AFINITOR DISPERZ 3 MG
EVEROLIMUS : 3 MG · DIN 02425653 · NOVARTIS PHARMACEUTICALS CANADA INC
Health Canada status: MARKETED
What is AFINITOR DISPERZ?
AFINITOR DISPERZ 3 MG contains EVEROLIMUS : 3 MG. It is listed in the Health Canada Drug Product Database under DIN 02425653, held by NOVARTIS PHARMACEUTICALS CANADA INC, supplied as TABLET FOR SUSPENSION for ORAL administration. Health Canada currently lists it as marketed, status dated 28-Nov-2014. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is AFINITOR DISPERZ used for?
HR-positive, HER2-negative advanced breast cancer; Pancreatic NET; GI/Lung NET; Metastatic RCC; Renal angiomyolipoma (TSC); SEGA (TSC); Adjunctive treatment of seizures (TSC).
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
Product details and regulatory record
| DIN | 02425653 |
|---|---|
| Brand name | AFINITOR DISPERZ |
| Generic / active ingredient | EVEROLIMUS : 3 MG |
| Manufacturer | NOVARTIS PHARMACEUTICALS CANADA INC |
| Strength | 3 MG |
| Dosage form | TABLET FOR SUSPENSION |
| Route of administration | ORAL |
| Schedule | Prescription |
| ATC code | L04AH02 EVEROLIMUS |
| AHFS class | 10:00.00 |
| Biosimilar | No |
| Health Canada status | MARKETED |
| Status date | 28-Nov-2014 |
| Original market date | 2014-11-28 00:00:00 |
How is it administered?
Once daily at the same time, consistently with or without food. Oncology/Renal Angiomyolipoma: 10 mg daily. SEGA/Seizures: Starting dose based on BSA (4.5-9 mg/m2) with titration to 5-15 ng/mL.
Included because it drives pack selection and wastage. Consult the monograph.
How is it stored and handled?
Not explicitly detailed in provided text (section 11 mentioned in TOC but text cuts off).
How is it supplied?
Not explicitly detailed in provided text (mentions tablets and tablets for oral suspension in various strengths).
Contraindications
Hypersensitivity to everolimus, other rapamycin derivatives, or any ingredient in the formulation. Contraindicated for seizures in populations without a definite diagnosis of TSC.
Warnings and precautions
Non-infectious pneumonitis, infections, and renal failure (all potentially fatal). Risk of delayed developmental landmarks in pediatrics. Dosage forms are not interchangeable.
What can be used instead?
Other Canadian products sharing ATC code L04AH02 EVEROLIMUS. 21 of 28 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.
| Product | Strength | Form | Manufacturer | Health Canada status | DIN |
|---|---|---|---|---|---|
| AFINITOR | 10 MG | TABLET | NOVARTIS PHARMACEUTICALS CANADA INC | MARKETED | DIN 02339528 |
| AFINITOR | 2.5 MG | TABLET | NOVARTIS PHARMACEUTICALS CANADA INC | MARKETED | DIN 02369257 |
| AFINITOR | 5 MG | TABLET | NOVARTIS PHARMACEUTICALS CANADA INC | MARKETED | DIN 02339501 |
| AFINITOR DISPERZ | 2 MG | TABLET FOR SUSPENSION | NOVARTIS PHARMACEUTICALS CANADA INC | MARKETED | DIN 02425645 |
| AFINITOR DISPERZ | 5 MG | TABLET FOR SUSPENSION | NOVARTIS PHARMACEUTICALS CANADA INC | MARKETED | DIN 02425661 |
| NAT-EVEROLIMUS | 10 MG | TABLET | NATCO PHARMA (CANADA) INC | MARKETED | DIN 02530120 |
| NAT-EVEROLIMUS | 2.5 MG | TABLET | NATCO PHARMA (CANADA) INC | MARKETED | DIN 02530090 |
| NAT-EVEROLIMUS | 5 MG | TABLET | NATCO PHARMA (CANADA) INC | MARKETED | DIN 02530104 |
| PMS-EVEROLIMUS | 10 MG | TABLET | PHARMASCIENCE INC | MARKETED | DIN 02504693 |
| PMS-EVEROLIMUS | 2.5 MG | TABLET | PHARMASCIENCE INC | MARKETED | DIN 02504677 |
Who else supplies EVEROLIMUS worldwide?
Nexara tracks national medicine registries and published price lists across multiple markets. EVEROLIMUS appears in 433 registered pack listings across 14 markets, published on 12 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.
Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.