SILENOR 6 MG
DOXEPIN (DOXEPIN HYDROCHLORIDE) : 6 MG · DIN 02398265 · KNIGHT THERAPEUTICS INC.
Health Canada status: MARKETED
What is SILENOR?
SILENOR 6 MG contains DOXEPIN (DOXEPIN HYDROCHLORIDE) : 6 MG. It is listed in the Health Canada Drug Product Database under DIN 02398265, held by KNIGHT THERAPEUTICS INC., supplied as TABLET for ORAL administration. Health Canada currently lists it as marketed, status dated 22-Jan-2026. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is SILENOR used for?
Treatment and symptomatic relief of insomnia characterized by frequent nocturnal awakening, and/or early morning awakenings.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
Product details and regulatory record
| DIN | 02398265 |
|---|---|
| Brand name | SILENOR |
| Generic / active ingredient | DOXEPIN (DOXEPIN HYDROCHLORIDE) : 6 MG |
| Manufacturer | KNIGHT THERAPEUTICS INC. |
| Strength | 6 MG |
| Dosage form | TABLET |
| Route of administration | ORAL |
| Schedule | Prescription |
| ATC code | N06AA12 DOXEPIN |
| Biosimilar | No |
| Health Canada status | MARKETED |
| Status date | 22-Jan-2026 |
How is it administered?
Adults: 6 mg once daily (3 mg if indicated). Geriatrics: 3 mg once daily (up to 6 mg). Take within 30 minutes of bedtime, at least 3 hours after a meal.
Included because it drives pack selection and wastage. Consult the monograph.
How is it stored and handled?
Not explicitly detailed in provided text (section 11 listed in TOC but content not in snippet).
How is it supplied?
Bottles of 30 tablets.
Contraindications
Hypersensitivity to doxepin or dibenzoxepine compounds; untreated narrow angle glaucoma; severe urinary retention; use of MAOIs within the past two weeks.
Warnings and precautions
CNS depressant effects; complex sleep-related behaviours (e.g., sleep-driving); potential for worsening of depression/suicidal ideation; caution when driving or operating machinery.
What can be used instead?
Other Canadian products sharing ATC code N06AA12 DOXEPIN. 22 of 51 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.
| Product | Strength | Form | Manufacturer | Health Canada status | DIN |
|---|---|---|---|---|---|
| APO-DOXEPIN | 10 MG | CAPSULE | APOTEX INC | MARKETED | DIN 02049996 |
| APO-DOXEPIN | 100 MG | CAPSULE | APOTEX INC | MARKETED | DIN 02050048 |
| APO-DOXEPIN | 25 MG | CAPSULE | APOTEX INC | MARKETED | DIN 02050005 |
| APO-DOXEPIN | 50 MG | CAPSULE | AA PHARMA INC | MARKETED | DIN 02050013 |
| APO-DOXEPIN | 75 MG | CAPSULE | APOTEX INC | MARKETED | DIN 02050021 |
| JAMP DOXEPIN | 10 MG | CAPSULE | JAMP PHARMA CORPORATION | MARKETED | DIN 02559250 |
| JAMP DOXEPIN | 100 MG | CAPSULE | JAMP PHARMA CORPORATION | MARKETED | DIN 02559293 |
| JAMP DOXEPIN | 25 MG | CAPSULE | JAMP PHARMA CORPORATION | MARKETED | DIN 02559269 |
| JAMP DOXEPIN | 50 MG | CAPSULE | JAMP PHARMA CORPORATION | MARKETED | DIN 02559277 |
| JAMP DOXEPIN | 75 MG | CAPSULE | JAMP PHARMA CORPORATION | MARKETED | DIN 02559285 |
Who else supplies DOXEPIN worldwide?
Nexara tracks national medicine registries and published price lists across multiple markets. DOXEPIN appears in 11 registered pack listings across 3 markets, published on 3 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.
Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.