 3 DINs, of which 3 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| APOTEX INC | 1 | 1 | APO-AZELASTINE/FLUTICASONE | Sourceable in Canada |
| BGP PHARMA ULC | 1 | 1 | DYMISTA | Sourceable in Canada |
| MYLAN PHARMACEUTICALS ULC | 1 | 1 | MYLAN-AZELASTINE/FLUTICASONE | Sourceable in Canada |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 137 MCG |
|---|---|
| Dosage form | SPRAY, METERED DOSE |
| Route | NASAL |
| Pack configuration (monograph) | 25 mL amber glass vials containing 23.0 g of drug product and at least 120 actuations |
| Storage | null |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Fluticasone, Combinations |
|---|---|
| ATC code | R01AD58 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02540886 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2540886 |
| Brand name | APO-AZELASTINE/FLUTICASONE |
| Generic / active ingredient | AZELASTINE HYDROCHLORIDE : 137 MCG FLUTICASONE PROPIONATE : 50 MCG |
| Market authorization holder | APOTEX INC |
| Health Canada schedule | Prescription |
| ATC code | R01AD58 |
| ATC anatomical main group | R — Respiratory system |
| ATC therapeutic subgroup | R01AD |
| Current status | MARKETED |
| Status date | 31-Oct-2023 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
3 of 3 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| DYMISTA | 50 MCG | SPRAY, METERED DOSE | BGP PHARMA ULC | MARKETED | 02432889 |
| MYLAN-AZELASTINE/FLUTICASONE | 137 MCG | SPRAY, METERED DOSE | MYLAN PHARMACEUTICALS ULC | MARKETED | 02530341 |
2 · Same class — other molecules in ATC R01AD
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Mometasone | APO-MOMETASONE · MOMETASONE · MOSASPRAY · NASAL ALLERGY AND CONGESTION RELIEF · +4 more | 9 | 6 | Yes |
| Fluticasone | 24HR NASAL ALLERGY RELIEF · ALLERGY RELIEF NASAL SPRAY · APO-FLUTICASONE · FLONASE - AEM-SUS NAS 50MCG/MD · +5 more | 9 | 4 | Yes |
| Budesonide | MYLAN-BUDESONIDE AQ · RHINOCORT AQUA · RHINOCORT AQUA 100MCG · RHINOCORT TURBUHALER 100 MCG/DOSE | 5 | 3 | Yes |
| Triamcinolone | APO-TRIAMCINOLONE AQ · NASACORT · NASACORT ALLERGY 24HR · NASACORT AQ · +1 more | 5 | 3 | Yes |
| Fluticasone, Combinations | APO-AZELASTINE/FLUTICASONE · DYMISTA · MYLAN-AZELASTINE/FLUTICASONE | 3 | 3 | Yes |
| Beclomethasone | APO-BECLOMETHASONE NASAL SPRAY · BECLOMETHASONE AQUEOUS NASAL SPRAY 50MCG/METERED DOSE · BECLOMETHASONE DIPROPIONATE NAS-SPR 50MCG/AEM · BECLOMETHASONE DIPROPIONATE NASAL INHALER · +8 more | 13 | 2 | Yes |
| Ciclesonide | APO-CICLESONIDE · OMNARIS · OMNARIS HFA | 3 | 1 | Yes |
| Fluticasone Furoate | AVAMYS | 1 | 1 | Yes |
| Mometasone, Combinations | RYALTRIS | 1 | 1 | Yes |
| Flunisolide | APO-FLUNISOLIDE NASAL SPRAY · NOVO-FLUNISOLIDE · PMS-FLUNISOLIDE · RATIO-FLUNISOLIDE · +2 more | 6 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC R01A
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| R01AA | Ephedrine · Oxymetazoline · Phenylephrine · Xylometazoline | 76 | 18 |
| R01AX | Combinations · Ipratropium Bromide · Various | 42 | 4 |
| R01AB | Ephedrine · Naphazoline · Oxymetazoline · Phenylephrine | 12 | 1 |
| R01AC | Cromoglicic Acid · Levocabastine | 6 | 0 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.