CAPECITABINE 500 MG — DIN 02514990
CAPECITABINE : 500 MG · SANIS HEALTH INC · TABLET · wholesale supply in Canada
Health Canada status: MARKETED
What is CAPECITABINE?
CAPECITABINE 500 MG contains CAPECITABINE : 500 MG. It is listed in the Health Canada Drug Product Database under DIN 02514990, held by SANIS HEALTH INC, supplied as TABLET for ORAL administration. Health Canada currently lists it as marketed, status dated 22-Oct-2021. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is CAPECITABINE used for?
Adjuvant treatment of stage III colon cancer; first-line metastatic colorectal cancer; metastatic colorectal cancer with oxaliplatin; advanced/metastatic breast cancer (mono or with docetaxel).
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How much does Capecitabine cost around the world?
Capecitabine is listed on 10 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Australia publishes a ex-manufacturer; Bahrain publishes a retail (max); Greece publishes a producer price (ex-factory). Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| United States | acquisition | 2 | 28 | USD███.██ |
| South Africa | single exit price | 16 | 16 | ZAR███.██ |
| Saudi Arabia | public | 12 | 15 | SAR███.██ |
| Greece | producer price (ex-factory) | 10 | 10 | EUR███.██ |
| Bahrain | retail (max) | 5 | 8 | BHD███.██ |
| Hungary | producer price (ex-factory) | 6 | 8 | HUF███.██ |
| United Arab Emirates | public | 4 | 4 | AED███.██ |
| United Kingdom | hospital | 3 | 3 | GBP███.██ |
| Australia | ex-manufacturer | 1 | 1 | AUD███.██ |
| Morocco | PPV (public price) | 1 | 1 | MAD███.██ |
94 pack listings across 60 brand entries and 8 price bases, refreshed 08 Sep 2026. Ranges span every Capecitabine pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Capecitabine in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
10 holders have a Canadian DIN containing Capecitabine, across 20 DINs, of which 11 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| ACCORD HEALTHCARE INC | 2 | 2 | ACH-CAPECITABINE | Sourceable in Canada |
| JAMP PHARMA CORPORATION | 2 | 2 | CAPECITABINE | Sourceable in Canada |
| SANDOZ CANADA INCORPORATED | 2 | 2 | SANDOZ CAPECITABINE | Sourceable in Canada |
| SANIS HEALTH INC | 2 | 2 | CAPECITABINE | Sourceable in Canada |
| TARO PHARMACEUTICALS INC | 2 | 2 | TARO-CAPECITABINE | Sourceable in Canada |
| MINT PHARMACEUTICALS INC | 2 | 1 | MINT-CAPECITABINE | Sourceable in Canada |
| APOTEX INC | 2 | 0 | APO-CAPECITABINE | No marketed DIN |
| CHEPLAPHARM ARZNEIMITTEL GMBH | 2 | 0 | XELODA | No marketed DIN |
| SIVEM PHARMACEUTICALS ULC | 2 | 0 | CAPECITABINE | No marketed DIN |
| TEVA CANADA LIMITED | 2 | 0 | TEVA-CAPECITABINE | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 500 MG |
|---|---|
| Dosage form | TABLET |
| Route | ORAL |
| Pack configuration (monograph) | 150 mg: HDPE bottles of 60, blister packs of 60. 500 mg: HDPE bottles of 120, blister packs of 120. |
| Storage | Not explicitly detailed in provided text snippet (standard section 11 mentioned in TOC but content not in excerpt). |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation, because this listing covers more than one of them.
Substance and classification
| Active substance | Capecitabine |
|---|---|
| ATC code | L01BC06 |
| AHFS class | 10:00.00 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02514990 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2514990 |
| Brand name | CAPECITABINE |
| Generic / active ingredient | CAPECITABINE : 500 MG |
| Market authorization holder | SANIS HEALTH INC |
| Health Canada schedule | Prescription |
| ATC code | L01BC06 |
| ATC anatomical main group | L — Antineoplastic and immunomodulating agents |
| ATC therapeutic subgroup | L01BC |
| Current status | MARKETED |
| Status date | 22-Oct-2021 |
| Original market date | 2021-10-22 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
How is it administered?
1250 mg/m2 twice daily for 14 days followed by 7-day rest. In combination with oxaliplatin: 1000 mg/m2 twice daily. Swallow whole with water within 30 mins after a meal. Do not crush or cut.
Included because it drives pack selection and wastage. Consult the monograph.
Contraindications
Hypersensitivity to capecitabine or 5-fluorouracil; severe renal impairment (CrCl <30 mL/min); complete absence of DPD activity; concomitant use with sorivudine or brivudine.
Warnings and precautions
Serious: Acute renal failure from dehydration; cardiotoxicity (sudden death); severe skin reactions (SJS/TEN, hand-foot syndrome); DPD deficiency toxicity; interaction with coumarin anticoagulants.
Is Capecitabine in shortage in Canada?
A Canadian shortage report is on file for a product containing this molecule: Anticipated — reported by SANIS HEALTH INC, last seen 04 Sep 2026. A shortage on one presentation does not always affect every DIN of the molecule — the alternatives below list what else is marketed in Canada. Nexara can confirm current availability and identify substitutions or import options where permitted.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
11 of 20 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| ACH-CAPECITABINE | 150 MG | TABLET | ACCORD HEALTHCARE INC | MARKETED | 02426757 |
| ACH-CAPECITABINE | 500 MG | TABLET | ACCORD HEALTHCARE INC | MARKETED | 02426765 |
| CAPECITABINE | 500 MG | TABLET | JAMP PHARMA CORPORATION | MARKETED | 02519887 |
| CAPECITABINE | 150 MG | TABLET | JAMP PHARMA CORPORATION | MARKETED | 02519879 |
| CAPECITABINE | 150 MG | TABLET | SANIS HEALTH INC | MARKETED | 02514982 |
| MINT-CAPECITABINE | 500 MG | TABLET | MINT PHARMACEUTICALS INC | MARKETED | 02508028 |
| SANDOZ CAPECITABINE | 500 MG | TABLET | SANDOZ CANADA INCORPORATED | MARKETED | 02421925 |
| SANDOZ CAPECITABINE | 150 MG | TABLET | SANDOZ CANADA INCORPORATED | MARKETED | 02421917 |
| TARO-CAPECITABINE | 150 MG | TABLET | TARO PHARMACEUTICALS INC | MARKETED | 02457490 |
| TARO-CAPECITABINE | 500 MG | TABLET | TARO PHARMACEUTICALS INC | MARKETED | 02457504 |
2 · Same class — other molecules in ATC L01BC
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Capecitabine | ACH-CAPECITABINE · APO-CAPECITABINE · CAPECITABINE · MINT-CAPECITABINE · +4 more | 20 | 11 | Yes |
| Azacitidine | AZACITIDINE FOR INJECTION · NAT-AZACITIDINE · ONUREG · PMS-AZACITIDINE FOR INJECTION · +2 more | 14 | 7 | Yes |
| Fluorouracil | ADRUCIL · ADRUCIL INJ 50MG/ML · EFUDEX · FLUOROPLEX CREAM 1% · +4 more | 15 | 6 | Yes |
| Cytarabine | AJ-CYTARABINE · CYTARABINE - PWS 1GN/VIAL · CYTARABINE - PWS 2GM/VIAL · CYTARABINE - PWS 500MG/VIAL · +8 more | 19 | 3 | Yes |
| Gemcitabine | ACT GEMCITABINE · AJ-GEMCITABINE · GEMCITABINE FOR INJECTION · GEMCITABINE FOR INJECTION CONCENTRATE · +7 more | 38 | 2 | Yes |
| Trifluridine, Combinations | LONSURF | 2 | 2 | Yes |
| Decitabine | DACOGEN · DEMYLOCAN | 2 | 1 | Yes |
| Fluorouracil, Combinations | ACTIKERALL | 1 | 1 | Yes |
| Decitabine, Combinations | INQOVI | 1 | 1 | Yes |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC L01B
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| L01BA | Methotrexate · Pemetrexed · Pralatrexate% · Raltitrexed | 90 | 36 |
| L01BB | Cladribine · Clofarabine · Fludarabine · Mercaptopurine · Nelarabine · +1 more | 18 | 10 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is CAPECITABINE called?
Also recorded in Canada as: capecitabine 150 MG Oral Tablet [Xeloda] (US), capecitabine 500 MG Oral Tablet [Xeloda] (US), capecitabine 150 MG Oral Tablet (US), capecitabine 500 MG Oral Tablet (US), CAPECITABINE 150MG (US), CAPECITABINE 500MG (US), CAPECITABINE TABLETS, 150 MG (US), CAPECITABINE TABLETS, 500 MG (US), Xeloda (GLOBAL), Xeloda (US), Xeloda (EU), Xeloda (IN), Capegard (IN), Capnat (IN), Capecit-Bin (IN).
The same molecule, Capecitabine, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| CAPECITABINE KOANAA | Latin | Bahrain |
| Catabina | Latin | Saudi Arabia |
| KAPETRAL | Latin | Bahrain |
| Pitacro | Latin | Saudi Arabia |
| RELICITABINE | Latin | Bahrain |
| Xelobine | Latin | Saudi Arabia |
| Capecitabine NEAPOLIS | Latin | Saudi Arabia |
| CAPECITABINE SPC | Latin | Bahrain |
| Emcap | Latin | Saudi Arabia |
| Xelabine | Latin | Australia |
| XELODA | Latin | Morocco |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.