ORENCIA 125 MG
ABATACEPT : 125 MG · DIN 02402475 · BRISTOL-MYERS SQUIBB CANADA
Health Canada status: MARKETED
What is ORENCIA?
ORENCIA 125 MG contains ABATACEPT : 125 MG. It is listed in the Health Canada Drug Product Database under DIN 02402475, held by BRISTOL-MYERS SQUIBB CANADA, supplied as SOLUTION for SUBCUTANEOUS administration. Health Canada currently lists it as marketed, status dated 09-May-2013. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is ORENCIA used for?
Adult RA (reducing signs/symptoms, inhibiting structural damage); Polyarticular JIA/JRA (6+ years); Adult Psoriatic Arthritis (PsA); Prophylaxis of acute Graft versus Host Disease (aGVHD).
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
Product details and regulatory record
| DIN | 02402475 |
|---|---|
| Brand name | ORENCIA |
| Generic / active ingredient | ABATACEPT : 125 MG |
| Manufacturer | BRISTOL-MYERS SQUIBB CANADA |
| Strength | 125 MG |
| Dosage form | SOLUTION |
| Route of administration | SUBCUTANEOUS |
| Schedule | Prescription |
| ATC code | L04AA24 ABATACEPT |
| AHFS class | 90:24.92 |
| Biosimilar | No |
| Health Canada status | MARKETED |
| Status date | 09-May-2013 |
| Original market date | 2013-05-09 00:00:00 |
How is it administered?
IV: 30-min infusion (weight-based: <60kg: 500mg, 60-100kg: 750mg, >100kg: 1g) at weeks 0, 2, 4, then every 4 weeks. SC: 125mg once weekly. aGVHD: 10mg/kg IV on Days -1, 5, 14, 28.
Included because it drives pack selection and wastage. Consult the monograph.
How is it stored and handled?
Fully diluted IV solution: store at room temperature or refrigerated (2-8°C) for up to 24 hours. (Note: Specific unopened vial storage not in snippet).
How is it supplied?
IV: 250 mg/15 mL single-use vial with silicone-free syringe. SC: 125 mg/mL single-dose prefilled syringes with needle guard (cartons of 1 or 4).
Contraindications
Known hypersensitivity to ORENCIA or its components; patients with or at risk of sepsis syndrome, such as immunocompromised and HIV+ patients.
Warnings and precautions
Serious infections (sepsis, pneumonia, TB); fatal anaphylaxis reported; potential for malignancies; maltose in IV form may cause false high blood glucose readings.
What can be used instead?
Other Canadian products sharing ATC code L04AA24 ABATACEPT. 2 of 3 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.
| Product | Strength | Form | Manufacturer | Health Canada status | DIN |
|---|---|---|---|---|---|
| ORENCIA | 250 MG | POWDER FOR SOLUTION | BRISTOL-MYERS SQUIBB CANADA | MARKETED | DIN 02282097 |
| ORENCIA | 125 MG | SOLUTION | BRISTOL-MYERS SQUIBB CANADA | CANCELLED PRE MARKET | DIN 02461919 |
Who else supplies ABATACEPT worldwide?
Nexara tracks national medicine registries and published price lists across multiple markets. ABATACEPT appears in 31 registered pack listings across 11 markets, published on 9 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.
Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.