METHOTREXATE INJECTION BP 25 MG
METHOTREXATE (METHOTREXATE SODIUM) : 25 MG · DIN 02474891 · ACCORD HEALTHCARE INC
Health Canada status: MARKETED
What is METHOTREXATE INJECTION BP?
METHOTREXATE INJECTION BP 25 MG contains METHOTREXATE (METHOTREXATE SODIUM) : 25 MG. It is listed in the Health Canada Drug Product Database under DIN 02474891, held by ACCORD HEALTHCARE INC, supplied as SOLUTION for INTRAVENOUS administration. Health Canada currently lists it as marketed, status dated 23-Apr-2019. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is METHOTREXATE INJECTION BP used for?
Methotrexate Injection BP is indicated for Neoplastic diseases such as Choriocarcinoma, Non-Hodgkin's Lymphoma, Breast Cancer, Acute Lymphoblastic Leukemia, Head and Neck Cancer, Gastric Cancer, Metastasis of unknown primary, Osteogenic sarcoma (adjuvant), Bladder Cancer (advanced), Leptomeningeal spread of malignancies, Burkitt's lymphoma, advanced stages of childhood lymphoma, and advanced cases of mycosis fungoides (cutaneous T-cell lymphoma). It is also indicated as a Disease Modifying Antirheumatic Drug (DMARD) for severe disabling psoriasis/psoriatic arthritis, severe disabling rheumatoid arthritis (RA), and severe disabling seronegative arthritides.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
Product details and regulatory record
| DIN | 02474891 |
|---|---|
| Brand name | METHOTREXATE INJECTION BP |
| Generic / active ingredient | METHOTREXATE (METHOTREXATE SODIUM) : 25 MG |
| Manufacturer | ACCORD HEALTHCARE INC |
| Strength | 25 MG |
| Dosage form | SOLUTION |
| Route of administration | INTRAVENOUS |
| Schedule | Prescription |
| ATC code | L01BA01 METHOTREXATE |
| AHFS class | 28:08.12 |
| Biosimilar | No |
| Health Canada status | MARKETED |
| Status date | 23-Apr-2019 |
| Original market date | 2018-11-22 00:00:00 |
How is it stored and handled?
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How is it supplied?
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Is METHOTREXATE in shortage in Canada?
A Canadian shortage report is on file for this molecule: Resolved — reported by ACCORD HEALTHCARE INC, last seen 04 Sep 2026. A shortage on one presentation does not always affect every DIN of the molecule — the alternatives below list what else is marketed in Canada. Nexara can confirm current availability and identify substitutions or import options where permitted.
What can be used instead?
Other Canadian products sharing ATC code L01BA01 METHOTREXATE. 20 of 51 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.
| Product | Strength | Form | Manufacturer | Health Canada status | DIN |
|---|---|---|---|---|---|
| ACH-METHOTREXATE | 2.5 MG | TABLET | ACCORD HEALTHCARE INC | MARKETED | DIN 02509067 |
| APO-METHOTREXATE | 2.5 MG | TABLET | APOTEX INC | MARKETED | DIN 02182963 |
| JAMP METHOTREXATE TABLETS | 10 MG | TABLET | JAMP PHARMA CORPORATION | MARKETED | DIN 02553740 |
| M-METHOTREXATE | 2.5 MG | TABLET | MANTRA PHARMA INC | MARKETED | DIN 02534916 |
| METHOTREXATE INJECTION BP | 25 MG | SOLUTION | ACCORD HEALTHCARE INC | MARKETED | DIN 02474735 |
| METHOTREXATE INJECTION BP | 25 MG | SOLUTION | ACCORD HEALTHCARE INC | MARKETED | DIN 02327236 |
| METHOTREXATE INJECTION BP | 25 MG | SOLUTION | ACCORD HEALTHCARE INC | MARKETED | DIN 02464365 |
| METHOTREXATE INJECTION USP | 10 MG | SOLUTION | PFIZER CANADA ULC | MARKETED | DIN 02182947 |
| METHOTREXATE INJECTION USP | 25 MG | SOLUTION | PFIZER CANADA ULC | MARKETED | DIN 02182777 |
| METHOTREXATE INJECTION USP | 25 MG | SOLUTION | PFIZER CANADA ULC | MARKETED | DIN 02182955 |
Who else supplies METHOTREXATE worldwide?
Nexara tracks national medicine registries and published price lists across multiple markets. METHOTREXATE appears in 251 registered pack listings across 12 markets, published on 10 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.
Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.