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COLGATE TOTAL ADVANCED HEALTH GUM DEFENSE 0.300 % — DIN 02364786

TRICLOSAN : 0.300 % SODIUM FLUORIDE : 0.243 % · COLGATE-PALMOLIVE CANADA INC · TOOTHPASTE · wholesale supply in Canada

Health Canada status: CANCELLED POST MARKET

What is COLGATE TOTAL ADVANCED HEALTH GUM DEFENSE?

COLGATE TOTAL ADVANCED HEALTH GUM DEFENSE 0.300 % contains TRICLOSAN : 0.300 % SODIUM FLUORIDE : 0.243 %. It is listed in the Health Canada Drug Product Database under DIN 02364786, held by COLGATE-PALMOLIVE CANADA INC, supplied as TOOTHPASTE for DENTAL administration. Health Canada currently lists it as cancelled post market, status dated 01-Aug-2019. This Drug Identification Number is no longer authorized for sale in Canada, so Nexara does not supply it. The record is kept here because buyers still meet the number on old formularies, purchase orders and tender documents; Nexara can help identify an authorized alternative.

What is COLGATE TOTAL ADVANCED HEALTH GUM DEFENSE used for?

Prevention of cavities, plaque, gingivitis, and calculus.

Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.

Is there a generic Sodium Fluoride, Combinations in Canada, and who makes it?

Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.

19 holders have a Canadian DIN containing Sodium Fluoride, Combinations, across 38 DINs, of which 0 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.

Market authorization holderDINsMarketedBrand namesPosition
COLGATE-PALMOLIVE CANADA INC80COLGATE TARTAR CONTROL MINT GEL TPT - TUBE, COLGATE TARTAR CONTROL MINT TPT - TUBE, COLGATE TOTAL - ADVANCED HEALTH, COLGATE TOTAL 12H PRO-SHIELD, COLGATE TOTAL ADVANCED HEALTH DAILY REPAIR, +3 moreNo marketed DIN
ORAL-B LABORATORIES, A DIV. OF PROCTER & GAMBLE INC50ORAL B ANTI-BACTERIAL WITH FLUORIDE, ORAL-B ANTI-BACTERIAL WITH FLUORIDE, ORAL-B ANTIBACTERIAL WITH FLUORIDE ALC.FREE, ORAL-B SENSITIVE WITH FLUORIDE TOOTHPASTE, SENSITIVE WITH FLUORIDE TPTNo marketed DIN
LACLEDE INC.40TOPICAL FLUORIDE FOAM BUBBLE GUM FLAVOUR, TOPICAL FLUORIDE FOAM KOALA BERRY FLAVOUR, TOPICAL FLUORIDE FOAM TYRANNA GRAPE FLAVOUR, TOPICAL FLUORIDE FOAM WITCHY CANDY MINTNo marketed DIN
MEDICAL PRODUCTS LABORATORIES INC.40ZIROXIDE COARSE GRIT 1.23% FLUORIDE, ZIROXIDE COARSE PASTE 1.23% FLUORIDE, ZIROXIDE MEDIUM FINE GRIT 1.23% FLUORIDE, ZIROXIDE MEDIUM FINE PASTE 1.23% FLUORIDENo marketed DIN
PDT IMAGE INC. DBA PRO-DENTEC CANADA30ORTHOCHECK, PRO-DENTX COMFORT DENTIN DESENSITIZER, THIXOTROPIC ACIDULATED PHOS. FLUOR. TOP. GELNo marketed DIN
DENTSPLY INTERNATIONAL10NUPRO APF TOPICAL GELNo marketed DIN
GERMIPHENE CORPORATION10ORO MIN REMINERALIZING SOLNNo marketed DIN
GLAXOSMITHKLINE CONSUMER HEALTHCARE ULC10SENSODYNE-F MINT TOOTHPASTENo marketed DIN
JOHN O. BUTLER COMPANY10BUTLER PROTECT ONE MINUTE APF FLUORIDE GELNo marketed DIN
LORNAMEAD BRANDS (CANADA) INC.10NATURAL WHITE PRO SENSITIVE CLEAN AND POLISH TOOTHTPASTENo marketed DIN
LORVIC CORP10LORVIC DESENSITIZERNo marketed DIN
NATIONAL CARE PRODUCTS LTD.10FLUORIDE MOUTHWASHNo marketed DIN

Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.

How is it supplied and stored?

Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.

Strength on the label0.300 %
Dosage formTOOTHPASTE
RouteDENTAL
Pack configuration (monograph)85 and 170 mL tubes.
StorageStore at room temperature (15 – 30 °C).

Pack detail is kept as a regulatory record. This DIN is no longer authorized for sale in Canada, so Nexara does not quote this pack.

Substance and classification

Active substanceSodium Fluoride, Combinations
ATC codeA01AA51
AHFS class34:00.00
Biosimilar biologicNo

Health Canada record and identifiers

The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.

DIN (8-digit, as used in ordering)02364786
DIN (unpadded, as printed on some documents)2364786
Brand nameCOLGATE TOTAL ADVANCED HEALTH GUM DEFENSE
Generic / active ingredientTRICLOSAN : 0.300 % SODIUM FLUORIDE : 0.243 %
Market authorization holderCOLGATE-PALMOLIVE CANADA INC
Health Canada scheduleNON-PRESCRIPTION DRUGS
ATC codeA01AA51
ATC anatomical main groupA — Alimentary tract and metabolism
ATC therapeutic subgroupA01AA
Current statusCANCELLED POST MARKET
Status date01-Aug-2019
Original market date2011-07-25 00:00:00
Status sourceLive Health Canada DPD sync

Verify on the primary sources

Health Canada DPD record Approved product monograph (PDF)

How is it administered?

For adults and children over 12: apply a ribbon of toothpaste across the head of toothbrush; brush teeth at least twice daily. Use in conjunction with professional exams and flossing.

Included because it drives pack selection and wastage. Consult the monograph.

Contraindications

Persons with known sensitivities to any of these ingredients (standard toothpaste ingredients plus triclosan and fluoride) should avoid using the product.

Warnings and precautions

There are no warnings or precautions required for this product. Keep out of reach of children (implied by overdose section).

Is Sodium Fluoride, Combinations in shortage in Canada?

A Canadian shortage report is on file for a product containing this molecule: Active — reported by SANDOZ CANADA INCORPORATED, last seen 09 Sep 2026. A shortage on one presentation does not always affect every DIN of the molecule — the alternatives below list what else is marketed in Canada. Nexara can confirm current availability and identify substitutions or import options where permitted.

Check availability for COLGATE TOTAL ADVANCED HEALTH GUM DEFENSE

What can be used instead?

Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.

1 · Same molecule, other Canadian presentations

0 of 38 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.

ProductStrengthFormHolderHealth Canada statusDIN
BUTLER PROTECT ONE MINUTE APF FLUORIDE GEL0.17 %GELJOHN O. BUTLER COMPANYCANCELLED POST MARKET02236870
CEPACOL MOUTHWASH WITH FLUORIDE0.5 MGMOUTHWASH/GARGLECOMBE INCORPORATEDCANCELLED POST MARKET02099365
CEPACOL PEPPERMINT MOUTHWASH WITH FLUORIDE0.5 MGMOUTHWASH/GARGLE ; LIQUIDSMITHKLINE BEECHAM CONSUMER HEALTHCARE, DIVISION OF SMITHKLINE BEECHAM INC.CANCELLED POST MARKET02099381
COLGATE TARTAR CONTROL MINT GEL TPT - TUBE.243 %TOOTHPASTECOLGATE-PALMOLIVE CANADA INCCANCELLED POST MARKET02018799
COLGATE TARTAR CONTROL MINT TPT - TUBE.243 %TOOTHPASTECOLGATE-PALMOLIVE CANADA INCCANCELLED POST MARKET02018802
COLGATE TOTAL - ADVANCED HEALTH0.3 %TOOTHPASTECOLGATE-PALMOLIVE CANADA INCCANCELLED POST MARKET02285568
COLGATE TOTAL 12H PRO-SHIELD0.05 %MOUTHWASH/GARGLECOLGATE-PALMOLIVE CANADA INCCANCELLED POST MARKET02401991
COLGATE TOTAL ADVANCED HEALTH DAILY REPAIR5 %TOOTHPASTECOLGATE-PALMOLIVE CANADA INCCANCELLED POST MARKET02440679
COLGATE TOTAL ADVANCED HEALTH SENSITIVE5 %TOOTHPASTECOLGATE-PALMOLIVE CANADA INCCANCELLED POST MARKET02373254
COLGATE TOTAL TPT0.243 %TOOTHPASTECOLGATE-PALMOLIVE CANADA INCCANCELLED POST MARKET02044730

2 · Same class — other molecules in ATC A01AA

MoleculeCanadian brandsDINsMarketedSourceable
Sodium Fluoride0.2% SODIUM FLUORIDE WEEKLY ORAL RINSE · 1.1% NEUTRAL SODIUM FLUORIDE TOPICAL GEL · ACT FLUORIDE · AIM - TPT GEL 0.23% · +105 more1090Not in Canada
Sodium MonofluorophosphateAIM · AQUAFRESH ADVANCED CLEAN MINT TOOTHPASTE (PUMP) · AQUAFRESH ADVANCED EXTRA FRESH TOOTHPASTE · AQUAFRESH BAKING SODA CLEAN TASTE · +42 more460Not in Canada
Sodium Fluoride, CombinationsBUTLER PROTECT ONE MINUTE APF FLUORIDE GEL · CEPACOL MOUTHWASH WITH FLUORIDE · CEPACOL PEPPERMINT MOUTHWASH WITH FLUORIDE · COLGATE TARTAR CONTROL MINT GEL TPT - TUBE · +34 more380Not in Canada
Stannous Fluoride0.4% STANNOUS FLUORIDE BRUSH ON GEL · 0.63% STANNOUS FLUOR. ORAL RINSE CONCENTRATE · 1.64% STAN. FLUOR. OFFICE RINSE CONCENTRATE · 3.28% STANNOUS FLUOR. IRRIGATION CONCENTRATE · +15 more190Not in Canada
Sodium Monofluorophosphate, CombinationsNATURAL WHITE WHT. TPT SENS.TEETH-FRESH MINT · REMBRANDT WHITENING TOOTHPASTE FOR SENSITIVE TEETH · SENSODYNE-F FLUORIDE TOOTHPASTE · TOPOL PLUS WHITENING TPT FOR SENSITIVE TEETH · +2 more60Not in Canada
Caries Prophylactic AgentsFLUOR PROTECTOR · TRIDENT ADVANTAGE GUM · XYLIFRESH 100 (PEPPERMINT) - GUM 827 MG · XYLIFRESH 100 (SPEARMINT) - GUM40Not in Canada
Combination (Caries Prophylactic Agents)ACIDULATED PHOSPHATE FLUORIDE ORAL SOLUTION · PASCAL PUFF · PDF GEL 1.24% · PERFECT CHOICE 0.717% ROOT AND DENTIN DESENS40Not in Canada

A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.

3 · Adjacent classes in ATC A01A

ATC subgroupMoleculesDINsMarketed
A01ABAntiinfectives For Local Oral Treatment · Chlorhexidine · Domiphen · Doxycycline · Hexetidine · +3 more4411
A01ADAmlexanox · Benzydamine · Epinephrine · Epinephrine, Combinations · Other Agents For Local Oral Treatment · +1 more1465
A01ACCorticosteroids For Local Oral Treatment · Dexamethasone, Combinations * · Prednisolone, Combinations · Triamcinolone71

Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.

Can this still be bought in Canada?

No. This Drug Identification Number is cancelled post market in Health Canada's Drug Product Database, so the product is no longer authorized for sale in Canada and Nexara does not supply it. This page is kept as a regulatory record.

If you are looking for a current equivalent, the alternatives above list every product sharing this therapeutic class, with the marketed ones first. Ask us to source an alternative

Ordering questions

Who can buy this from Nexara?

Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.

Is there a minimum order?

Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.

What is the lead time?

Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.

Why is there no price on this page?

Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.

Can Nexara supply this for a clinical trial?

Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.

Sources and disclaimer

Product data sourced from the Health Canada Drug Product Database and the approved product monograph (PDF). Health Canada status reconciled against the live DPD sync. Last reviewed 10 Sep 2026.

Nothing on this page is medical advice. Nexara Health is a licensed wholesale distributor and supplies licensed entities only; consumer orders are routed to a partner pharmacy. Alternatives tables describe supply, not clinical equivalence.

Health Canada Drug Product Database (DPD), DIN 02364786. Last reviewed 2026-09-10. Nexara Health is a licensed wholesaler and supplies licensed entities only; consumer orders are routed to a partner pharmacy.