HUMULIN R (KWIKPEN) 100 UNIT — DIN 02415089
INSULIN BIOSYNTHETIC HUMAN BR : 100 UNIT · ELI LILLY CANADA INC · SOLUTION · wholesale supply in Canada
Health Canada status: MARKETED
What is HUMULIN R (KWIKPEN)?
HUMULIN R (KWIKPEN) 100 UNIT contains INSULIN BIOSYNTHETIC HUMAN BR : 100 UNIT. It is listed in the Health Canada Drug Product Database under DIN 02415089, held by ELI LILLY CANADA INC, supplied as SOLUTION for INTRAMUSCULAR ; SUBCUTANEOUS administration. Health Canada currently lists it as marketed, status dated 03-Mar-2014. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is HUMULIN R (KWIKPEN) used for?
Treatment of insulin requiring diabetic patients. HUMULIN-R is also used for diabetic emergencies (coma/pre-coma) and during surgery.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How much does Insulin (Human) cost around the world?
Insulin (Human) is listed on 3 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Greece publishes a producer price (ex-factory); Norway publishes a max AUP (pharmacy retail); South Africa publishes a single exit price. Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| Greece | producer price (ex-factory) | 41 | 41 | EUR███.██ |
| Norway | max AUP (pharmacy retail) | 5 | 6 | NOK███.██ |
| South Africa | single exit price | 1 | 2 | ZAR███.██ |
49 pack listings across 47 brand entries and 3 price bases, refreshed 07 Sep 2026. Ranges span every Insulin (Human) pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Insulin (Human) in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
5 holders have a Canadian DIN containing Insulin (Human), across 9 DINs, of which 4 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| ELI LILLY CANADA INC | 3 | 2 | HUMULIN R, HUMULIN R (KWIKPEN), HUMULIN R CARTRIDGE | Sourceable in Canada |
| NOVO NORDISK CANADA INC | 2 | 1 | NOVOLIN GE TORONTO, NOVOLIN GE TORONTO PENFILL | Sourceable in Canada |
| BAXTER CORPORATION | 1 | 1 | MYXREDLIN | Sourceable in Canada |
| NOVO NORDISK A/S | 2 | 0 | NOVOLINSET GE TORONTO INJ LIQ 100U/ML, VELOSULIN HUMAN INJ LIQ 100U/ML | No marketed DIN |
| ELI LILLY AND COMPANY LIMITED | 1 | 0 | ILETIN INSULIN REGULAR 100UNIT/ML | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 100 UNIT |
|---|---|
| Dosage form | SOLUTION |
| Route | INTRAMUSCULAR ; SUBCUTANEOUS |
| Pack configuration (monograph) | 10 mL vials, 3 mL vials, 3.0 mL cartridges (5/box), and 3.0 mL prefilled KwikPens (5/box). |
| Storage | Unused: Store at 2-8°C (refrigerator). Do not freeze. In-use: Store at room temperature and discard after 28 days. Keep away from direct sunlight. |
| Shipping class | Cold chain — validated shipper with temperature monitoring |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Cold chain. This product is stored refrigerated. Nexara ships it on a validated cold chain with temperature monitoring; a delivery address that cannot receive and store it at 2–8 °C on arrival must be flagged before the order is placed.
Substance and classification
| Active substance | Insulin (Human) |
|---|---|
| ATC code | A10AB01 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02415089 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2415089 |
| Brand name | HUMULIN R (KWIKPEN) |
| Generic / active ingredient | INSULIN BIOSYNTHETIC HUMAN BR : 100 UNIT |
| Market authorization holder | ELI LILLY CANADA INC |
| Health Canada schedule | Schedule D |
| ATC code | A10AB01 |
| ATC anatomical main group | A — Alimentary tract and metabolism |
| ATC therapeutic subgroup | A10AB |
| Current status | MARKETED |
| Status date | 03-Mar-2014 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
How is it administered?
Dosage determined by physician. HUMULIN-R: SC, IM, or IV. HUMULIN-N and 30/70: SC only. Rotate injection sites. Usually injected before breakfast.
Included because it drives pack selection and wastage. Consult the monograph.
Contraindications
During episodes of hypoglycemia; hypersensitivity to human insulin or any excipients. HUMULIN-N and 30/70 must not be given intravenously or used for diabetic coma.
Warnings and precautions
Hypoglycemia is the most common adverse effect. Uncorrected reactions can cause coma or death. Do not share pens/cartridges. Use caution when transferring between insulin types.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
4 of 9 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| HUMULIN R CARTRIDGE | 100 UNIT | SOLUTION | ELI LILLY CANADA INC | MARKETED | 01959220 |
| MYXREDLIN | 1 UNIT | SOLUTION | BAXTER CORPORATION | MARKETED | 02529602 |
| NOVOLIN GE TORONTO | 100 UNIT | SOLUTION | NOVO NORDISK CANADA INC | MARKETED | 02024233 |
| HUMULIN R | 100 UNIT | SOLUTION | ELI LILLY CANADA INC | CANCELLED POST MARKET | 00586714 |
| ILETIN INSULIN REGULAR 100UNIT/ML | 100 UNIT | LIQUID | ELI LILLY AND COMPANY LIMITED | CANCELLED POST MARKET | 00446564 |
| NOVOLIN GE TORONTO PENFILL | 100 UNIT | SOLUTION | NOVO NORDISK CANADA INC | CANCELLED POST MARKET | 02024284 |
| NOVOLINSET GE TORONTO INJ LIQ 100U/ML | 100 UNIT | LIQUID | NOVO NORDISK A/S | CANCELLED POST MARKET | 02025256 |
| VELOSULIN HUMAN INJ LIQ 100U/ML | 100 UNIT | LIQUID | NOVO NORDISK A/S | CANCELLED POST MARKET | 01986805 |
2 · Same class — other molecules in ATC A10AB
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Insulin Lispro | ADMELOG · ADMELOG SOLOSTAR · HUMALOG · HUMALOG (CARTRIDGE) · +4 more | 13 | 8 | Yes |
| Insulin Aspart | FIASP · KIRSTY · NOVORAPID · TRURAPI | 11 | 8 | Yes |
| Insulin (Human) | HUMULIN R · HUMULIN R (KWIKPEN) · HUMULIN R CARTRIDGE · ILETIN INSULIN REGULAR 100UNIT/ML · +5 more | 9 | 4 | Yes |
| Insulin Glulisine | APIDRA | 4 | 3 | Yes |
| Insulin (Pork) | HYPURIN REGULAR INSULIN PORK · REGULAR PURIFIED PORK INSULIN INJ | 2 | 1 | Yes |
| Insulin (Beef) | SULPHATED INSULIN INJ LIQ 100U/ML | 1 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC A10A
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| A10AE | Insulin (Human) · Insulin Degludec · Insulin Degludec And Liraglutide · Insulin Detemir · Insulin Glargine · +2 more | 23 | 15 |
| A10AD | Insulin (Human) · Insulin Aspart · Insulin Lispro | 31 | 9 |
| A10AC | Insulin (Human) · Insulin (Pork) | 13 | 5 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is HUMULIN R (KWIKPEN) called?
The same molecule, Insulin (Human), is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| Actrapid HM (ge) | Latin | South Africa |
| Insuman Rapid | Latin | Norway |
| Humulin NPH | Latin | Norway |
| Humulin NPH KwikPen | Latin | Norway |
| Insuman Infusat | Latin | Norway |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.