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HYDROMORPHONE HYDROCHLORIDE INJECTION USP 40 MG / 100 ML

HYDROMORPHONE HYDROCHLORIDE : 40 MG / 100 ML · DIN 02485540 · STERINOVA INC.

Health Canada status: MARKETED

What is HYDROMORPHONE HYDROCHLORIDE INJECTION USP?

HYDROMORPHONE HYDROCHLORIDE INJECTION USP 40 MG / 100 ML contains HYDROMORPHONE HYDROCHLORIDE : 40 MG / 100 ML. It is listed in the Health Canada Drug Product Database under DIN 02485540, held by STERINOVA INC., supplied as SOLUTION for INTRAVENOUS administration. Health Canada currently lists it as marketed, status dated 28-Aug-2019. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.

What is HYDROMORPHONE HYDROCHLORIDE INJECTION USP used for?

Exclusively for the relief of severe pain in patients who require intravenously administered opioids in doses or concentrations higher than those usually needed.

Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.

Product details and regulatory record

DIN02485540
Brand nameHYDROMORPHONE HYDROCHLORIDE INJECTION USP
Generic / active ingredientHYDROMORPHONE HYDROCHLORIDE : 40 MG / 100 ML
ManufacturerSTERINOVA INC.
Strength40 MG / 100 ML
Dosage formSOLUTION
Route of administrationINTRAVENOUS
ScheduleNARCOTICS (CDSA I)
ATC codeN02AA03 HYDROMORPHONE
AHFS class28:08.08
BiosimilarNo
Health Canada statusMARKETED
Status date28-Aug-2019
Original market date2019-08-28 00:00:00

How is it administered?

For IV use in opioid-tolerant patients only. Dose based on relative potency of previous opioid. Titrate slowly. Do not stop abruptly; taper gradually. Administer by trained professionals.

Included because it drives pack selection and wastage. Consult the monograph.

How is it stored and handled?

Store securely to avoid theft or misuse. (Specific temperature range not provided in text, though USP standard usually implies controlled room temperature).

How is it supplied?

0.2 mg/mL in 100 mL flexible plastic containers; 0.4 mg/mL in 50 mL and 100 mL flexible plastic containers.

Contraindications

Hypersensitivity to hydromorphone; opioid-naive patients; GI obstruction; surgical abdomen; asthma/COPD; respiratory depression; alcoholism; head injury; MAOIs; pregnancy/breastfeeding.

Warnings and precautions

High dose formulation for opioid-tolerant patients only. Risk of addiction, abuse, misuse, and fatal respiratory depression. Avoid alcohol. Risk of profound sedation with benzodiazepines.

Is HYDROMORPHONE in shortage in Canada?

A Canadian shortage report is on file for this molecule: Active — reported by STERIMAX INC, last seen 04 Sep 2026. A shortage on one presentation does not always affect every DIN of the molecule — the alternatives below list what else is marketed in Canada. Nexara can confirm current availability and identify substitutions or import options where permitted.

Check availability for HYDROMORPHONE HYDROCHLORIDE INJECTION USP

What can be used instead?

Other Canadian products sharing ATC code N02AA03 HYDROMORPHONE. 34 of 85 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.

ProductStrengthFormManufacturerHealth Canada statusDIN
APO-HYDROMORPHONE1 MGTABLETAPOTEX INCMARKETEDDIN 02364115
APO-HYDROMORPHONE2 MGTABLETAPOTEX INCMARKETEDDIN 02364123
APO-HYDROMORPHONE4 MGTABLETAPOTEX INCMARKETEDDIN 02364131
APO-HYDROMORPHONE8 MGTABLETAPOTEX INCMARKETEDDIN 02364158
DILAUDID1 MGTABLETPURDUE PHARMAMARKETEDDIN 00705438
DILAUDID2 MGTABLETPURDUE PHARMAMARKETEDDIN 00125083
DILAUDID4 MGTABLETPURDUE PHARMAMARKETEDDIN 00125121
DILAUDID8 MGTABLETPURDUE PHARMAMARKETEDDIN 00786543
HYDROMORPH CONTIN4.5 MGCAPSULE (SUSTAINED-RELEASE)PURDUE PHARMAMARKETEDDIN 02359502
HYDROMORPH CONTIN9 MGCAPSULE (SUSTAINED-RELEASE)PURDUE PHARMAMARKETEDDIN 02359510

Who else supplies HYDROMORPHONE worldwide?

Nexara tracks national medicine registries and published price lists across multiple markets. HYDROMORPHONE appears in 134 registered pack listings across 6 markets, published on 6 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.

Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.

How can I get it?

Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.

Request a quote for HYDROMORPHONE HYDROCHLORIDE INJECTION USP

Ordering questions

Who can buy this from Nexara?

Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.

Is there a minimum order?

Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.

What is the lead time?

Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.

Can Nexara supply this for a clinical trial?

Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.

Health Canada Drug Product Database (DPD), DIN 02485540. Last reviewed 2026-09-08. Nexara Health is a licensed wholesaler and supplies licensed entities only; consumer orders are routed to a partner pharmacy.