IRBESARTAN/HCTZ 12.5 MG — DIN 02372886
HYDROCHLOROTHIAZIDE : 12.5 MG IRBESARTAN : 150 MG · SANIS HEALTH INC · TABLET · wholesale supply in Canada
Health Canada status: DORMANT
What is IRBESARTAN/HCTZ?
IRBESARTAN/HCTZ 12.5 MG contains HYDROCHLOROTHIAZIDE : 12.5 MG IRBESARTAN : 150 MG. It is listed in the Health Canada Drug Product Database under DIN 02372886, held by SANIS HEALTH INC, supplied as TABLET for ORAL administration. Health Canada currently lists it as dormant, status dated 23-Jul-2026. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A). This DIN is not currently being marketed in Canada, so it is sourced to order where a compliant route exists rather than held in stock.
How much does Irbesartan And Diuretics cost around the world?
Irbesartan And Diuretics is listed on 21 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Australia publishes a ex-manufacturer; Austria publishes a KVP (Kassenverkaufspreis); Bahrain publishes a retail (max). Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| Spain | PVP con IVA (public price) | 101 | 107 | EUR███.██ |
| Australia | ex-manufacturer | 27 | 86 | AUD███.██ |
| Saudi Arabia | public | 53 | 65 | SAR███.██ |
| Sweden | AIP (pharmacy purchase price) | 15 | 60 | SEK███.██ |
| United States | acquisition | 3 | 57 | USD███.██ |
| Italy | prezzo al pubblico (classe A) | 22 | 37 | EUR███.██ |
| Greece | producer price (ex-factory) | 35 | 35 | EUR███.██ |
| South Africa | single exit price | 27 | 32 | ZAR███.██ |
| Norway | max AUP (pharmacy retail) | 8 | 27 | NOK███.██ |
| Romania | max producer price | 8 | 16 | RON███.██ |
| Luxembourg | reimbursement | 15 | 15 | EUR███.██ |
| United Arab Emirates | public | 14 | 14 | AED███.██ |
| Belgium | public | 14 | 14 | EUR███.██ |
| Bahrain | retail (max) | 6 | 14 | BHD███.██ |
| Czechia | max producer price (ex-factory) | 4 | 11 | CZK███.██ |
| Hungary | producer price (ex-factory) | 10 | 10 | HUF███.██ |
| Slovakia | categorised final price | 6 | 9 | EUR███.██ |
| Austria | KVP (Kassenverkaufspreis) | 6 | 6 | EUR███.██ |
| United Kingdom | hospital | 6 | 6 | GBP███.██ |
| Morocco | PPV (public price) | 1 | 4 | MAD███.██ |
| Iceland | max wholesale | 1 | 1 | ISK███.██ |
626 pack listings across 382 brand entries and 18 price bases, refreshed 08 Sep 2026. Ranges span every Irbesartan And Diuretics pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Irbesartan And Diuretics in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
20 holders have a Canadian DIN containing Irbesartan And Diuretics, across 67 DINs, of which 17 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| TEVA CANADA LIMITED | 9 | 3 | NTP-IRBESARTAN/HCTZ, TEVA-IRBESARTAN HCTZ, TEVA-IRBESARTAN/HCTZ | Sourceable in Canada |
| PHARMASCIENCE INC | 3 | 3 | PMS-IRBESARTAN-HCTZ | Sourceable in Canada |
| PRO DOC LIMITEE | 3 | 3 | IRBESARTAN-HCTZ | Sourceable in Canada |
| SANDOZ CANADA INCORPORATED | 3 | 3 | SANDOZ IRBESARTAN HCT | Sourceable in Canada |
| SIVEM PHARMACEUTICALS ULC | 3 | 3 | IRBESARTAN HCT | Sourceable in Canada |
| SANOFI-AVENTIS CANADA INC | 3 | 2 | AVALIDE | Sourceable in Canada |
| ACTAVIS PHARMA COMPANY | 6 | 0 | ACT IRBESARTAN/HCT, IRBESARTAN/HCT | No marketed DIN |
| JUBILANT GENERICS LIMITED | 3 | 0 | IRBESARTAN AND HYDROCHLOROTHIAZIDE | No marketed DIN |
| MINT PHARMACEUTICALS INC | 3 | 0 | MINT-IRBESARTAN/HCTZ | No marketed DIN |
| MYLAN PHARMACEUTICALS ULC | 3 | 0 | MYLAN-IRBESARTAN HCTZ | No marketed DIN |
| RANBAXY PHARMACEUTICALS CANADA INC. | 3 | 0 | RAN-IRBESARTAN HCTZ | No marketed DIN |
| SANIS HEALTH INC | 3 | 0 | IRBESARTAN/HCTZ | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 12.5 MG |
|---|---|
| Dosage form | TABLET |
| Route | ORAL |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Irbesartan And Diuretics |
|---|---|
| ATC code | C09DA04 |
| AHFS class | 84:80.00 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02372886 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2372886 |
| Brand name | IRBESARTAN/HCTZ |
| Generic / active ingredient | HYDROCHLOROTHIAZIDE : 12.5 MG IRBESARTAN : 150 MG |
| Market authorization holder | SANIS HEALTH INC |
| Health Canada schedule | Prescription |
| ATC code | C09DA04 |
| ATC anatomical main group | C — Cardiovascular system |
| ATC therapeutic subgroup | C09DA |
| Current status | DORMANT |
| Status date | 23-Jul-2026 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
Is Irbesartan And Diuretics in shortage in Canada?
A Canadian shortage report is on file for a product containing this molecule: Resolved — reported by SANIS HEALTH INC, last seen 09 Sep 2026. A shortage on one presentation does not always affect every DIN of the molecule — the alternatives below list what else is marketed in Canada. Nexara can confirm current availability and identify substitutions or import options where permitted.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
17 of 67 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| AVALIDE | 150 MG | TABLET | SANOFI-AVENTIS CANADA INC | MARKETED | 02241818 |
| AVALIDE | 12.5 MG | TABLET | SANOFI-AVENTIS CANADA INC | MARKETED | 02241819 |
| IRBESARTAN HCT | 300 MG | TABLET | SIVEM PHARMACEUTICALS ULC | MARKETED | 02385333 |
| IRBESARTAN HCT | 150 MG | TABLET | SIVEM PHARMACEUTICALS ULC | MARKETED | 02385317 |
| IRBESARTAN HCT | 12.5 MG | TABLET | SIVEM PHARMACEUTICALS ULC | MARKETED | 02385325 |
| IRBESARTAN-HCTZ | 150 MG | TABLET | PRO DOC LIMITEE | MARKETED | 02365162 |
| IRBESARTAN-HCTZ | 300 MG | TABLET | PRO DOC LIMITEE | MARKETED | 02365170 |
| IRBESARTAN-HCTZ | 25 MG | TABLET | PRO DOC LIMITEE | MARKETED | 02365189 |
| PMS-IRBESARTAN-HCTZ | 150 MG | TABLET | PHARMASCIENCE INC | MARKETED | 02328518 |
| PMS-IRBESARTAN-HCTZ | 300 MG | TABLET | PHARMASCIENCE INC | MARKETED | 02328534 |
2 · Same class — other molecules in ATC C09DA
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Valsartan And Diuretics | APO-VALSARTAN/HCTZ · AURO-VALSARTAN HCT · AVA-VALSARTAN HCT · DIOVAN-HCT · +8 more | 63 | 32 | Yes |
| Candersartan And Diuretics | ACCEL-CANDESARTAN/HCTZ · ACT CANDESARTAN/HCT · AG-CANDESARTAN HCT · APO-CANDESARTAN/HCTZ · +16 more | 49 | 22 | Yes |
| Telmisartan And Diuretics | ACH-TELMISARTAN HCTZ · ACT TELMISARTAN/HCT · AG TELMISARTAN-HCT · ALEMBIC-TELMISARTAN/HCTZ · +17 more | 42 | 22 | Yes |
| Losartan And Diuretics | ACT LOSARTAN/HCT · AG-LOSARTAN HCTZ · APO-LOSARTAN/HCTZ · AURO-LOSARTAN HCT · +19 more | 53 | 21 | Yes |
| Olmesartan Medoxomil And Diuretics | ACH-OLMESARTAN HCTZ · AG-OLMESARTAN HCTZ · APO-OLMESARTAN/HCTZ · AURO-OLMESARTAN HCTZ · +11 more | 45 | 21 | Yes |
| Irbesartan And Diuretics | ACT IRBESARTAN/HCT · AG-IRBESARTAN HCTZ · APO-IRBESARTAN/HCTZ · AURO-IRBESARTAN HCT · +19 more | 67 | 17 | Yes |
| Azilsartant Medoximil And Diuretics | EDARBYCLOR | 3 | 2 | Yes |
| Eprosartan And Diuretics | TEVETEN PLUS | 1 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC C09D
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| C09DB | Telmisartan And Amlodipine | 12 | 8 |
| C09DX | Valsartan And Sacubitril | 6 | 6 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is IRBESARTAN/HCTZ called?
The same molecule, Irbesartan And Diuretics, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| Aprovel | Latin | Bahrain, Iceland, Morocco, Norway, Sweden |
| CoAprovel | Latin | Bahrain, Norway, Sweden |
| Irbesartan Sandoz | Latin | Australia, Norway, Sweden |
| Karvea | Latin | Australia, Sweden |
| Irbesartan/Hydroklortiazid Actavis | Latin | Norway, Sweden |
| APO-Irbesartan | Latin | Australia |
| APO-Irbesartan HCTZ | Latin | Australia |
| AVSARTAN | Latin | Australia |
| Blooms Irbesartan | Latin | Australia |
| Ifirmasta | Latin | Czechia, Sweden |
| Irbesartan Actavis | Latin | Norway, Sweden |
| IRBESARTAN-WGR | Latin | Australia |
| Irbesartan/HCT Sandoz | Latin | Australia |
| Ifirmacombi | Latin | Czechia, Sweden |
| Irbesartan Hydrochlorothiazide Zentiva | Latin | Sweden |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
This DIN is dormant — it holds a Health Canada authorization but is not currently being marketed in Canada, so it cannot simply be ordered from Canadian stock. Where a patient need exists, supply may be possible through exceptional importation or the Special Access Programme, subject to Health Canada's requirements and the prescriber's application. Nexara can advise on the route and on marketed alternatives.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.