COMPLERA 200 MG — DIN 02374129
EMTRICITABINE : 200 MG RILPIVIRINE (RILPIVIRINE HYDROCHLORIDE) : 25 MG TENOFOVIR DISOPROXIL FUMARATE : 300 MG · GILEAD SCIENCES CANADA INC · TABLET · wholesale supply in Canada
Health Canada status: MARKETED
What is COMPLERA?
COMPLERA 200 MG contains EMTRICITABINE : 200 MG RILPIVIRINE (RILPIVIRINE HYDROCHLORIDE) : 25 MG TENOFOVIR DISOPROXIL FUMARATE : 300 MG. It is listed in the Health Canada Drug Product Database under DIN 02374129, held by GILEAD SCIENCES CANADA INC, supplied as TABLET for ORAL administration. Health Canada currently lists it as marketed, status dated 04-Oct-2014. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is COMPLERA used for?
Complete regimen for HIV-1 infection in adults with no known NNRTI/tenofovir/FTC resistance mutations and viral load ≤ 100,000 copies/mL.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How much does Emtricitabine, Tenofovir Disoproxil And Rilpivirine cost around the world?
Emtricitabine, Tenofovir Disoproxil And Rilpivirine is listed on 6 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Austria publishes a KVP (Kassenverkaufspreis); Czechia publishes a max producer price (ex-factory); Luxembourg publishes a reimbursement. Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| Sweden | AIP (pharmacy purchase price) | 15 | 23 | SEK███.██ |
| Norway | max AUP (pharmacy retail) | 7 | 12 | NOK███.██ |
| Romania | max producer price | 7 | 11 | RON███.██ |
| Luxembourg | reimbursement | 8 | 8 | EUR███.██ |
| Austria | KVP (Kassenverkaufspreis) | 7 | 7 | EUR███.██ |
| Czechia | max producer price (ex-factory) | 1 | 4 | CZK███.██ |
65 pack listings across 45 brand entries and 6 price bases, refreshed 07 Sep 2026. Ranges span every Emtricitabine, Tenofovir Disoproxil And Rilpivirine pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 200 MG |
|---|---|
| Dosage form | TABLET |
| Route | ORAL |
| Pack configuration (monograph) | Not explicitly detailed in provided text summary, though listed as 200mg/25mg/300mg tablets. |
| Storage | Not explicitly detailed in provided text (placeholder: Store at 15-30°C per standard Gilead monographs, but null based strictly on snippet). |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Emtricitabine, Tenofovir Disoproxil And Rilpivirine |
|---|---|
| ATC code | J05AR08 |
| AHFS class | 08:18.08.20 ; 08:18.08.16 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02374129 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2374129 |
| Brand name | COMPLERA |
| Generic / active ingredient | EMTRICITABINE : 200 MG RILPIVIRINE (RILPIVIRINE HYDROCHLORIDE) : 25 MG TENOFOVIR DISOPROXIL FUMARATE : 300 MG |
| Market authorization holder | GILEAD SCIENCES CANADA INC |
| Health Canada schedule | Prescription |
| ATC code | J05AR08 |
| ATC anatomical main group | J — Anti-infectives for systemic use |
| ATC therapeutic subgroup | J05AR |
| Current status | MARKETED |
| Status date | 04-Oct-2014 |
| Original market date | 2011-10-20 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
How is it administered?
One tablet taken once daily with a meal. Not for patients with CrCl < 50 mL/min.
Included because it drives pack selection and wastage. Consult the monograph.
Contraindications
Hypersensitivity to components. Coadministration with drugs that induce CYP3A enzymes or increase gastric pH (e.g., PPIs, carbamazepine, rifampin, St. John’s wort).
Warnings and precautions
Lactic acidosis/severe hepatomegaly; post-treatment HBV exacerbation; nephrotoxicity; depressive disorders; QTc prolongation; severe skin/hypersensitivity reactions (DRESS).
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
2 · Same class — other molecules in ATC J05AR
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Tenofovir Disoproxil And Emtricitabine | AG-EMTRICITABINE / TENOFOVIR DISOPROXIL FUMARATE · APO-EMTRICITABINE-TENOFOVIR · AURO-EMTRICITABINE-TENOFOVIR · JAMP EMTRICITABINE/TENOFOVIR DISOPROXIL FUMARATE · +6 more | 10 | 9 | Yes |
| Emtricitabine, Tenofovir Disoproxil And Efavirenz | APO-EFAVIRENZ-EMTRICITABINE-TENOFOVIR · ATRIPLA · AURO-EFAVIRENZ-EMTRICITABINE-TENOFOVIR · JAMP EFAVIRENZ/EMTRICITABINE/TENOFOVIR DISOPROXIL FUMARATE · +5 more | 9 | 5 | Yes |
| Lamivudine And Abacavir | APO-ABACAVIR-LAMIVUDINE · APO-ABACAVIR-LAMIVUDINE TABLETS · AURO-ABACAVIR/LAMIVUDINE · JAMP ABACAVIR / LAMIVUDINE · +5 more | 9 | 4 | Yes |
| Zidovudine And Lamivudine | APO-LAMIVUDINE-ZIDOVUDINE · AURO-LAMIVUDINE/ZIDOVUDINE · COMBIVIR · JAMP LAMIVUDINE / ZIDOVUDINE · +1 more | 5 | 3 | Yes |
| Lopinavir And Ritonavir | KALETRA | 4 | 3 | Yes |
| Emtricitabine, Tenofovir Alafenamide And Bictegravir | BIKTARVY | 2 | 2 | Yes |
| Emtricitabine And Tenofovir Alafenamide | DESCOVY | 2 | 2 | Yes |
| Emtricitabine, Tenofovir Alafenamide And Rilpivirine | ODEFSEY | 1 | 1 | Yes |
| Darunavir And Cobicistat | PREZCOBIX | 1 | 1 | Yes |
| Emtricitabine, Tenofovir Alafenamide, Elvitegravir And Cobicistat | GENVOYA | 1 | 1 | Yes |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC J05A
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| J05AB | Acyclovir · Brincidofovir · Cidofovir · Famciclovir · Ganciclovir · +3 more | 143 | 55 |
| J05AF | Abacavir · Adefovir Dipivoxil · Didanosine · Emtricitabine · Entecavir · +7 more | 71 | 39 |
| J05AH | Neuraminidase Inhibitors · Oseltamivir · Zanamivir | 33 | 16 |
| J05AX | Baloxavir Marboxil · Bulevirtide · Enfuvirtide · Fostemsavir · Inosine Pranobex · +5 more | 19 | 14 |
| J05AE | Amprenavir · Atazanavir · Darunavir · Fosamprenavir · Indinavir · +5 more | 75 | 14 |
| J05AG | Delavirdine · Doravirine · Efavirenz · Etravirine · Nevirapine · +1 more | 22 | 10 |
| J05AJ | Cabotegravir · Dolutegravir · Elvitegravir · Raltegravir | 12 | 6 |
| J05AP | Asunaprevir · Boceprevir · Daclatasvir · Dasabuvir, Ombitasvir, Paritaprevir And Ritonavir · Elbasvir And Grazoprevir · +8 more | 22 | 6 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is COMPLERA called?
The same molecule, Emtricitabine, Tenofovir Disoproxil And Rilpivirine, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| Emtricitabine/Tenofovir disoproxil Mylan | Latin | Czechia, Norway, Sweden |
| Emtricitabine/tenofovir disoproxil Krka | Latin | Norway, Sweden |
| Eviplera | Latin | Norway |
| Descovy | Latin | Norway |
| Emtricitabine/Tenofovir disoproxil Abacus Medicine | Latin | Sweden |
| Emtricitabine/Tenofovir disoproxil Accordpharma | Latin | Norway, Sweden |
| Emtricitabine/Tenofovir disoproxil Bijon | Latin | Sweden |
| Emtricitabine/Tenofovir disoproxil Teva | Latin | Sweden |
| Emtricitabine/Tenofovir disoproxil Zentiva | Latin | Norway, Sweden |
| Odefsey | Latin | Norway |
| Oremten | Latin | Sweden |
| Truvada | Latin | Sweden |
| Emtricitabin/Tenofovirdisoproxil Orifarm | Latin | Sweden |
| Emtricitabine/Tenofovir disoproxil Glenmark | Latin | Sweden |
| Emtricitabine/Tenofovir disoproxil Sandoz | Latin | Sweden |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.