Comfortan 10 mg Solution is a Health Canada–registered veterinary drug (DIN 02496658) held by Eurovet Animal Health B.v., containing Methadone Hydrochloride. Health Canada lists its status as Marketed (status date 05 Nov 2020). Nexara Health has matched 226 registrations of Methadone Hydrochloride across 16 other regulated markets.
Health Canada registration
| DIN | 02496658 |
|---|---|
| Brand name | Comfortan |
| Active ingredient | Methadone Hydrochloride |
| Strength | 10 mg |
| Dosage form | Solution |
| Route | Intramuscular |
| Company | Eurovet Animal Health B.v. |
| Status | Marketed — 05 Nov 2020 |
| Class | Veterinary |
| ATC | |
| AHFS | |
| Regulator record | Health Canada DPD entry · Product monograph |
Methadone Hydrochloride registered in other markets
226 registrations of the same molecule in 16 national registries outside Canada (first 81 shown, exact strength and form first). Each row is taken from the regulator's own published list; status is shown as the registry reports it.
| Country | Product | Marketing authorisation holder | Strength | Form | Status | Registry |
|---|---|---|---|---|---|---|
| Australia | Aspen Methadone Syrup | As | Oral liquid containing methadone hydrochloride 25 mg per 5 mL in 200 mL bottle, 1 mL | CA | PBS | |
| Australia | Aspen Methadone Syrup | As | Oral liquid containing methadone hydrochloride 25 mg per 5 mL in 1 L bottle, 1 mL | CA | PBS | |
| Australia | Aspen Methadone Syrup | As | Oral liquid containing methadone hydrochloride 25 mg per 5 mL in 200 mL bottle, 1 mL | PL | PBS | |
| Australia | Aspen Methadone Syrup | As | Oral liquid containing methadone hydrochloride 25 mg per 5 mL in 200 mL bottle, 1 mL | PL | PBS | |
| Australia | Methadone-Aft | Ae | Tablet containing methadone hydrochloride 5 mg | PL | PBS | |
| Australia | Methadone-Aft | Ae | Tablet containing methadone hydrochloride 5 mg | GE | PBS | |
| Australia | Physeptone | As | Injection containing methadone hydrochloride 10 mg in 1 mL | GE | PBS | |
| Australia | Physeptone | As | Tablet containing methadone hydrochloride 10 mg | GE | PBS | |
| Austria | Methasan 10 mg Tabl. | — | 28St | yellow box | eEKO (Erstattungskodex) | |
| Austria | Methasan 10 mg Tabl. | — | 7St | yellow box | eEKO (Erstattungskodex) | |
| Austria | Methasan 10 mg/ml Konz. zur Herst. einer Lsg. zum Einnehmen | — | 150ml | yellow box | eEKO (Erstattungskodex) | |
| Austria | Methasan 10 mg/ml Konz. zur Herst. einer Lsg. zum Einnehmen | — | 100ml | yellow box | eEKO (Erstattungskodex) | |
| Austria | Methasan 10 mg/ml Konz. zur Herst. einer Lsg. zum Einnehmen | — | 300ml | yellow box | eEKO (Erstattungskodex) | |
| Austria | Methasan 20 mg Tabl. | — | 7St | yellow box | eEKO (Erstattungskodex) | |
| Austria | Methasan 20 mg Tabl. | — | 28St | yellow box | eEKO (Erstattungskodex) | |
| Austria | Methasan 40 mg Tabl. | — | 7St | yellow box | eEKO (Erstattungskodex) | |
| Bulgaria | Metadon Alkaloid | Алкалоид ЕООД | 10 mg/ml oral solution | перорален разтвор | По лекарско предписание | BDA |
| Bulgaria | Methadone Sopharma | Софарма АД | 10 mg/ml oral solution | перорален разтвор | По лекарско предписание | BDA |
| Bulgaria | Methasan | G.L. Pharma GmbH | 10 mg/ml concentrate for oral solution | перорален разтвор | По лекарско предписание | BDA |
| Czech Republic | Metadon Alkaloid | — | 10MG/ML | Por Gtt Sol | F | SUKL DLP |
| Czech Republic | Misyo | — | 10MG/ML | Por Cnc Sol | R | SUKL DLP |
| Czech Republic | Sublana | — | 10MG/ML | Por Cnc Sol | R | SUKL DLP |
| Hong Kong | Methadone Linctus 80mg/20ml (New Formula) | Drug Procurement & Clinic Service Division Of The Drug Office, Department Of Health | Registered | DH Drug Office | ||
| Hong Kong | Methadone Tab BP 5 mg | Teva Pharmaceutical Hong Kong O/B Teva Pharmaceutical Hong Kong Limited | Registered | DH Drug Office | ||
| Hungary | Metadon EP 10 mg Tabletta | ExtractumPharma Gyógyszergyártó, Forgalmazó és Szaktanácsadó Zártkörűen működő részvénytársaság | 50x hdpe tartályban + gyermekbiztos hdpe kupak | NEAK PUPHA | ||
| Hungary | Metadon EP 10 mg Tabletta | ExtractumPharma Gyógyszergyártó, Forgalmazó és Szaktanácsadó Zártkörűen működő részvénytársaság | 90x hdpe tartályban + gyermekbiztos hdpe kupak | NEAK PUPHA | ||
| Hungary | Metadon EP 5 mg Tabletta | ExtractumPharma Gyógyszergyártó, Forgalmazó és Szaktanácsadó Zártkörűen működő részvénytársaság | 50x hdpe tartályban + gyermekbiztos hdpe kupak | NEAK PUPHA | ||
| Hungary | Metadon EP 5 mg Tabletta | ExtractumPharma Gyógyszergyártó, Forgalmazó és Szaktanácsadó Zártkörűen működő részvénytársaság | 10x hdpe tartályban + gyermekbiztos hdpe kupak | NEAK PUPHA | ||
| Hungary | Misyo 10 mg/mL Koncentrátum Belsőleges Oldathoz | INN-FARM d.o.o. | 1x1000ml üvegben | NEAK PUPHA | ||
| Iceland | Insistor | Icepharma - óskráð | 10 mg/ml | stl | 0 | Lyfjastofnun lyfjaverdskra |
| Iceland | Synthadon vet. | Le Vet Beheer B.V. | 10 mg/ml | stl | 0 | Lyfjastofnun lyfjaverdskra |
| Ireland | Methadone hydrochloride 1 mg/ml oral solution | Alkaloid - INT d.o.o | Oral solution | Not marketed | HPRA | |
| Ireland | Methadone Hydrochloride 5 mg tablets | Ascot Laboratories (Ireland) Limited | Tablet | Not marketed | HPRA | |
| Ireland | Methadone Hydrochloride Sugar Free 1 mg/1 ml Oral Solution | Taw Pharma (Ireland) Limited | Oral solution | Marketed | HPRA | |
| Ireland | Methadone Mixture DTF (Sugar Free) 1 mg in 1 ml Oral Solution | Ethypharm | Oral solution | Marketed | HPRA | |
| Ireland | Phymet DTF 1 mg/ml Syrup | GlaxoSmithKline (Ireland) Limited | Syrup | Not marketed | HPRA | |
| Ireland | Pinadone 1 mg/ml Oral Solution | Pinewood Laboratories Limited | Oral solution | Marketed | HPRA | |
| Malaysia | Alphadone Syrup 10mg/ml | Royce Pharma Manufacturing Sdn. Bhd. | Prescription | PRODUCT APPROVED | NPRA | |
| Malaysia | Alphadone Syrup 5mg/ml | Royce Pharma Manufacturing Sdn. Bhd. | Prescription | PRODUCT APPROVED | NPRA | |
| Malaysia | Methadyne Injection 10mg/ml | Pets Corner Sdn Bhd | Veterinary | PRODUCT APPROVED | NPRA | |
| Malta | Metasedin 5mg tablets | Central Procurement & Supplies Unit | Tablet | Authorised | Medicines Authority | |
| Netherlands | Eptadone Drank Suikervrij 10 mg/ml | L. Molteni & C. dei F.LLi Alitti Soceità di Esercizio S.p.A. | Drank | Uitsluitend recept | EU national register | |
| Netherlands | Eptadone Drank Suikervrij 5 mg/ml | L. Molteni & C. dei F.LLi Alitti Soceità di Esercizio S.p.A. | Drank | Uitsluitend recept | EU national register | |
| Netherlands | Methadon HCl Aurobindo 10 mg, tabletten | Aurobindo Pharma B.V. | Tablet | Uitsluitend recept | EU national register | |
| Netherlands | Methadon HCl Aurobindo 10 mg, tabletten | Aurobindo Pharma B.V. | Tablet | Uitsluitend recept | EU national register | |
| Netherlands | Methadon HCl Aurobindo 20 mg, tabletten | Aurobindo Pharma B.V. | Tablet | Uitsluitend recept | EU national register | |
| Netherlands | Methadon HCl Aurobindo 20 mg, tabletten | Aurobindo Pharma B.V. | Tablet | Uitsluitend recept | EU national register | |
| Netherlands | Methadon HCl Aurobindo 40 mg, tabletten | Aurobindo Pharma B.V. | Tablet | Uitsluitend recept | EU national register | |
| Netherlands | Methadon HCl Aurobindo 40 mg, tabletten | Aurobindo Pharma B.V. | Tablet | Uitsluitend recept | EU national register | |
| Saudi Arabia | METHADONE MARTINDALE PHARMA 2 mg/ml oral solution | — | 2 | Inactive | SFDA | |
| Saudi Arabia | METHADONE MARTINDALE PHARMA 2 mg/ml oral solution | — | 2 | Inactive | SFDA | |
| South Africa | Equity Methadone | Equity Pharmaceuticals (Pty) Ltd | 2 mg/ml | Syr | S6 | DoH SEP database |
| South Africa | Equity Methadone | Equity Pharmaceuticals (Pty) Ltd | 2 mg/ml | Syr | S6 | DoH SEP database |
| South Africa | Methadone Adco 10mg | Adcock Ingram Critical Care (Pty) Ltd | 10 mg/ml | Sol | S6 | DoH SEP database |
| South Africa | Methadone Adco 10mg | Adcock Ingram Critical Care (Pty) Ltd | 10 mg/ml | Sol | S6 | DoH SEP database |
| South Africa | Misyo 10 mg/ml | Umsebe Healthcare | 10 mg/ml | Sol | S6 | DoH SEP database |
| South Africa | Misyo 10 mg/ml | Umsebe Healthcare | 10 mg/ml | Sol | S6 | DoH SEP database |
| South Africa | Physeptone | Pharmacare Limited, Woodmead | 2 mg/5ml | Sus | S6 | DoH SEP database |
| South Africa | Rutrex | Arya Pharma (Pty) Ltd | 10 mg/ml | Sol | S6 | DoH SEP database |
| Taiwan | ”Molteni”Methadone Hydrochloride 5 mg/ml Oral Solution | L. Molteni & C. Dei F. Lli Alitti Societa Di Esercizio S.p.a. | 口服液劑 | 已註銷 | TFDA | |
| Taiwan | “PPCD”Methadone Oral Concentrate 10mg/mL | 衛生福利部食品藥物管理署管制藥品製藥工廠 | 內服液劑 | Registered | TFDA | |
| Taiwan | Methadone HCL | Pioneer Agro Industries Sanvin Laboratories Private Limited | (粉) | Registered | TFDA | |
| Taiwan | Methadone Hydrochloride | Rusan Pharma Ltd. | (粉) | Registered | TFDA | |
| Taiwan | Methadone Hydrochloride | Saneca Pharmaceuticals A.s. | (粉) | Registered | TFDA | |
| Taiwan | Methadone Oral Concentrate | Mallinckrodt Inc. | 口服液劑 | 已註銷 | TFDA | |
| United Kingdom | Methadone 1.67mg/5ml oral solution | — | 0001 | NHS dm+d VMP | ||
| United Kingdom | Methadone 1.67mg/5ml oral suspension | — | 0001 | NHS dm+d VMP | ||
| United Kingdom | Methadone 100mg capsules | — | 0001 | NHS dm+d VMP | ||
| United Kingdom | Methadone 100mg impregnated cigarettes | — | 0001 | NHS dm+d VMP | ||
| United Kingdom | Methadone 100mg suppositories | — | 0001 | NHS dm+d VMP | ||
| United Kingdom | Methadone 100mg/5ml oral solution | — | 0001 | NHS dm+d VMP | ||
| United Kingdom | Methadone 100mg/5ml oral suspension | — | 0001 | NHS dm+d VMP | ||
| United Kingdom | Methadone 10mg capsules | — | 0001 | NHS dm+d VMP | ||
| United States | Diskets | Hikma Pharmaceuticals USA Inc. | Tablet | listed | FDA NDC | |
| United States | Methadone Hcl | Letco Medical, LLC | Powder | FDA NDC | ||
| United States | Methadone HCl | Pharma Source Direct, Inc. | Powder | FDA NDC | ||
| United States | Methadone Hydrochloride | Hikma Pharmaceuticals USA Inc. | Solution | listed | FDA NDC | |
| United States | Methadone Hydrochloride | Precision Dose, Inc. | Solution | listed | FDA NDC | |
| United States | Methadone Hydrochloride | Precision Dose, Inc. | Solution | listed | FDA NDC | |
| United States | Methadone Hydrochloride | SpecGx LLC | Powder | FDA NDC | ||
| United States | Methadone Hydrochloride | SpecGx LLC | Concentrate | listed | FDA NDC |
See every manufacturer of Methadone Hydrochloride worldwide →
Regulator price references for Methadone Hydrochloride
Published list or reimbursement prices for Methadone Hydrochloride presentations, in local currency, as at the date each registry last published. These are public reference prices, not Nexara Health quotes; strength and pack differ by row.
| Country | Product | Strength | Pack | Price | Type | Source | As of |
|---|---|---|---|---|---|---|---|
| Australia | Methadone-Aft | Tablet containing methadone hydrochloride 5 mg | 3.06 AUD | ex-manufacturer | PBS | 2026-09-08 | |
| Australia | Methadone-Aft | Tablet containing methadone hydrochloride 5 mg | 3.06 AUD | ex-manufacturer | PBS | 2026-09-08 | |
| Australia | Methadone-Aft | Tablet containing methadone hydrochloride 10 mg | 4.93 AUD | ex-manufacturer | PBS | 2026-09-08 | |
| Australia | Physeptone | Tablet containing methadone hydrochloride 10 mg | 4.93 AUD | ex-manufacturer | PBS | 2026-09-08 | |
| Australia | Biodone Forte | Oral liquid containing methadone hydrochloride 25 mg per 5 mL in 200 mL bottle, 1 mL | 7.91 AUD | ex-manufacturer | PBS | 2026-09-08 | |
| Australia | Aspen Methadone Syrup | Oral liquid containing methadone hydrochloride 25 mg per 5 mL in 200 mL bottle, 1 mL | 7.91 AUD | ex-manufacturer | PBS | 2026-09-08 | |
| Australia | Aspen Methadone Syrup | Oral liquid containing methadone hydrochloride 25 mg per 5 mL in 200 mL bottle, 1 mL | 7.91 AUD | ex-manufacturer | PBS | 2026-09-08 | |
| Australia | Physeptone | Injection containing methadone hydrochloride 10 mg in 1 mL | 33.18 AUD | ex-manufacturer | PBS | 2026-09-08 | |
| Australia | Physeptone | Injection containing methadone hydrochloride 10 mg in 1 mL | 33.18 AUD | ex-manufacturer | PBS | 2026-09-08 | |
| Australia | Biodone Forte | Oral liquid containing methadone hydrochloride 25 mg per 5 mL in 1 L bottle, 1 mL | 33.20 AUD | ex-manufacturer | PBS | 2026-09-08 | |
| Austria | Methasan 5 mg Tabl. | 5mg | 7St | 1.45 EUR | KVP (Kassenverkaufspreis) | eEKO (Erstattungskodex) | 2026-09-03 |
| Austria | Methasan 10 mg Tabl. | 10mg | 7St | 2.30 EUR | KVP (Kassenverkaufspreis) | eEKO (Erstattungskodex) | 2026-09-03 |
| Austria | Methasan 20 mg Tabl. | 20mg | 7St | 4.20 EUR | KVP (Kassenverkaufspreis) | eEKO (Erstattungskodex) | 2026-09-03 |
| Austria | Methasan 5 mg Tabl. | 5mg | 28St | 4.20 EUR | KVP (Kassenverkaufspreis) | eEKO (Erstattungskodex) | 2026-09-03 |
| Austria | Methasan 10 mg Tabl. | 10mg | 28St | 6.85 EUR | KVP (Kassenverkaufspreis) | eEKO (Erstattungskodex) | 2026-09-03 |
| Austria | Methasan 40 mg Tabl. | 40mg | 7St | 7.90 EUR | KVP (Kassenverkaufspreis) | eEKO (Erstattungskodex) | 2026-09-03 |
| Austria | Methasan 60 mg Tabl. | 60mg | 7St | 11.30 EUR | KVP (Kassenverkaufspreis) | eEKO (Erstattungskodex) | 2026-09-03 |
| Austria | Methasan 10 mg/ml Konz. zur Herst. einer Lsg. zum Einnehmen | 100ml | 100ml | 12.60 EUR | KVP (Kassenverkaufspreis) | eEKO (Erstattungskodex) | 2026-09-03 |
| Austria | Methasan 20 mg Tabl. | 20mg | 28St | 14.25 EUR | KVP (Kassenverkaufspreis) | eEKO (Erstattungskodex) | 2026-09-03 |
| Austria | Methasan 10 mg/ml Konz. zur Herst. einer Lsg. zum Einnehmen | 150ml | 150ml | 18.30 EUR | KVP (Kassenverkaufspreis) | eEKO (Erstattungskodex) | 2026-09-03 |
| Austria | Methasan 40 mg Tabl. | 40mg | 28St | 27.60 EUR | KVP (Kassenverkaufspreis) | eEKO (Erstattungskodex) | 2026-09-03 |
| Austria | Methasan 10 mg/ml Konz. zur Herst. einer Lsg. zum Einnehmen | 300ml | 300ml | 34.70 EUR | KVP (Kassenverkaufspreis) | eEKO (Erstattungskodex) | 2026-09-03 |
| Austria | Methasan 60 mg Tabl. | 60mg | 28St | 40.15 EUR | KVP (Kassenverkaufspreis) | eEKO (Erstattungskodex) | 2026-09-03 |
| Czech Republic | Metadon Alkaloid | 10mg/1ml | 10MG/ML POR GTT SOL 1X10ML | 285.84 CZK | max producer price (ex-factory) | SUKL SCAU | 2026-09-03 |
| Hungary | Metadon EP 5 mg Tabletta | 5mg | 10x hdpe tartályban + gyermekbiztos hdpe kupak | 570.00 HUF | producer price (ex-factory) | NEAK PUPHA | 2026-09-03 |
| Hungary | Metadon EP 5 mg Tabletta | 5mg | 50x hdpe tartályban + gyermekbiztos hdpe kupak | 2,850.00 HUF | producer price (ex-factory) | NEAK PUPHA | 2026-09-03 |
| Hungary | Metadon EP 10 mg Tabletta | 10mg | 50x hdpe tartályban + gyermekbiztos hdpe kupak | 5,700.00 HUF | producer price (ex-factory) | NEAK PUPHA | 2026-09-03 |
| Hungary | Metadon EP 10 mg Tabletta | 10mg | 90x hdpe tartályban + gyermekbiztos hdpe kupak | 10,260.00 HUF | producer price (ex-factory) | NEAK PUPHA | 2026-09-03 |
| Hungary | Misyo 10 mg/mL Koncentrátum Belsőleges Oldathoz | 1000ml | 1x1000ml üvegben | 20,640.00 HUF | producer price (ex-factory) | NEAK PUPHA | 2026-09-03 |
| Iceland | Synthadon vet. | 10mg/1ml | pakki | 3,258.00 ISK | max wholesale | Lyfjastofnun lyfjaverdskra | 2026-09-02 |
| Iceland | Insistor | 10mg/1ml | pakki | 5,150.00 ISK | max wholesale | Lyfjastofnun lyfjaverdskra | 2026-09-02 |
| Saudi Arabia | METHADONE MARTINDALE PHARMA 2 mg/ml oral solution | 2mg/1ml | 174.00 SAR | public | SFDA | 2026-09-01 | |
| Saudi Arabia | METHADONE MARTINDALE PHARMA 2 mg/ml oral solution | 2mg/1ml | 765.50 SAR | public | SFDA | 2026-09-01 | |
| South Africa | Equity Methadone | 2mg/1ml | 60 | 74.69 ZAR | single exit price | DoH SEP database | 2026-09-01 |
| South Africa | Methadone Adco 10mg | 10mg/1ml | 100 | 172.67 ZAR | single exit price | DoH SEP database | 2026-09-01 |
| South Africa | Physeptone | 2mg/5ml | 100 | 175.25 ZAR | single exit price | DoH SEP database | 2026-09-01 |
| South Africa | Misyo 10 mg/ml | 10mg/1ml | 100 | 373.60 ZAR | single exit price | DoH SEP database | 2026-09-01 |
| South Africa | Rutrex | 10mg/1ml | 100 ml | 373.68 ZAR | single exit price | DoH SEP database | 2026-09-01 |
| South Africa | Equity Methadone | 2mg/1ml | 500 | 622.54 ZAR | single exit price | DoH SEP database | 2026-09-01 |
| South Africa | Methadone Adco 10mg | 10mg/1ml | 1000 | 1,726.72 ZAR | single exit price | DoH SEP database | 2026-09-01 |
| South Africa | Misyo 10 mg/ml | 10mg/1ml | 1000 | 3,735.99 ZAR | single exit price | DoH SEP database | 2026-09-01 |
| South Africa | Rutrex | 10mg/1ml | 1000 | 3,736.89 ZAR | single exit price | DoH SEP database | 2026-09-01 |
Sourcing through Nexara Health
Nexara Health is a Health Canada–licensed wholesaler (DEL #3-002896) in Winnipeg. Because this DIN is marketed in Canada, supply normally comes through the Canadian channel; where the Canadian presentation is short or discontinued, the registrations above show which regulated markets hold an equivalent that can be imported under the Special Access Programme or for clinical comparator use. Request a quote or read how named-patient and foreign-pack supply works in Canada.
Frequently asked questions
Is Comfortan (DIN 02496658) marketed in Canada?
Yes. Health Canada lists DIN 02496658 as Marketed as of 05 Nov 2020.
Who holds the Canadian licence for this product?
Eurovet Animal Health B.v. is the company of record in the Health Canada Drug Product Database.
Is Methadone Hydrochloride registered outside Canada?
Yes — Nexara Health has matched 226 registrations in 16 other markets (see the table above).
Where does this data come from?
Health Canada Drug Product Database (DPD), DIN 02496658, status date 2020-11-05; national medicine registries: BDA, DH Drug Office, DoH SEP database, eEKO (Erstattungskodex), EU national register, FDA NDC, HPRA, Lyfjastofnun lyfjaverdskra, Medicines Authority, NEAK PUPHA, NHS dm+d VMP, NPRA, PBS, SFDA, SUKL DLP, TFDA; price sources: DoH SEP database, eEKO (Erstattungskodex), Lyfjastofnun lyfjaverdskra, NEAK PUPHA, PBS, SFDA, SUKL SCAU. Nexara Health re-checks these sources weekly and shows the last verification date at the top of the page.
Source: Health Canada Drug Product Database (DPD), DIN 02496658, status date 2020-11-05; national medicine registries: BDA, DH Drug Office, DoH SEP database, eEKO (Erstattungskodex), EU national register, FDA NDC, HPRA, Lyfjastofnun lyfjaverdskra, Medicines Authority, NEAK PUPHA, NHS dm+d VMP, NPRA, PBS, SFDA, SUKL DLP, TFDA; price sources: DoH SEP database, eEKO (Erstattungskodex), Lyfjastofnun lyfjaverdskra, NEAK PUPHA, PBS, SFDA, SUKL SCAU.
Health Canada Drug Product Database (DPD), DIN 02496658, status date 2020-11-05; national medicine registries: BDA, DH Drug Office, DoH SEP database, eEKO (Erstattungskodex), EU national register, FDA NDC, HPRA, Lyfjastofnun lyfjaverdskra, Medicines Authority, NEAK PUPHA, NHS dm+d VMP, NPRA, PBS, SFDA, SUKL DLP, TFDA; price sources: DoH SEP database, eEKO (Erstattungskodex), Lyfjastofnun lyfjaverdskra, NEAK PUPHA, PBS, SFDA, SUKL SCAU. Last reviewed 2026-09-16. Nexara Health is a licensed wholesaler and supplies licensed entities only; consumer orders are routed to a partner pharmacy.