DEMYLOCAN 50 MG
DECITABINE : 50 MG · DIN 02484811 · PENDOPHARM DIVISION OF PHARMASCIENCE INC
Health Canada status: MARKETED
What is DEMYLOCAN?
DEMYLOCAN 50 MG contains DECITABINE : 50 MG. It is listed in the Health Canada Drug Product Database under DIN 02484811, held by PENDOPHARM DIVISION OF PHARMASCIENCE INC, supplied as POWDER for INTRAVENOUS administration. Health Canada currently lists it as marketed, status dated 24-Mar-2021. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is DEMYLOCAN used for?
Treatment of adult patients with Myelodysplastic Syndromes (MDS) including all FAB subtypes and IPSS intermediate-1, intermediate-2, and high-risk groups.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
Product details and regulatory record
| DIN | 02484811 |
|---|---|
| Brand name | DEMYLOCAN |
| Generic / active ingredient | DECITABINE : 50 MG |
| Manufacturer | PENDOPHARM DIVISION OF PHARMASCIENCE INC |
| Strength | 50 MG |
| Dosage form | POWDER |
| Route of administration | INTRAVENOUS |
| Schedule | Prescription |
| ATC code | L01BC08 DECITABINE |
| AHFS class | 84:80.00 |
| Biosimilar | No |
| Health Canada status | MARKETED |
| Status date | 24-Mar-2021 |
How is it administered?
Option 1: 15 mg/m2 IV over 3 hours every 8 hours for 3 days, every 6 weeks. Option 2: 20 mg/m2 IV over 1 hour daily for 5 days, every 4 weeks. Minimum 4 cycles recommended.
Included because it drives pack selection and wastage. Consult the monograph.
How is it stored and handled?
Unopened vials: Store at 15-30°C. Reconstituted solution: Use within 15 mins or store diluted solution at 2-8°C for up to 4 hours.
How is it supplied?
Single-dose 20 mL colourless glass vial, packaged in cartons of 1 vial. Each vial contains 50 mg of decitabine.
Contraindications
Hypersensitivity to decitabine or any ingredient in the formulation; breastfeeding women.
Warnings and precautions
Should be administered under supervision of experienced professional. Serious risks: Neutropenia, thrombocytopenia, fetal harm, and potential for infertility. May cause fatigue and dizziness.
What can be used instead?
Other Canadian products sharing ATC code L01BC08 DECITABINE. 1 of 2 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.
| Product | Strength | Form | Manufacturer | Health Canada status | DIN |
|---|---|---|---|---|---|
| DACOGEN | 50 MG | POWDER | OTSUKA PHARMACEUTICAL CO LTD | APPROVED | DIN 02490366 |
Who else supplies DECITABINE worldwide?
Nexara tracks national medicine registries and published price lists across multiple markets. DECITABINE appears in 6 registered pack listings across 3 markets, published on 3 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.
Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.