NIGHTTIME SLEEP AID 50 MG / 30 ML — DIN 02464683
DIPHENHYDRAMINE HYDROCHLORIDE : 50 MG / 30 ML · JUNO OTC INC · SOLUTION · wholesale supply in Canada
Health Canada status: MARKETED
What is NIGHTTIME SLEEP AID?
NIGHTTIME SLEEP AID 50 MG / 30 ML contains DIPHENHYDRAMINE HYDROCHLORIDE : 50 MG / 30 ML. It is listed in the Health Canada Drug Product Database under DIN 02464683, held by JUNO OTC INC, supplied as SOLUTION for ORAL administration. Health Canada currently lists it as marketed, status dated 14-Jun-2018. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
How much does Diphenhydramine cost around the world?
Diphenhydramine is listed on 5 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Morocco publishes a PPV (public price); Saudi Arabia publishes a public; South Africa publishes a single exit price. Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| United States | acquisition | 5 | 24 | USD███.██ |
| South Africa | single exit price | 2 | 3 | ZAR███.██ |
| United Arab Emirates | public | 2 | 2 | AED███.██ |
| Morocco | PPV (public price) | 1 | 1 | MAD███.██ |
| Saudi Arabia | public | 1 | 1 | SAR███.██ |
31 pack listings across 11 brand entries and 4 price bases, refreshed 05 Sep 2026. Ranges span every Diphenhydramine pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Diphenhydramine in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
63 holders have a Canadian DIN containing Diphenhydramine, across 183 DINs, of which 51 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| VITA HEALTH PRODUCTS INC | 13 | 9 | ALLERGY FORMULA, ALLERGY FORMULA EXTRA STRENGTH, ALLERGY FORMULA LIQUID CAPSULES, CHILDREN'S COUGH, COLD & ALLERGY STRIPS, EXTRA STRENGTH ALLERGY FORMULA LIQUID CAPSULES, +8 more | Sourceable in Canada |
| MEDTECH PRODUCTS INC | 11 | 9 | EXTRA STRENGTH NYTOL QUICKGELS, EXTRA STRENGTH NYTOL TAB 50MG, NYTOL EXTRA STRENGTH SLEEP AID CAPLET 50MG, NYTOL TABLET 25MG, SLEEP-EZE D EXTRA STRENGTH CAPSULES, +6 more | Sourceable in Canada |
| MCNEIL CONSUMER HEALTHCARE DIVISION OF JOHNSON & JOHNSON INC | 21 | 8 | BENADRYL ALLERGY, BENADRYL ALLERGY LIQUID, BENADRYL ALLERGY LIQUIGELS, BENADRYL ALLERGY QUICK DISSOLVE STRIPS, BENADRYL CAPSULES 50MG, +14 more | Sourceable in Canada |
| JUNO OTC INC | 7 | 5 | ALLERGY FORMULA, ALLERGY FORMULA CAPLETS, CHILDREN'S ALLERGY FORMULA RAPID MELTS, CHILDREN'S CLEAR ALLERGY FORMULA, NIGHTTIME SLEEP AID, +2 more | Sourceable in Canada |
| PROCTER & GAMBLE INC | 5 | 4 | ZZZQUIL, ZZZQUIL ALCOHOL FREE, ZZZQUIL LIQUID, ZZZQUIL NIGHTTIME SLEEP AID, ZZZQUIL SLEEP AID | Sourceable in Canada |
| JAMP PHARMA CORPORATION | 5 | 3 | CHILDREN'S LIQUID ALLERGY FORMULA, DIPHENHYDRAMINE HYDROCHLORIDE ELIXIR USP, JAMP DIPHENHYDRAMINE 25 MG, JAMP DIPHENHYDRAMINE 50 MG, JAMP DIPHENHYDRAMINE CHILDREN'S SYRUP | Sourceable in Canada |
| TEVA CANADA LIMITED | 12 | 2 | ALLER-AIDE, ALLER-AIDE ELIXIR, ALLER-AIDE PLUS, ALLERGY FORMULA, ALLERGY FORMULA ELIXIR, +7 more | Sourceable in Canada |
| LABORATOIRE LALCO INC. | 3 | 2 | DORMIPHEN COMPRIME, DORMIPHEN EXTRA-FORT CAPSULE, DORMIPHEN EXTRA-FORT COMPRIME | Sourceable in Canada |
| PENDOPHARM DIVISION OF PHARMASCIENCE INC | 2 | 2 | PDP-DIPHENHYDRAMINE, PDP-DIPHENHYDRAMINE EXTRA STRENGTH/ EXTRA FORT | Sourceable in Canada |
| PERRIGO INTERNATIONAL | 6 | 1 | ALLERGY FORMULA CAPLETS, ALLERGY FORMULA LIQUID, CLEAR ALLERGY FORMULA FOR CHILDREN AND ADULTS, NIGHTTIME SLEEP AID LIQUID, SLEEP AID LIQUID GELS, +1 more | Sourceable in Canada |
| ENDO OPERATIONS LTD. | 2 | 1 | UNISOM, UNISOM SLEEPGELS EXTRA STRENGTH | Sourceable in Canada |
| FRESENIUS KABI CANADA LTD | 1 | 1 | DIPHENHYDRAMINE HYDROCHLORIDE INJECTION, USP | Sourceable in Canada |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 50 MG / 30 ML |
|---|---|
| Dosage form | SOLUTION |
| Route | ORAL |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation, because this listing covers more than one of them.
Substance and classification
| Active substance | Diphenhydramine |
|---|---|
| ATC code | R06AA02 |
| AHFS class | 04:04.04 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02464683 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2464683 |
| Brand name | NIGHTTIME SLEEP AID |
| Generic / active ingredient | DIPHENHYDRAMINE HYDROCHLORIDE : 50 MG / 30 ML |
| Market authorization holder | JUNO OTC INC |
| Health Canada schedule | NON-PRESCRIPTION DRUGS |
| ATC code | R06AA02 |
| ATC anatomical main group | R — Respiratory system |
| ATC therapeutic subgroup | R06AA |
| Current status | MARKETED |
| Status date | 14-Jun-2018 |
| Original market date | 2018-06-14 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
Is Diphenhydramine in shortage in Canada?
A Canadian shortage report is on file for a product containing this molecule: Resolved — reported by SANDOZ CANADA INCORPORATED, last seen 17 Aug 2026. A shortage on one presentation does not always affect every DIN of the molecule — the alternatives below list what else is marketed in Canada. Nexara can confirm current availability and identify substitutions or import options where permitted.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
51 of 183 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| ALLERGY FORMULA | 12.5 MG / 5 ML | SOLUTION | JUNO OTC INC | MARKETED | 02465108 |
| ALLERGY FORMULA | 25 MG | TABLET | VITA HEALTH PRODUCTS INC | MARKETED | 02229492 |
| ALLERGY FORMULA CAPLETS | 25 MG | TABLET | PERRIGO INTERNATIONAL | MARKETED | 02141728 |
| ALLERGY FORMULA CAPLETS | 25 MG | TABLET | SIGMA LIFE SCIENCES INC. | MARKETED | 02479710 |
| ALLERGY FORMULA EXTRA STRENGTH | 50 MG | TABLET | VITA HEALTH PRODUCTS INC | MARKETED | 02490943 |
| ALLERGY FORMULA LIQUID CAPSULES | 25 MG | CAPSULE | VITA HEALTH PRODUCTS INC | MARKETED | 02306352 |
| ALLERNIX | 25 MG | TABLET | TEVA CANADA LIMITED | MARKETED | 02097583 |
| ALLERNIX EXTRA STRENGTH | 50 MG | TABLET | TEVA CANADA LIMITED | MARKETED | 02097575 |
| BENADRYL ALLERGY | 25 MG | TABLET | MCNEIL CONSUMER HEALTHCARE DIVISION OF JOHNSON & JOHNSON INC | MARKETED | 02017849 |
| BENADRYL ALLERGY LIQUID | 12.5 MG / 5 ML | SOLUTION | MCNEIL CONSUMER HEALTHCARE DIVISION OF JOHNSON & JOHNSON INC | MARKETED | 02019736 |
2 · Same class — other molecules in ATC R06AA
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Diphenhydramine | AG-DIPHENHYDRAMINE 25 MG · AG-DIPHENHYDRAMINE 50 MG · ALLER-AIDE · ALLER-AIDE ELIXIR · +155 more | 183 | 51 | Yes |
| Dimenhydrinate | AG-DIMENHYDRINATE · ANTI-NAUSEANT · ANTI-NAUSEANT LIQUID GELS · ANTI-NAUSEANT TABLET · +56 more | 70 | 20 | Yes |
| Doxylamine, Combinations | ALOG-DOXYLAMINE/PYRIDOXINE · APO-DOXYLAMINE/B6 · DICLECTIN · PMS-DOXYLAMINE-PYRIDOXINE · +1 more | 5 | 4 | Yes |
| Diphenhydramine, Combinations | BENADRYL ALLERGY & SINUS · BUCKLEY'S NIGHTTIME COUGH & CONGESTION | 2 | 1 | Yes |
| Clemastine | TAVIST TABLETS 1MG | 1 | 0 | Not in Canada |
| Diphenylpyraline, Combinations | JAMP-COUGH SUPPOSITORIES ADULT | 1 | 0 | Not in Canada |
| Doxylamine | UNISOM-2 TABLETS | 1 | 0 | Not in Canada |
| Dimenhydrinate, Combinations | GRAVERGOL CAPSULES | 1 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC R06A
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| R06AX | Astemizole · Azatadine · Bilastine · Cyproheptadine · Desloratadine · +6 more | 84 | 38 |
| R06AE | Cetirizine · Cyclizine · Meclozine · Meclozine, Combinations | 69 | 27 |
| R06AB | Brompheniramine · Chlorpheniramine · Dexchlorpheniramine | 17 | 1 |
| R06AD | Alimemazine · Promethazine | 17 | 1 |
| R06AC | Tripelennamine | 1 | 0 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is NIGHTTIME SLEEP AID called?
The same molecule, Diphenhydramine, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| Sleepeze-PM | Latin | South Africa |
| Advil® Night | Latin | United Arab Emirates |
| BENADRYL | Latin | Morocco |
| Diphen-cool | Latin | United Arab Emirates |
| OTRICOLD FILM COATED TABLETS | Latin | Saudi Arabia |
| Procof | Latin | South Africa |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.