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ENGERIX-B 10 MCG / 0.5 ML

HEPATITIS B SURFACE ANTIGEN (RECOMBINANT) : 10 MCG / 0.5 ML · DIN 02487020 · GLAXOSMITHKLINE INC

Health Canada status: MARKETED

What is ENGERIX-B?

ENGERIX-B 10 MCG / 0.5 ML contains HEPATITIS B SURFACE ANTIGEN (RECOMBINANT) : 10 MCG / 0.5 ML. It is listed in the Health Canada Drug Product Database under DIN 02487020, held by GLAXOSMITHKLINE INC, supplied as SUSPENSION for INTRAMUSCULAR administration. Health Canada currently lists it as marketed, status dated 07-Oct-2019. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.

What is ENGERIX-B used for?

ENGERIX-B (hepatitis B surface antigen (recombinant)) is indicated for: active immunization against hepatitis B virus infection.

Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.

Product details and regulatory record

DIN02487020
Brand nameENGERIX-B
Generic / active ingredientHEPATITIS B SURFACE ANTIGEN (RECOMBINANT) : 10 MCG / 0.5 ML
ManufacturerGLAXOSMITHKLINE INC
Strength10 MCG / 0.5 ML
Dosage formSUSPENSION
Route of administrationINTRAMUSCULAR
ScheduleSchedule D
ATC codeJ07BC01 HEPATITIS B, PURIFIED ANTIGEN
AHFS class80:12.00
BiosimilarNo
Health Canada statusMARKETED
Status date07-Oct-2019
Original market date2019-10-07 00:00:00

How is it stored and handled?

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How is it supplied?

0.5 mL single dose prefilled syringes are packaged in a 1 pack carton with a Package Leaflet. 1.0 mL single dose prefilled syringes are packaged in a 1 or 25 pack carton with a Package Leaflet.

What can be used instead?

Other Canadian products sharing ATC code J07BC01 HEPATITIS B, PURIFIED ANTIGEN. 3 of 9 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.

ProductStrengthFormManufacturerHealth Canada statusDIN
ENGERIX-B20 MCG / 1 MLSUSPENSIONGLAXOSMITHKLINE INCMARKETEDDIN 02487039
RECOMBIVAX HB40 MCGSUSPENSIONMERCK CANADA INCMARKETEDDIN 02245977
ENGERIX-B10 MCG / 0.5 MLSUSPENSIONGLAXOSMITHKLINE INCCANCELLED POST MARKETDIN 02296454
ENGERIX-B20 MCG / 1 MLSUSPENSIONGLAXOSMITHKLINE INCCANCELLED POST MARKETDIN 01919431
PREHEVBRIO10 MCGSUSPENSIONVBI VACCINES INC.APPROVEDDIN 02533286
RECOMBIVAX HB10 MCGSUSPENSIONMERCK CANADA INCCANCELLED POST MARKETDIN 02243676
RECOMBIVAX HB (ADULT DIALYSIS WITH PRESERVATIVE)40 MCGSOLUTIONMERCK CANADA INCCANCELLED POST MARKETDIN 01934023
RECOMBIVAX HB (WITH PRESERVATIVE)10 MCGSOLUTIONMERCK CANADA INCCANCELLED POST MARKETDIN 00749486

Who else supplies HEPATITIS B, PURIFIED ANTIGEN worldwide?

Nexara tracks national medicine registries and published price lists across multiple markets. HEPATITIS B, PURIFIED ANTIGEN appears in 66 registered pack listings across 8 markets, published on 6 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.

Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.

How can I get it?

Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.

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Ordering questions

Who can buy this from Nexara?

Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.

Is there a minimum order?

Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.

What is the lead time?

Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.

Can Nexara supply this for a clinical trial?

Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.

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Health Canada Drug Product Database (DPD), DIN 02487020. Last reviewed 2026-09-08. Nexara Health is a licensed wholesaler and supplies licensed entities only; consumer orders are routed to a partner pharmacy.