TARGIN 40 MG — DIN 02339625
OXYCODONE HYDROCHLORIDE : 40 MG NALOXONE HYDROCHLORIDE : 20 MG · PURDUE PHARMA · TABLET (EXTENDED-RELEASE) · wholesale supply in Canada
Health Canada status: MARKETED
What is TARGIN?
TARGIN 40 MG contains OXYCODONE HYDROCHLORIDE : 40 MG NALOXONE HYDROCHLORIDE : 20 MG. It is listed in the Health Canada Drug Product Database under DIN 02339625, held by PURDUE PHARMA, supplied as TABLET (EXTENDED-RELEASE) for ORAL administration. Health Canada currently lists it as marketed, status dated 05-Oct-2010. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is TARGIN used for?
Management of severe pain requiring daily, continuous, long-term opioid treatment where alternatives are inadequate; relief of opioid-induced constipation (OIC). Not for as-needed use.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How much does Oxycodone And Naloxone cost around the world?
Oxycodone And Naloxone is listed on 5 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Australia publishes a ex-manufacturer; Greece publishes a producer price (ex-factory); Hungary publishes a producer price (ex-factory). Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| Australia | ex-manufacturer | 32 | 108 | AUD███.██ |
| United Kingdom | hospital | 12 | 12 | GBP███.██ |
| Hungary | producer price (ex-factory) | 10 | 10 | HUF███.██ |
| United States | acquisition | 2 | 9 | USD███.██ |
| Greece | producer price (ex-factory) | 2 | 2 | EUR███.██ |
141 pack listings across 58 brand entries and 4 price bases, refreshed 08 Sep 2026. Ranges span every Oxycodone And Naloxone pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Oxycodone And Naloxone in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
Only one market authorization holder has a Canadian DIN containing Oxycodone And Naloxone — 4 DINs, of which 4 are currently marketed. There is no second Canadian source today, so a supply interruption on this holder has no domestic substitute at the same molecule.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| PURDUE PHARMA | 4 | 4 | TARGIN | Sourceable in Canada |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 40 MG |
|---|---|
| Dosage form | TABLET (EXTENDED-RELEASE) |
| Route | ORAL |
| Pack configuration (monograph) | Not explicitly detailed in text provided beyond tablet descriptions (5/2.5 mg, 10/5 mg, 20/10 mg, 40/20 mg). |
| Storage | Not specified in the provided text (refer to section 11). |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Oxycodone And Naloxone |
|---|---|
| ATC code | N02AA55 |
| AHFS class | 28:10.00 ; 28:08.08 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02339625 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2339625 |
| Brand name | TARGIN |
| Generic / active ingredient | OXYCODONE HYDROCHLORIDE : 40 MG NALOXONE HYDROCHLORIDE : 20 MG |
| Market authorization holder | PURDUE PHARMA |
| Health Canada schedule | NARCOTICS (CDSA I) |
| ATC code | N02AA55 |
| ATC anatomical main group | N — Nervous system |
| ATC therapeutic subgroup | N02AA |
| Current status | MARKETED |
| Status date | 05-Oct-2010 |
| Original market date | 2010-10-05 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
How is it administered?
Swallow whole; do not crush/chew. Initial: 10/5 mg every 12 hours. Max daily dose: 80 mg oxycodone/40 mg naloxone. Titrate every 1-2 days. Taper gradually to discontinue.
Included because it drives pack selection and wastage. Consult the monograph.
Contraindications
Hypersensitivity; GI obstruction/ileus; acute/severe asthma; respiratory depression; severe CNS depression; head injury; MAO inhibitors; pregnancy/breast-feeding; moderate-severe hepatic impairment.
Warnings and precautions
Risk of addiction, abuse, misuse, and fatal overdose. Life-threatening respiratory depression. Accidental ingestion can be fatal. Concomitant use with benzodiazepines/alcohol is dangerous.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
4 of 4 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| TARGIN | 5 MG | TABLET (EXTENDED-RELEASE) | PURDUE PHARMA | MARKETED | 02339609 |
| TARGIN | 10 MG | TABLET (EXTENDED-RELEASE) | PURDUE PHARMA | MARKETED | 02339617 |
| TARGIN | 2.50 MG | TABLET (EXTENDED-RELEASE) | PURDUE PHARMA | MARKETED | 02387425 |
2 · Same class — other molecules in ATC N02AA
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Morphine | BAR-MORPHINE SR · DOLORAL SIROP · KADIAN · M-EDIAT · +86 more | 172 | 56 | Yes |
| Hydromorphone | APO-HYDROMORPHONE · APO-HYDROMORPHONE CR · BAR-HYDROMORPHONE CR · DILAUDID · +40 more | 85 | 34 | Yes |
| Oxycodone | ACT OXYCODONE CR · APO-OXYCODONE CR · OXY.IR · OXYCODONE · +16 more | 68 | 28 | Yes |
| Codein, Combinations With Psycholeptics | APO-BUTALBITAL-ACETYLSALICYLIC ACID-CAFFEINE-CODEINE-C 1/2 · APO-BUTALBITAL-ACETYLSALICYLIC ACID-CAFFEINE-CODEINE-C 1/4 · FIORINAL-C 1/2 · FIORINAL-C 1/4 · +13 more | 17 | 6 | Yes |
| Oxycodone And Naloxone | TARGIN | 4 | 4 | Yes |
| Codeine, Combinations Excl. Psycholeptics | AXACET-C1/8 · AXISAL-C1/8 · METHOXACET-C 1/8 · METHOXISAL-C 1/2 · +21 more | 25 | 1 | Yes |
| Natural Opium Alkaloids | NUMORPHAN INJECTION 1.5MG/ML · NUMORPHAN SUPPOSITORY 5MG · OPANA ER | 6 | 0 | Not in Canada |
| Opium | OPIUM TEINTURE | 1 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC N02A
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| N02AX | Tapentadol · Tramadol | 41 | 30 |
| N02AJ | Codeine And Acetylsalicylic Acid · Codeine And Paracetamol · Hydrocodone And Ibuprofen · Oxycodone And Acetylsalicylic Acid · Oxycodone And Paracetamol · +1 more | 137 | 21 |
| N02AB | Fentanyl · Pethidine | 105 | 17 |
| N02AE | Buprenorphine | 15 | 4 |
| N02AF | Butorphanol · Nalbufine | 5 | 2 |
| N02AG | Opioids In Comb With Antispasmodics | 3 | 0 |
| N02AD | Pentazocine | 3 | 0 |
| N02AC | Dextropropoxyphene · Dextropropoxyphene, Comb Excl Psycholept | 7 | 0 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is TARGIN called?
The same molecule, Oxycodone And Naloxone, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| OxyContin | Latin | Australia |
| OxyNorm | Latin | Australia |
| Oxycodone BNM | Latin | Australia |
| Oxycodone Sandoz | Latin | Australia |
| ENDONE | Latin | Australia |
| Oxycodone Viatris | Latin | Australia |
| Mayne Pharma Oxycodone IR | Latin | Australia |
| Oxyndone | Latin | Australia |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.