METHYLENE BLUE INJECTION 10 MG — DIN 02487993
METHYLENE BLUE : 10 MG · PHEBRA PTY LTD · SOLUTION · wholesale supply in Canada
Health Canada status: MARKETED
What is METHYLENE BLUE INJECTION?
METHYLENE BLUE INJECTION 10 MG contains METHYLENE BLUE : 10 MG. It is listed in the Health Canada Drug Product Database under DIN 02487993, held by PHEBRA PTY LTD, supplied as SOLUTION for INTRAVENOUS administration. Health Canada currently lists it as marketed, status dated 22-Sep-2020. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is METHYLENE BLUE INJECTION used for?
Used in the treatment of methemoglobinemia. Also used as a bacteriological stain, as a dye in diagnostic procedures such as fistula detection, and for the delineation of certain body tissues during surgery.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
Is there a generic Methylthioninium Chloride in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
11 holders have a Canadian DIN containing Methylthioninium Chloride, across 11 DINs, of which 2 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| OMEGA LABORATORIES LIMITED | 1 | 1 | METHYLENE BLUE INJECTION USP | Sourceable in Canada |
| PHEBRA PTY LTD | 1 | 1 | METHYLENE BLUE INJECTION | Sourceable in Canada |
| ALLEN & HANBURYS A GLAXO CANADA LTD. CO. | 1 | 0 | METHYLENE BLUE INJ 1% | No marketed DIN |
| ALVEDA PHARMACEUTICALS INC | 1 | 0 | METHYLENE BLUE INJECTION USP | No marketed DIN |
| DAVID BULL LABORATORIES (PTY) LTD. | 1 | 0 | METHYLENE BLUE INJ 1% USP | No marketed DIN |
| GLAXO CANADA INC | 1 | 0 | METHYLENE BLUE INJ 10MG/ML USP | No marketed DIN |
| HIKMA CANADA LIMITED | 1 | 0 | METHYLENE BLUE INJECTION USP | No marketed DIN |
| HOSPIRA HEALTHCARE ULC | 1 | 0 | METHYLENE BLUE INJECTION, USP | No marketed DIN |
| LABORATOIRE ATLAS INC | 1 | 0 | METHYLENE BLEU LIQ 2% | No marketed DIN |
| MYLAN PHARMACEUTICALS ULC | 1 | 0 | METHYLENE BLUE INJECTION, USP | No marketed DIN |
| SANDOZ CANADA INCORPORATED | 1 | 0 | METHYLENE BLUE INJECTION USP | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 10 MG |
|---|---|
| Dosage form | SOLUTION |
| Route | INTRAVENOUS |
| Pack configuration (monograph) | Vials of 5 mL, boxes of 10. |
| Storage | Store at room temperature (15°C to 30°C). |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Methylthioninium Chloride |
|---|---|
| ATC code | V03AB17 |
| AHFS class | 28:16.08.04 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02487993 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2487993 |
| Brand name | METHYLENE BLUE INJECTION |
| Generic / active ingredient | METHYLENE BLUE : 10 MG |
| Market authorization holder | PHEBRA PTY LTD |
| Health Canada schedule | Ethical |
| ATC code | V03AB17 |
| ATC anatomical main group | V — Various |
| ATC therapeutic subgroup | V03AB |
| Current status | MARKETED |
| Status date | 22-Sep-2020 |
| Original market date | 2019-07-09 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
2 of 11 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| METHYLENE BLUE INJECTION USP | 10 MG | LIQUID | OMEGA LABORATORIES LIMITED | MARKETED | 02230770 |
| METHYLENE BLEU LIQ 2% | 2 % | LIQUID | LABORATOIRE ATLAS INC | CANCELLED POST MARKET | 00050474 |
| METHYLENE BLUE INJ 1% | 10 MG | LIQUID | ALLEN & HANBURYS A GLAXO CANADA LTD. CO. | CANCELLED POST MARKET | 00465062 |
| METHYLENE BLUE INJ 1% USP | 1 % | LIQUID | DAVID BULL LABORATORIES (PTY) LTD. | CANCELLED POST MARKET | 00863610 |
| METHYLENE BLUE INJ 10MG/ML USP | 10 MG | LIQUID | GLAXO CANADA INC | CANCELLED POST MARKET | 01958674 |
| METHYLENE BLUE INJECTION USP | 10 MG | SOLUTION | HIKMA CANADA LIMITED | CANCELLED POST MARKET | 02431548 |
| METHYLENE BLUE INJECTION USP | 10 MG | SOLUTION | SANDOZ CANADA INCORPORATED | CANCELLED POST MARKET | 00816108 |
| METHYLENE BLUE INJECTION USP | 10 MG | SOLUTION | ALVEDA PHARMACEUTICALS INC | CANCELLED (UNRETURNED ANNUAL) | 02302756 |
| METHYLENE BLUE INJECTION, USP | 10 MG | SOLUTION | MYLAN PHARMACEUTICALS ULC | CANCELLED PRE MARKET | 02094665 |
| METHYLENE BLUE INJECTION, USP | 1 % | LIQUID | HOSPIRA HEALTHCARE ULC | CANCELLED POST MARKET | 02137194 |
2 · Same class — other molecules in ATC V03AB
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Naloxone | INJECTABLE NALOXONE HYDROCHLORIDE · KLOXXADO · NALOXONE HCL INJECTION - 0.4MG/ML USP · NALOXONE HCL INJECTION - 1MG/ML USP · +11 more | 26 | 12 | Yes |
| Sugammadex | BRIDION · PMS-SUGAMMADEX · SUGAMMADEX · SUGAMMADEX INJECTION · +1 more | 14 | 4 | Yes |
| Thiosulphate | SEACALPHYX · SODIUM THIOSULFATE INJ 25% USP · SODIUM THIOSULFATE INJECTION USP | 4 | 3 | Yes |
| Methylthioninium Chloride | METHYLENE BLEU LIQ 2% · METHYLENE BLUE INJ 1% · METHYLENE BLUE INJ 1% USP · METHYLENE BLUE INJ 10MG/ML USP · +3 more | 11 | 2 | Yes |
| Flumazenil | ANEXATE INJ 0.1MG/ML · FLUMAZENIL INJECTION · FLUMAZENIL INJECTION SDZ · FLUMAZENIL INJECTION, USP · +1 more | 6 | 2 | Yes |
| Protamine | PROTAMINE SULFATE INJ 10MG/ML USP · PROTAMINE SULFATE INJECTION USP · PROTAMINE SULFATE INJECTION, USP | 4 | 2 | Yes |
| Fomepizole | ANTIZOL · FOMEPIZOLE FOR INJECTION | 2 | 2 | Yes |
| Hydroxocobalamin | CYANOKIT | 2 | 1 | Yes |
| Digitalis Antitoxin | DIGIBIND · DIGIFAB | 2 | 1 | Yes |
| Idarucizimab | PRAXBIND | 1 | 1 | Yes |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC V03A
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| V03AC | Deferasirox · Deferiprone · Deferoxamine | 57 | 44 |
| V03AN | Carbon Dioxide · Combination · Helium · Medical Air · Medical Gases · +2 more | 112 | 43 |
| V03AE | Calcium Acetate · Drugs For Treatment Of Hyperkalemia And Hyperphosphatemia · Lanthanum Carbonate · Patiromer Calcium · Polystyrene Sulphonate · +3 more | 40 | 19 |
| V03AF | Amifostine · Calcium Folinate · Dexrazoxane · Mesna · Palifermin · +1 more | 34 | 16 |
| V03AH | Diazoxide | 2 | 1 |
| V03AX | Cobicistat · Difelikefalin · Other Therapeutic Products | 8 | 1 |
| V03AZ | Ethanol | 1 | 0 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.