GRANISETRON HYDROCHLORIDE INJECTION SDZ 1 MG — DIN 02385414
GRANISETRON (GRANISETRON HYDROCHLORIDE) : 1 MG · SANDOZ CANADA INCORPORATED · SOLUTION · wholesale supply in Canada
Health Canada status: CANCELLED POST MARKET
What is GRANISETRON HYDROCHLORIDE INJECTION SDZ?
GRANISETRON HYDROCHLORIDE INJECTION SDZ 1 MG contains GRANISETRON (GRANISETRON HYDROCHLORIDE) : 1 MG. It is listed in the Health Canada Drug Product Database under DIN 02385414, held by SANDOZ CANADA INCORPORATED, supplied as SOLUTION for INTRAVENOUS administration. Health Canada currently lists it as cancelled post market, status dated 01-Aug-2019. This Drug Identification Number is no longer authorized for sale in Canada, so Nexara does not supply it. The record is kept here because buyers still meet the number on old formularies, purchase orders and tender documents; Nexara can help identify an authorized alternative.
What is GRANISETRON HYDROCHLORIDE INJECTION SDZ used for?
Prevention of nausea and vomiting associated with emetogenic cancer chemotherapy, including high-dose cisplatin, in adults.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How much does Granisetron cost around the world?
Granisetron is listed on 10 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Australia publishes a ex-manufacturer; Bahrain publishes a retail (max); Hungary publishes a producer price (ex-factory). Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| South Africa | single exit price | 18 | 19 | ZAR███.██ |
| Romania | max producer price | 9 | 10 | RON███.██ |
| Saudi Arabia | public | 8 | 10 | SAR███.██ |
| United States | acquisition | 1 | 7 | USD███.██ |
| Bahrain | retail (max) | 2 | 4 | BHD███.██ |
| Australia | ex-manufacturer | 1 | 3 | AUD███.██ |
| United Kingdom | hospital | 3 | 3 | GBP███.██ |
| Hungary | producer price (ex-factory) | 2 | 2 | HUF███.██ |
| United Arab Emirates | public | 1 | 1 | AED███.██ |
| Spain | PVP con IVA (public price) | 1 | 1 | EUR███.██ |
60 pack listings across 46 brand entries and 9 price bases, refreshed 08 Sep 2026. Ranges span every Granisetron pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Granisetron in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
8 holders have a Canadian DIN containing Granisetron, across 10 DINs, of which 3 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| APOTEX INC | 1 | 1 | APO-GRANISETRON | Sourceable in Canada |
| NATCO PHARMA (CANADA) INC | 1 | 1 | NAT-GRANISETRON | Sourceable in Canada |
| OMEGA LABORATORIES LIMITED | 1 | 1 | GRANISETRON HYDROCHLORIDE INJECTION | Sourceable in Canada |
| HOFFMANN-LA ROCHE LIMITED | 2 | 0 | KYTRIL 1MG/1ML, KYTRIL TABLETS 1MG | No marketed DIN |
| SANDOZ CANADA INCORPORATED | 2 | 0 | GRANISETRON HYDROCHLORIDE INJECTION, GRANISETRON HYDROCHLORIDE INJECTION SDZ | No marketed DIN |
| HIKMA CANADA LIMITED | 1 | 0 | GRANISETRON HYDROCHLORIDE INJECTION USP | No marketed DIN |
| JAMP PHARMA CORPORATION | 1 | 0 | JAMP GRANISETRON | No marketed DIN |
| STRIDES PHARMA CANADA INC | 1 | 0 | GRANISETRON HYDROCHLORIDE INJECTION | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 1 MG |
|---|---|
| Dosage form | SOLUTION |
| Route | INTRAVENOUS |
| Pack configuration (monograph) | 1 mL ampoules (boxes of 10) and 3 mL ampoules (boxes of 1). |
| Storage | Store between 15 and 25°C. Protect from light. Stable for 24 hours at room temperature once diluted. |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Granisetron |
|---|---|
| ATC code | A04AA02 |
| AHFS class | 84:28.00 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02385414 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2385414 |
| Brand name | GRANISETRON HYDROCHLORIDE INJECTION SDZ |
| Generic / active ingredient | GRANISETRON (GRANISETRON HYDROCHLORIDE) : 1 MG |
| Market authorization holder | SANDOZ CANADA INCORPORATED |
| Health Canada schedule | Prescription |
| ATC code | A04AA02 |
| ATC anatomical main group | A — Alimentary tract and metabolism |
| ATC therapeutic subgroup | A04AA |
| Current status | CANCELLED POST MARKET |
| Status date | 01-Aug-2019 |
| Original market date | 2013-06-01 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
How is it administered?
Adults: 10 mcg/kg infused IV over 5 minutes, beginning within 30 minutes before chemotherapy. Only on day(s) when chemotherapy is given.
Included because it drives pack selection and wastage. Consult the monograph.
Contraindications
Known hypersensitivity to the drug or any component. Concomitant use with apomorphine is contraindicated due to reports of profound hypotension and loss of consciousness.
Warnings and precautions
Restricted to emetogenic chemotherapy due to rodent carcinogenicity findings. Risk of QT prolongation; caution in patients with cardiac disorders. Risk of Serotonin Syndrome.
Is Granisetron in shortage in Canada?
A Canadian shortage report is on file for a product containing this molecule: Resolved — reported by OMEGA LABORATORIES LIMITED, last seen 04 Sep 2026. A shortage on one presentation does not always affect every DIN of the molecule — the alternatives below list what else is marketed in Canada. Nexara can confirm current availability and identify substitutions or import options where permitted.
Check availability for GRANISETRON HYDROCHLORIDE INJECTION SDZ
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
3 of 10 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| APO-GRANISETRON | 1 MG | TABLET | APOTEX INC | MARKETED | 02308894 |
| GRANISETRON HYDROCHLORIDE INJECTION | 1 MG | LIQUID | OMEGA LABORATORIES LIMITED | MARKETED | 02322765 |
| NAT-GRANISETRON | 1 MG | TABLET | NATCO PHARMA (CANADA) INC | MARKETED | 02452359 |
| GRANISETRON HYDROCHLORIDE INJECTION | 1 MG | SOLUTION | STRIDES PHARMA CANADA INC | APPROVED | 02384108 |
| GRANISETRON HYDROCHLORIDE INJECTION | 1 MG | LIQUID | SANDOZ CANADA INCORPORATED | CANCELLED POST MARKET | 02304708 |
| GRANISETRON HYDROCHLORIDE INJECTION USP | 1 MG | SOLUTION | HIKMA CANADA LIMITED | APPROVED | 02558408 |
| JAMP GRANISETRON | 1 MG | TABLET | JAMP PHARMA CORPORATION | DORMANT | 02472686 |
| KYTRIL 1MG/1ML | 1 MG | LIQUID | HOFFMANN-LA ROCHE LIMITED | CANCELLED POST MARKET | 02088371 |
| KYTRIL TABLETS 1MG | 1 MG | TABLET | HOFFMANN-LA ROCHE LIMITED | CANCELLED POST MARKET | 02185881 |
2 · Same class — other molecules in ATC A04AA
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Ondansetron | ACCEL-ONDANSETRON · ACCEL-ONDANSETRON ODT · AG-ONDANSETRON · APO-ONDANSETRON · ATHENA-ONDANSETRON ODT · AURO-ONDANSETRON INJECTION · AURO-ONDANSETRON ODT · AVA-ONDANSETRON · BIO-ONDANSETRON · CCP-ONDANSETRON · DOM-ONDANSETRON · EUGIA-ONDANSETRON INJECTION · IPG-ONDANSETRON · JAMP ONDANSETRON · JAMP ONDANSETRON ODF · JAMP ONDANSETRON ODT · JAMP ONDANSETRON TABLETS · JAMP-ONDANSETRON · MAR-ONDANSETRON · MAR-ONDANSETRON ODT · MINT-ONDANSETRON · MINT-ONDANSETRON ODT · MINT-ONDANSETRON SOLUTION · MYLAN-ONDANSETRON · NAT-ONDANSETRON · NU-ONDANSETRON · ONDANSETRON · ONDANSETRON HYDROCHLORIDE DIHYDRATE INJECTION · ONDANSETRON INJECTION · ONDANSETRON INJECTION BP · ONDANSETRON INJECTION USP · ONDANSETRON INJECTION USP -(PRESERVATIVE FREE) · ONDANSETRON INJECTION USP -(WITH PRESERVATIVE) · ONDANSETRON INJECTION USP -(WITH PRESERVATIVES) · ONDANSETRON INJECTION, USP · ONDANSETRON ODT · ONDANSETRON OMEGA -(PRESERVATIVE FREE - SINGLE DOSE VIALS) · ONDANSETRON OMEGA -(WITH PRESERVATIVE - MULTIDOSE VIAL) · ONDANSETRON-ODAN · ONDISSOLVE ODF · PHL-ONDANSETRON · PMS-ONDANSETRON · PMS-ONDANSETRON ODT · PRIVA-ONDANSETRON · RAN-ONDANSETRON · RATIO-ONDANSETRON · RIVA-ONDANSETRON · SANDOZ ONDANSETRON · SEPTA-ONDANSETRON · TEVA-ONDANSETRON · VAN-ONDANSETRON · ZOFRAN · ZOFRAN INJ 2MG/ML · ZOFRAN ODT · ZOFRAN TAB 4MG · ZOFRAN TAB 8MG · ZYM-ONDANSETRON | 135 | 59 | Yes |
| Granisetron | APO-GRANISETRON · GRANISETRON HYDROCHLORIDE INJECTION · GRANISETRON HYDROCHLORIDE INJECTION SDZ · GRANISETRON HYDROCHLORIDE INJECTION USP · JAMP GRANISETRON · KYTRIL 1MG/1ML · KYTRIL TABLETS 1MG · NAT-GRANISETRON | 10 | 3 | Yes |
| Palonosetron | ALOXI | 2 | 1 | Yes |
| Palonosetron, Combinations | AKYNZEO | 1 | 1 | Yes |
| Dolasetron | ANZEMET · ANZEMET INJECTION 20 MG/ML | 3 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC A04A
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| A04AD | Aprepitant · Dronabinol · Nabilone · Other Antiemetics · Scopolamine | 29 | 14 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is GRANISETRON HYDROCHLORIDE INJECTION SDZ called?
The same molecule, Granisetron, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| Kytril | Latin | Australia, Bahrain |
| Kytril Oral | Latin | South Africa |
| Granitril Injection | Latin | South Africa |
| SANCUSO | Latin | Bahrain |
| Sancuso® | Latin | United Arab Emirates |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
Can this still be bought in Canada?
No. This Drug Identification Number is cancelled post market in Health Canada's Drug Product Database, so the product is no longer authorized for sale in Canada and Nexara does not supply it. This page is kept as a regulatory record.
If you are looking for a current equivalent, the alternatives above list every product sharing this therapeutic class, with the marketed ones first. Ask us to source an alternative
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.