APO-QUINAPRIL/HCTZ 20 MG — DIN 02408783
QUINAPRIL (QUINAPRIL HYDROCHLORIDE) : 20 MG HYDROCHLOROTHIAZIDE : 25 MG · APOTEX INC · TABLET · wholesale supply in Canada
Health Canada status: MARKETED
What is APO-QUINAPRIL/HCTZ?
APO-QUINAPRIL/HCTZ 20 MG contains QUINAPRIL (QUINAPRIL HYDROCHLORIDE) : 20 MG HYDROCHLOROTHIAZIDE : 25 MG. It is listed in the Health Canada Drug Product Database under DIN 02408783, held by APOTEX INC, supplied as TABLET for ORAL administration. Health Canada currently lists it as marketed, status dated 16-Jun-2025. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is APO-QUINAPRIL/HCTZ used for?
APO - QUINAPRIL/HCTZ (quinapril hydrochloride and hydrochlorothiazide) is indicated for the treatment of essential hypertension in patients for whom combination therapy is appropriate. APO - QUINAPRIL/HCTZ is not indicated for initial therapy. Patients should be titrated on the individual drugs. If the fixed combination represents the dosage determined by this titration, the use of APO - QUINAPRIL/HCTZ may be more convenient in the management of patients.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How much does Quinapril And Diuretics cost around the world?
Quinapril And Diuretics is listed on 6 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Australia publishes a ex-manufacturer; Italy publishes a prezzo al pubblico (classe A); Morocco publishes a PPV (public price). Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| South Africa | single exit price | 14 | 14 | ZAR███.██ |
| Australia | ex-manufacturer | 2 | 3 | AUD███.██ |
| Italy | prezzo al pubblico (classe A) | 3 | 3 | EUR███.██ |
| Morocco | PPV (public price) | 1 | 2 | MAD███.██ |
| Saudi Arabia | public | 2 | 2 | SAR███.██ |
| Spain | PVP con IVA (public price) | 1 | 1 | EUR███.██ |
25 pack listings across 23 brand entries and 6 price bases, refreshed 08 Sep 2026. Ranges span every Quinapril And Diuretics pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Quinapril And Diuretics in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
6 holders have a Canadian DIN containing Quinapril And Diuretics, across 20 DINs, of which 8 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| APOTEX INC | 6 | 3 | APO-QUINAPRIL / HCTZ TABLETS, APO-QUINAPRIL/HCTZ | Sourceable in Canada |
| AURO PHARMA INC | 3 | 3 | AURO-QUINAPRIL HCTZ | Sourceable in Canada |
| JAMP PHARMA CORPORATION | 2 | 2 | JAMP QUINAPRIL / HCTZ | Sourceable in Canada |
| GENMED A DIVISION OF PFIZER CANADA ULC | 3 | 0 | GD-QUINAPRIL HCTZ | No marketed DIN |
| PFIZER CANADA ULC | 3 | 0 | ACCURETIC | No marketed DIN |
| TEVA CANADA LIMITED | 3 | 0 | TEVA-QUINAPRIL/HCTZ | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 20 MG |
|---|---|
| Dosage form | TABLET |
| Route | ORAL |
| Pack configuration (monograph) | Blister Pack of 28 (2 X 14) tablets and HDPE bottles of 90 tablets. |
| Storage | null |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Quinapril And Diuretics |
|---|---|
| ATC code | C09BA06 |
| AHFS class | 24:32.04 ; 40:28.20 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02408783 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2408783 |
| Brand name | APO-QUINAPRIL/HCTZ |
| Generic / active ingredient | QUINAPRIL (QUINAPRIL HYDROCHLORIDE) : 20 MG HYDROCHLOROTHIAZIDE : 25 MG |
| Market authorization holder | APOTEX INC |
| Health Canada schedule | Prescription |
| ATC code | C09BA06 |
| ATC anatomical main group | C — Cardiovascular system |
| ATC therapeutic subgroup | C09BA |
| Current status | MARKETED |
| Status date | 16-Jun-2025 |
| Original market date | 2013-08-13 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
8 of 20 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| APO-QUINAPRIL/HCTZ | 10 MG | TABLET | APOTEX INC | MARKETED | 02408767 |
| APO-QUINAPRIL/HCTZ | 12.5 MG | TABLET | APOTEX INC | MARKETED | 02408775 |
| AURO-QUINAPRIL HCTZ | 25 MG | TABLET | AURO PHARMA INC | MARKETED | 02473321 |
| AURO-QUINAPRIL HCTZ | 12.5 MG | TABLET | AURO PHARMA INC | MARKETED | 02473305 |
| AURO-QUINAPRIL HCTZ | 12.5 MG | TABLET | AURO PHARMA INC | MARKETED | 02473291 |
| JAMP QUINAPRIL / HCTZ | 20 MG | TABLET | JAMP PHARMA CORPORATION | MARKETED | 02547449 |
| JAMP QUINAPRIL / HCTZ | 12.5 MG | TABLET | JAMP PHARMA CORPORATION | MARKETED | 02547430 |
| ACCURETIC | 20 MG | TABLET | PFIZER CANADA ULC | CANCELLED POST MARKET | 02237368 |
| ACCURETIC | 10 MG | TABLET | PFIZER CANADA ULC | CANCELLED POST MARKET | 02237367 |
| ACCURETIC | 25 MG | TABLET | PFIZER CANADA ULC | CANCELLED POST MARKET | 02237369 |
2 · Same class — other molecules in ATC C09BA
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Perindopril And Diuretics | AG-PERINDOPRIL / INDAPAMIDE · APO-PERINDOPRIL-INDAPAMIDE · ARCOSYL PLUS · ARCOSYL PLUS LD · +16 more | 36 | 25 | Yes |
| Lisinopril And Diuretics | APO-LISINOPRIL/HCTZ · AVA-LISINOPRIL HCT · LISINOPRIL/HCTZ (TYPE Z) · LISNOPRIL/HCTZ (TYPE P) · +9 more | 39 | 12 | Yes |
| Quinapril And Diuretics | ACCURETIC · APO-QUINAPRIL / HCTZ TABLETS · APO-QUINAPRIL/HCTZ · AURO-QUINAPRIL HCTZ · +3 more | 20 | 8 | Yes |
| Ramipril And Diuretics | ALTACE HCT · APO-RAMIPRIL/HCTZ · PMS-RAMIPRIL-HCTZ · RAMIPRIL-HCTZ · +2 more | 32 | 7 | Yes |
| Enalapril And Diuretics | ENALAPRIL MALEATE/HCTZ · ENALAPRIL/HCTZ · TEVA-ENALAPRIL/HCTZ · VASERETIC | 7 | 3 | Yes |
| Cilazapril And Diuretics | APO-CILAZAPRIL/HCTZ · INHIBACE PLUS · TEVA-CILAZAPRIL/HCTZ | 3 | 2 | Yes |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC C09B
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| C09BB | Perindopril And Amlodipine · Ramipril And Felodipine · Trandolapril And Verapamil | 15 | 9 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is APO-QUINAPRIL/HCTZ called?
The same molecule, Quinapril And Diuretics, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| ACCUPRIL | Latin | Morocco |
| APO-Quinapril | Latin | Australia |
| ACQUIN | Latin | Australia |
| Quinaspen | Latin | South Africa |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.