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Comfortan 10 mg Solution is a Health Canada–registered veterinary drug (DIN 02496658) held by Eurovet Animal Health B.v., containing Methadone Hydrochloride. Health Canada lists its status as Marketed (status date 05 Nov 2020). Nexara Health has matched 226 registrations of Methadone Hydrochloride across 16 other regulated markets.

Health Canada registration

DIN02496658
Brand nameComfortan
Active ingredientMethadone Hydrochloride
Strength10 mg
Dosage formSolution
RouteIntramuscular
CompanyEurovet Animal Health B.v.
StatusMarketed — 05 Nov 2020
ClassVeterinary
ATC
AHFS
Regulator recordHealth Canada DPD entry · Product monograph

Methadone Hydrochloride registered in other markets

226 registrations of the same molecule in 16 national registries outside Canada (first 81 shown, exact strength and form first). Each row is taken from the regulator's own published list; status is shown as the registry reports it.

CountryProductMarketing authorisation holderStrengthFormStatusRegistry
AustraliaAspen Methadone SyrupAsOral liquid containing methadone hydrochloride 25 mg per 5 mL in 200 mL bottle, 1 mLCAPBS
AustraliaAspen Methadone SyrupAsOral liquid containing methadone hydrochloride 25 mg per 5 mL in 1 L bottle, 1 mLCAPBS
AustraliaAspen Methadone SyrupAsOral liquid containing methadone hydrochloride 25 mg per 5 mL in 200 mL bottle, 1 mLPLPBS
AustraliaAspen Methadone SyrupAsOral liquid containing methadone hydrochloride 25 mg per 5 mL in 200 mL bottle, 1 mLPLPBS
AustraliaMethadone-AftAeTablet containing methadone hydrochloride 5 mgPLPBS
AustraliaMethadone-AftAeTablet containing methadone hydrochloride 5 mgGEPBS
AustraliaPhyseptoneAsInjection containing methadone hydrochloride 10 mg in 1 mLGEPBS
AustraliaPhyseptoneAsTablet containing methadone hydrochloride 10 mgGEPBS
AustriaMethasan 10 mg Tabl.—28Styellow boxeEKO (Erstattungskodex)
AustriaMethasan 10 mg Tabl.—7Styellow boxeEKO (Erstattungskodex)
AustriaMethasan 10 mg/ml Konz. zur Herst. einer Lsg. zum Einnehmen—150mlyellow boxeEKO (Erstattungskodex)
AustriaMethasan 10 mg/ml Konz. zur Herst. einer Lsg. zum Einnehmen—100mlyellow boxeEKO (Erstattungskodex)
AustriaMethasan 10 mg/ml Konz. zur Herst. einer Lsg. zum Einnehmen—300mlyellow boxeEKO (Erstattungskodex)
AustriaMethasan 20 mg Tabl.—7Styellow boxeEKO (Erstattungskodex)
AustriaMethasan 20 mg Tabl.—28Styellow boxeEKO (Erstattungskodex)
AustriaMethasan 40 mg Tabl.—7Styellow boxeEKO (Erstattungskodex)
BulgariaMetadon AlkaloidАлкалоид ЕООД10 mg/ml oral solutionперорален разтворПо лекарско предписаниеBDA
BulgariaMethadone SopharmaСофарма АД10 mg/ml oral solutionперорален разтворПо лекарско предписаниеBDA
BulgariaMethasanG.L. Pharma GmbH10 mg/ml concentrate for oral solutionперорален разтворПо лекарско предписаниеBDA
Czech RepublicMetadon Alkaloid—10MG/MLPor Gtt SolFSUKL DLP
Czech RepublicMisyo—10MG/MLPor Cnc SolRSUKL DLP
Czech RepublicSublana—10MG/MLPor Cnc SolRSUKL DLP
Hong KongMethadone Linctus 80mg/20ml (New Formula)Drug Procurement & Clinic Service Division Of The Drug Office, Department Of HealthRegisteredDH Drug Office
Hong KongMethadone Tab BP 5 mgTeva Pharmaceutical Hong Kong O/B Teva Pharmaceutical Hong Kong LimitedRegisteredDH Drug Office
HungaryMetadon EP 10 mg TablettaExtractumPharma Gyógyszergyártó, Forgalmazó és Szaktanácsadó Zártkörűen működő részvénytársaság50x hdpe tartályban + gyermekbiztos hdpe kupakNEAK PUPHA
HungaryMetadon EP 10 mg TablettaExtractumPharma Gyógyszergyártó, Forgalmazó és Szaktanácsadó Zártkörűen működő részvénytársaság90x hdpe tartályban + gyermekbiztos hdpe kupakNEAK PUPHA
HungaryMetadon EP 5 mg TablettaExtractumPharma Gyógyszergyártó, Forgalmazó és Szaktanácsadó Zártkörűen működő részvénytársaság50x hdpe tartályban + gyermekbiztos hdpe kupakNEAK PUPHA
HungaryMetadon EP 5 mg TablettaExtractumPharma Gyógyszergyártó, Forgalmazó és Szaktanácsadó Zártkörűen működő részvénytársaság10x hdpe tartályban + gyermekbiztos hdpe kupakNEAK PUPHA
HungaryMisyo 10 mg/mL Koncentrátum Belsőleges OldathozINN-FARM d.o.o.1x1000ml üvegbenNEAK PUPHA
IcelandInsistorIcepharma - óskráð10 mg/mlstl0Lyfjastofnun lyfjaverdskra
IcelandSynthadon vet.Le Vet Beheer B.V.10 mg/mlstl0Lyfjastofnun lyfjaverdskra
IrelandMethadone hydrochloride 1 mg/ml oral solutionAlkaloid - INT d.o.oOral solutionNot marketedHPRA
IrelandMethadone Hydrochloride 5 mg tabletsAscot Laboratories (Ireland) LimitedTabletNot marketedHPRA
IrelandMethadone Hydrochloride Sugar Free 1 mg/1 ml Oral SolutionTaw Pharma (Ireland) LimitedOral solutionMarketedHPRA
IrelandMethadone Mixture DTF (Sugar Free) 1 mg in 1 ml Oral SolutionEthypharmOral solutionMarketedHPRA
IrelandPhymet DTF 1 mg/ml SyrupGlaxoSmithKline (Ireland) LimitedSyrupNot marketedHPRA
IrelandPinadone 1 mg/ml Oral SolutionPinewood Laboratories LimitedOral solutionMarketedHPRA
MalaysiaAlphadone Syrup 10mg/mlRoyce Pharma Manufacturing Sdn. Bhd.PrescriptionPRODUCT APPROVEDNPRA
MalaysiaAlphadone Syrup 5mg/mlRoyce Pharma Manufacturing Sdn. Bhd.PrescriptionPRODUCT APPROVEDNPRA
MalaysiaMethadyne Injection 10mg/mlPets Corner Sdn BhdVeterinaryPRODUCT APPROVEDNPRA
MaltaMetasedin 5mg tabletsCentral Procurement & Supplies UnitTabletAuthorisedMedicines Authority
NetherlandsEptadone Drank Suikervrij 10 mg/mlL. Molteni & C. dei F.LLi Alitti Soceità di Esercizio S.p.A.DrankUitsluitend receptEU national register
NetherlandsEptadone Drank Suikervrij 5 mg/mlL. Molteni & C. dei F.LLi Alitti Soceità di Esercizio S.p.A.DrankUitsluitend receptEU national register
NetherlandsMethadon HCl Aurobindo 10 mg, tablettenAurobindo Pharma B.V.TabletUitsluitend receptEU national register
NetherlandsMethadon HCl Aurobindo 10 mg, tablettenAurobindo Pharma B.V.TabletUitsluitend receptEU national register
NetherlandsMethadon HCl Aurobindo 20 mg, tablettenAurobindo Pharma B.V.TabletUitsluitend receptEU national register
NetherlandsMethadon HCl Aurobindo 20 mg, tablettenAurobindo Pharma B.V.TabletUitsluitend receptEU national register
NetherlandsMethadon HCl Aurobindo 40 mg, tablettenAurobindo Pharma B.V.TabletUitsluitend receptEU national register
NetherlandsMethadon HCl Aurobindo 40 mg, tablettenAurobindo Pharma B.V.TabletUitsluitend receptEU national register
Saudi ArabiaMETHADONE MARTINDALE PHARMA 2 mg/ml oral solution—2InactiveSFDA
Saudi ArabiaMETHADONE MARTINDALE PHARMA 2 mg/ml oral solution—2InactiveSFDA
South AfricaEquity MethadoneEquity Pharmaceuticals (Pty) Ltd2 mg/mlSyrS6DoH SEP database
South AfricaEquity MethadoneEquity Pharmaceuticals (Pty) Ltd2 mg/mlSyrS6DoH SEP database
South AfricaMethadone Adco 10mgAdcock Ingram Critical Care (Pty) Ltd10 mg/mlSolS6DoH SEP database
South AfricaMethadone Adco 10mgAdcock Ingram Critical Care (Pty) Ltd10 mg/mlSolS6DoH SEP database
South AfricaMisyo 10 mg/mlUmsebe Healthcare10 mg/mlSolS6DoH SEP database
South AfricaMisyo 10 mg/mlUmsebe Healthcare10 mg/mlSolS6DoH SEP database
South AfricaPhyseptonePharmacare Limited, Woodmead2 mg/5mlSusS6DoH SEP database
South AfricaRutrexArya Pharma (Pty) Ltd10 mg/mlSolS6DoH SEP database
Taiwan”Molteni”Methadone Hydrochloride 5 mg/ml Oral SolutionL. Molteni & C. Dei F. Lli Alitti Societa Di Esercizio S.p.a.口服液劑已註銷TFDA
Taiwan“PPCD”Methadone Oral Concentrate 10mg/mL衛生福利部食品藥物管理署管制藥品製藥工廠內服液劑RegisteredTFDA
TaiwanMethadone HCLPioneer Agro Industries Sanvin Laboratories Private Limited(粉)RegisteredTFDA
TaiwanMethadone HydrochlorideRusan Pharma Ltd.(粉)RegisteredTFDA
TaiwanMethadone HydrochlorideSaneca Pharmaceuticals A.s.(粉)RegisteredTFDA
TaiwanMethadone Oral ConcentrateMallinckrodt Inc.口服液劑已註銷TFDA
United KingdomMethadone 1.67mg/5ml oral solution—0001NHS dm+d VMP
United KingdomMethadone 1.67mg/5ml oral suspension—0001NHS dm+d VMP
United KingdomMethadone 100mg capsules—0001NHS dm+d VMP
United KingdomMethadone 100mg impregnated cigarettes—0001NHS dm+d VMP
United KingdomMethadone 100mg suppositories—0001NHS dm+d VMP
United KingdomMethadone 100mg/5ml oral solution—0001NHS dm+d VMP
United KingdomMethadone 100mg/5ml oral suspension—0001NHS dm+d VMP
United KingdomMethadone 10mg capsules—0001NHS dm+d VMP
United StatesDisketsHikma Pharmaceuticals USA Inc.TabletlistedFDA NDC
United StatesMethadone HclLetco Medical, LLCPowderFDA NDC
United StatesMethadone HClPharma Source Direct, Inc.PowderFDA NDC
United StatesMethadone HydrochlorideHikma Pharmaceuticals USA Inc.SolutionlistedFDA NDC
United StatesMethadone HydrochloridePrecision Dose, Inc.SolutionlistedFDA NDC
United StatesMethadone HydrochloridePrecision Dose, Inc.SolutionlistedFDA NDC
United StatesMethadone HydrochlorideSpecGx LLCPowderFDA NDC
United StatesMethadone HydrochlorideSpecGx LLCConcentratelistedFDA NDC

See every manufacturer of Methadone Hydrochloride worldwide →

Regulator price references for Methadone Hydrochloride

Published list or reimbursement prices for Methadone Hydrochloride presentations, in local currency, as at the date each registry last published. These are public reference prices, not Nexara Health quotes; strength and pack differ by row.

CountryProductStrengthPackPriceTypeSourceAs of
AustraliaMethadone-AftTablet containing methadone hydrochloride 5 mg3.06 AUDex-manufacturerPBS2026-09-08
AustraliaMethadone-AftTablet containing methadone hydrochloride 5 mg3.06 AUDex-manufacturerPBS2026-09-08
AustraliaMethadone-AftTablet containing methadone hydrochloride 10 mg4.93 AUDex-manufacturerPBS2026-09-08
AustraliaPhyseptoneTablet containing methadone hydrochloride 10 mg4.93 AUDex-manufacturerPBS2026-09-08
AustraliaBiodone ForteOral liquid containing methadone hydrochloride 25 mg per 5 mL in 200 mL bottle, 1 mL7.91 AUDex-manufacturerPBS2026-09-08
AustraliaAspen Methadone SyrupOral liquid containing methadone hydrochloride 25 mg per 5 mL in 200 mL bottle, 1 mL7.91 AUDex-manufacturerPBS2026-09-08
AustraliaAspen Methadone SyrupOral liquid containing methadone hydrochloride 25 mg per 5 mL in 200 mL bottle, 1 mL7.91 AUDex-manufacturerPBS2026-09-08
AustraliaPhyseptoneInjection containing methadone hydrochloride 10 mg in 1 mL33.18 AUDex-manufacturerPBS2026-09-08
AustraliaPhyseptoneInjection containing methadone hydrochloride 10 mg in 1 mL33.18 AUDex-manufacturerPBS2026-09-08
AustraliaBiodone ForteOral liquid containing methadone hydrochloride 25 mg per 5 mL in 1 L bottle, 1 mL33.20 AUDex-manufacturerPBS2026-09-08
AustriaMethasan 5 mg Tabl.5mg7St1.45 EURKVP (Kassenverkaufspreis)eEKO (Erstattungskodex)2026-09-03
AustriaMethasan 10 mg Tabl.10mg7St2.30 EURKVP (Kassenverkaufspreis)eEKO (Erstattungskodex)2026-09-03
AustriaMethasan 20 mg Tabl.20mg7St4.20 EURKVP (Kassenverkaufspreis)eEKO (Erstattungskodex)2026-09-03
AustriaMethasan 5 mg Tabl.5mg28St4.20 EURKVP (Kassenverkaufspreis)eEKO (Erstattungskodex)2026-09-03
AustriaMethasan 10 mg Tabl.10mg28St6.85 EURKVP (Kassenverkaufspreis)eEKO (Erstattungskodex)2026-09-03
AustriaMethasan 40 mg Tabl.40mg7St7.90 EURKVP (Kassenverkaufspreis)eEKO (Erstattungskodex)2026-09-03
AustriaMethasan 60 mg Tabl.60mg7St11.30 EURKVP (Kassenverkaufspreis)eEKO (Erstattungskodex)2026-09-03
AustriaMethasan 10 mg/ml Konz. zur Herst. einer Lsg. zum Einnehmen100ml100ml12.60 EURKVP (Kassenverkaufspreis)eEKO (Erstattungskodex)2026-09-03
AustriaMethasan 20 mg Tabl.20mg28St14.25 EURKVP (Kassenverkaufspreis)eEKO (Erstattungskodex)2026-09-03
AustriaMethasan 10 mg/ml Konz. zur Herst. einer Lsg. zum Einnehmen150ml150ml18.30 EURKVP (Kassenverkaufspreis)eEKO (Erstattungskodex)2026-09-03
AustriaMethasan 40 mg Tabl.40mg28St27.60 EURKVP (Kassenverkaufspreis)eEKO (Erstattungskodex)2026-09-03
AustriaMethasan 10 mg/ml Konz. zur Herst. einer Lsg. zum Einnehmen300ml300ml34.70 EURKVP (Kassenverkaufspreis)eEKO (Erstattungskodex)2026-09-03
AustriaMethasan 60 mg Tabl.60mg28St40.15 EURKVP (Kassenverkaufspreis)eEKO (Erstattungskodex)2026-09-03
Czech RepublicMetadon Alkaloid10mg/1ml10MG/ML POR GTT SOL 1X10ML285.84 CZKmax producer price (ex-factory)SUKL SCAU2026-09-03
HungaryMetadon EP 5 mg Tabletta5mg10x hdpe tartályban + gyermekbiztos hdpe kupak570.00 HUFproducer price (ex-factory)NEAK PUPHA2026-09-03
HungaryMetadon EP 5 mg Tabletta5mg50x hdpe tartályban + gyermekbiztos hdpe kupak2,850.00 HUFproducer price (ex-factory)NEAK PUPHA2026-09-03
HungaryMetadon EP 10 mg Tabletta10mg50x hdpe tartályban + gyermekbiztos hdpe kupak5,700.00 HUFproducer price (ex-factory)NEAK PUPHA2026-09-03
HungaryMetadon EP 10 mg Tabletta10mg90x hdpe tartályban + gyermekbiztos hdpe kupak10,260.00 HUFproducer price (ex-factory)NEAK PUPHA2026-09-03
HungaryMisyo 10 mg/mL Koncentrátum Belsőleges Oldathoz1000ml1x1000ml üvegben20,640.00 HUFproducer price (ex-factory)NEAK PUPHA2026-09-03
IcelandSynthadon vet.10mg/1mlpakki3,258.00 ISKmax wholesaleLyfjastofnun lyfjaverdskra2026-09-02
IcelandInsistor10mg/1mlpakki5,150.00 ISKmax wholesaleLyfjastofnun lyfjaverdskra2026-09-02
Saudi ArabiaMETHADONE MARTINDALE PHARMA 2 mg/ml oral solution2mg/1ml174.00 SARpublicSFDA2026-09-01
Saudi ArabiaMETHADONE MARTINDALE PHARMA 2 mg/ml oral solution2mg/1ml765.50 SARpublicSFDA2026-09-01
South AfricaEquity Methadone2mg/1ml6074.69 ZARsingle exit priceDoH SEP database2026-09-01
South AfricaMethadone Adco 10mg10mg/1ml100172.67 ZARsingle exit priceDoH SEP database2026-09-01
South AfricaPhyseptone2mg/5ml100175.25 ZARsingle exit priceDoH SEP database2026-09-01
South AfricaMisyo 10 mg/ml10mg/1ml100373.60 ZARsingle exit priceDoH SEP database2026-09-01
South AfricaRutrex10mg/1ml100 ml373.68 ZARsingle exit priceDoH SEP database2026-09-01
South AfricaEquity Methadone2mg/1ml500622.54 ZARsingle exit priceDoH SEP database2026-09-01
South AfricaMethadone Adco 10mg10mg/1ml10001,726.72 ZARsingle exit priceDoH SEP database2026-09-01
South AfricaMisyo 10 mg/ml10mg/1ml10003,735.99 ZARsingle exit priceDoH SEP database2026-09-01
South AfricaRutrex10mg/1ml10003,736.89 ZARsingle exit priceDoH SEP database2026-09-01

Sourcing through Nexara Health

Nexara Health is a Health Canada–licensed wholesaler (DEL #3-002896) in Winnipeg. Because this DIN is marketed in Canada, supply normally comes through the Canadian channel; where the Canadian presentation is short or discontinued, the registrations above show which regulated markets hold an equivalent that can be imported under the Special Access Programme or for clinical comparator use. Request a quote or read how named-patient and foreign-pack supply works in Canada.

Frequently asked questions

Is Comfortan (DIN 02496658) marketed in Canada?

Yes. Health Canada lists DIN 02496658 as Marketed as of 05 Nov 2020.

Who holds the Canadian licence for this product?

Eurovet Animal Health B.v. is the company of record in the Health Canada Drug Product Database.

Is Methadone Hydrochloride registered outside Canada?

Yes — Nexara Health has matched 226 registrations in 16 other markets (see the table above).

Where does this data come from?

Health Canada Drug Product Database (DPD), DIN 02496658, status date 2020-11-05; national medicine registries: BDA, DH Drug Office, DoH SEP database, eEKO (Erstattungskodex), EU national register, FDA NDC, HPRA, Lyfjastofnun lyfjaverdskra, Medicines Authority, NEAK PUPHA, NHS dm+d VMP, NPRA, PBS, SFDA, SUKL DLP, TFDA; price sources: DoH SEP database, eEKO (Erstattungskodex), Lyfjastofnun lyfjaverdskra, NEAK PUPHA, PBS, SFDA, SUKL SCAU. Nexara Health re-checks these sources weekly and shows the last verification date at the top of the page.

Source: Health Canada Drug Product Database (DPD), DIN 02496658, status date 2020-11-05; national medicine registries: BDA, DH Drug Office, DoH SEP database, eEKO (Erstattungskodex), EU national register, FDA NDC, HPRA, Lyfjastofnun lyfjaverdskra, Medicines Authority, NEAK PUPHA, NHS dm+d VMP, NPRA, PBS, SFDA, SUKL DLP, TFDA; price sources: DoH SEP database, eEKO (Erstattungskodex), Lyfjastofnun lyfjaverdskra, NEAK PUPHA, PBS, SFDA, SUKL SCAU.

Health Canada Drug Product Database (DPD), DIN 02496658, status date 2020-11-05; national medicine registries: BDA, DH Drug Office, DoH SEP database, eEKO (Erstattungskodex), EU national register, FDA NDC, HPRA, Lyfjastofnun lyfjaverdskra, Medicines Authority, NEAK PUPHA, NHS dm+d VMP, NPRA, PBS, SFDA, SUKL DLP, TFDA; price sources: DoH SEP database, eEKO (Erstattungskodex), Lyfjastofnun lyfjaverdskra, NEAK PUPHA, PBS, SFDA, SUKL SCAU. Last reviewed 2026-09-16. Nexara Health is a licensed wholesaler and supplies licensed entities only; consumer orders are routed to a partner pharmacy.