CYANOCOBALAMIN INJECTION USP 1000 MCG — DIN 02463393
VITAMIN B12 : 1000 MCG · HIKMA CANADA LIMITED · SOLUTION · wholesale supply in Canada
Health Canada status: MARKETED
What is CYANOCOBALAMIN INJECTION USP?
CYANOCOBALAMIN INJECTION USP 1000 MCG contains VITAMIN B12 : 1000 MCG. It is listed in the Health Canada Drug Product Database under DIN 02463393, held by HIKMA CANADA LIMITED, supplied as SOLUTION for SUBCUTANEOUS ; INTRAMUSCULAR administration. Health Canada currently lists it as marketed, status dated 20-Apr-2022. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is CYANOCOBALAMIN INJECTION USP used for?
For vitamin B12 deficiency occurring in pernicious anemia with or without neurological complications. Other macrocytic, megaloblastic anemias where etiology suggests malabsorption of vitamin B12 such as following: gastrectomy, gastric carcinoma, megaloblastic anemia associated with such gastrointestinal disorders as sprue syndrome, blind loops and anastomoses and fish tapeworm. The injection is also suitable for use as the flushing dose in the Schilling (vitamin B12 absorption) test for pernicious anemia.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How much does Cyanocobalamin cost around the world?
Cyanocobalamin is listed on 8 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Bahrain publishes a retail (max); Iceland publishes a max wholesale; Romania publishes a max producer price. Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| United States | acquisition | 4 | 37 | USD███.██ |
| Bahrain | retail (max) | 5 | 9 | BHD███.██ |
| United Arab Emirates | public | 4 | 8 | AED███.██ |
| Iceland | max wholesale | 5 | 5 | ISK███.██ |
| Saudi Arabia | public | 5 | 5 | SAR███.██ |
| South Africa | single exit price | 4 | 4 | ZAR███.██ |
| Romania | max producer price | 2 | 2 | RON███.██ |
| United Kingdom | hospital | 1 | 1 | GBP███.██ |
71 pack listings across 30 brand entries and 7 price bases, refreshed 03 Sep 2026. Ranges span every Cyanocobalamin pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Cyanocobalamin in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
49 holders have a Canadian DIN containing Cyanocobalamin, across 67 DINs, of which 4 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| HIKMA CANADA LIMITED | 2 | 2 | CYANOCOBALAMIN INJECTION USP | Sourceable in Canada |
| SANDOZ CANADA INCORPORATED | 2 | 1 | VITAMIN B12 | Sourceable in Canada |
| STERIMAX INC | 1 | 1 | CYANOCOBALAMIN INJECTION USP | Sourceable in Canada |
| PHARMAVITE LLC | 3 | 0 | VITAMIN B12 TAB 100MCG, VITAMIN B12 TAB 250MCG, VITAMIN B12 TAB 500MCG | No marketed DIN |
| VITA HEALTH PRODUCTS INC | 3 | 0 | VITAMIN B12 250MCG TABLETS, VITAMIN B12 TAB 25MCG | No marketed DIN |
| WN PHARMACEUTICALS LTD. | 3 | 0 | B12 250MCG CYANOCOBALAMIN, VITAMIN B12 100 MCG, VITAMIN B12 1000 MCG | No marketed DIN |
| FLORA MANUFACTURING AND DISTRIBUTING LTD. | 2 | 0 | VITAMIN B12 1000 MCG, VITAMIN B12 500 MCG | No marketed DIN |
| GAHLER ENTERPRISES LTD. | 2 | 0 | B-12 1000MCG CONTINUOUS RELEASED TAB, VITAMIN B12 TAB 250MCG | No marketed DIN |
| GREAT EARTH COMPANIES, INC. | 2 | 0 | VITAMIN B12 100MCG, VITAMIN B12 500MCG | No marketed DIN |
| HOSPIRA HEALTHCARE ULC | 2 | 0 | VITAMIN B12 INJ 1000MCG/ML, VITAMIN B12 INJ 100MCG/ML | No marketed DIN |
| LABORATOIRE LALCO INC. | 2 | 0 | VITAMINE B12 250MCG, VITAMINE B12 TAB 25MCG | No marketed DIN |
| NUTRISTAR HEALTH PRODUCTS (1987) INC. | 2 | 0 | VITAMIN B12 TAB 100MCG, VITAMIN B12 TAB 250MCG | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 1000 MCG |
|---|---|
| Dosage form | SOLUTION |
| Route | SUBCUTANEOUS ; INTRAMUSCULAR |
| Pack configuration (monograph) | amber glass single use ampoules of 1 mL, boxes of 10, and amber glass multidose vials of 10 mL, boxes of 1 |
| Storage | Store between 15 and 30°C. Protect from light. Use vial within 28 days of first puncture when stored between 15 and 30°C. |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Cyanocobalamin |
|---|---|
| ATC code | B03BA01 |
| AHFS class | 88:08.00 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02463393 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2463393 |
| Brand name | CYANOCOBALAMIN INJECTION USP |
| Generic / active ingredient | VITAMIN B12 : 1000 MCG |
| Market authorization holder | HIKMA CANADA LIMITED |
| Health Canada schedule | Ethical |
| ATC code | B03BA01 |
| ATC anatomical main group | B — Blood and blood-forming organs |
| ATC therapeutic subgroup | B03BA |
| Current status | MARKETED |
| Status date | 20-Apr-2022 |
| Original market date | 2018-01-16 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
Is Cyanocobalamin in shortage in Canada?
A Canadian shortage report is on file for a product containing this molecule: Resolved — reported by HIKMA CANADA LIMITED, last seen 17 Aug 2026. A shortage on one presentation does not always affect every DIN of the molecule — the alternatives below list what else is marketed in Canada. Nexara can confirm current availability and identify substitutions or import options where permitted.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
4 of 67 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| CYANOCOBALAMIN INJECTION USP | 1000 MCG | SOLUTION | HIKMA CANADA LIMITED | MARKETED | 02465507 |
| CYANOCOBALAMIN INJECTION USP | 1000 MCG | SOLUTION | STERIMAX INC | MARKETED | 01987003 |
| VITAMIN B12 | 1000 MCG | SOLUTION | SANDOZ CANADA INCORPORATED | MARKETED | 00521515 |
| AJ-CYANOCOBALAMIN | 1000 MCG | SOLUTION | AGILA JAMP CANADA INC | CANCELLED PRE MARKET | 02417405 |
| B-12 1000 INJ 1000MCG/ML | 1 MG | SOLUTION | OMEGA LABORATORIES LIMITED | CANCELLED POST MARKET | 00626112 |
| B-12 1000MCG CONTINUOUS RELEASED TAB | 1 MG | TABLET (EXTENDED-RELEASE) | GAHLER ENTERPRISES LTD. | CANCELLED POST MARKET | 00535036 |
| B-PLEX | 50 MCG | TABLET | BEVERLY INTERNATIONAL NUTRITION | CANCELLED POST MARKET | 00652210 |
| B12 1000MCG | 1000 MCG | TABLET | NATURAL FACTORS NUTRITIONAL PRODUCTS LTD. | CANCELLED POST MARKET | 02242579 |
| B12 250MCG CYANOCOBALAMIN | 250 MCG | TABLET | WN PHARMACEUTICALS LTD. | CANCELLED POST MARKET | 02243652 |
| BEDOZ 1000INJ | 1 MG | LIQUID | LAB NADEAU LTÉE, DIVISION OF TECHNILAB INC. | CANCELLED POST MARKET | 00286583 |
2 · Same class — other molecules in ATC B03BA
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Cyanocobalamin | AJ-CYANOCOBALAMIN · B-12 1000 INJ 1000MCG/ML · B-12 1000MCG CONTINUOUS RELEASED TAB · B-PLEX · +47 more | 67 | 4 | Yes |
| Cyanocobalamin, Combinations | B6, B12 & FOLIC ACID · BIO-B12 · COOL B · FORMULA CH. LES. · +7 more | 11 | 0 | Not in Canada |
| Hydroxocobalamin | HYDRO COBEX INJ 1000MCG/ML · HYDROXOCOBALAMIN INJ 1000MCG/ML · HYDROXY COBAL INJ 1000MCG/ML | 3 | 0 | Not in Canada |
| Cobamamide, Combinations | ACTI-FOLIC + DIBENCOZIDE CAPLETS | 1 | 0 | Not in Canada |
| Cobamamide | CO B12 | 1 | 0 | Not in Canada |
| Hydroxocobalamin, Combinations | ACTI-HYDROXO/DIBENCOZ 500 + FOLIC ACID TAB | 1 | 0 | Not in Canada |
| Mecobalamin | B12 1000MCG (METHYLCOBALAMIN) | 1 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC B03B
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| B03BB | Folic Acid · Folic Acid, Combinations | 43 | 3 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is CYANOCOBALAMIN INJECTION USP called?
The same molecule, Cyanocobalamin, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| NEUROBION | Latin | Bahrain |
| Neurobion® coated tablets | Latin | United Arab Emirates |
| BETOLVEX | Latin | Bahrain |
| Neurobion® Ampoules | Latin | United Arab Emirates |
| B COMPLETE AMPOULE | Latin | Saudi Arabia |
| Catosal | Latin | Iceland |
| CYNOVIT | Latin | Bahrain |
| CYTOBION | Latin | Saudi Arabia |
| EPINOSINE B FORTE | Latin | Bahrain |
| Ialuvit Ophthalmic Solution | Latin | United Arab Emirates |
| Medivitan® iV | Latin | United Arab Emirates |
| Nascobal | Latin | Iceland |
| NEURORUBINE | Latin | Bahrain |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.