TARGIN 40 MG
OXYCODONE HYDROCHLORIDE : 40 MG NALOXONE HYDROCHLORIDE : 20 MG · DIN 02339625 · PURDUE PHARMA
Health Canada status: MARKETED
What is TARGIN?
TARGIN 40 MG contains OXYCODONE HYDROCHLORIDE : 40 MG NALOXONE HYDROCHLORIDE : 20 MG. It is listed in the Health Canada Drug Product Database under DIN 02339625, held by PURDUE PHARMA, supplied as TABLET (EXTENDED-RELEASE) for ORAL administration. Health Canada currently lists it as marketed, status dated 05-Oct-2010. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is TARGIN used for?
Management of severe pain requiring daily, continuous, long-term opioid treatment where alternatives are inadequate; relief of opioid-induced constipation (OIC). Not for as-needed use.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
Product details and regulatory record
| DIN | 02339625 |
|---|---|
| Brand name | TARGIN |
| Generic / active ingredient | OXYCODONE HYDROCHLORIDE : 40 MG NALOXONE HYDROCHLORIDE : 20 MG |
| Manufacturer | PURDUE PHARMA |
| Strength | 40 MG |
| Dosage form | TABLET (EXTENDED-RELEASE) |
| Route of administration | ORAL |
| Schedule | NARCOTICS (CDSA I) |
| ATC code | N02AA55 OXYCODONE AND NALOXONE |
| AHFS class | 28:10.00 ; 28:08.08 |
| Biosimilar | No |
| Health Canada status | MARKETED |
| Status date | 05-Oct-2010 |
| Original market date | 2010-10-05 00:00:00 |
How is it administered?
Swallow whole; do not crush/chew. Initial: 10/5 mg every 12 hours. Max daily dose: 80 mg oxycodone/40 mg naloxone. Titrate every 1-2 days. Taper gradually to discontinue.
Included because it drives pack selection and wastage. Consult the monograph.
How is it stored and handled?
Not specified in the provided text (refer to section 11).
How is it supplied?
Not explicitly detailed in text provided beyond tablet descriptions (5/2.5 mg, 10/5 mg, 20/10 mg, 40/20 mg).
Contraindications
Hypersensitivity; GI obstruction/ileus; acute/severe asthma; respiratory depression; severe CNS depression; head injury; MAO inhibitors; pregnancy/breast-feeding; moderate-severe hepatic impairment.
Warnings and precautions
Risk of addiction, abuse, misuse, and fatal overdose. Life-threatening respiratory depression. Accidental ingestion can be fatal. Concomitant use with benzodiazepines/alcohol is dangerous.
What can be used instead?
Other Canadian products sharing ATC code N02AA55 OXYCODONE AND NALOXONE. 4 of 4 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.
| Product | Strength | Form | Manufacturer | Health Canada status | DIN |
|---|---|---|---|---|---|
| TARGIN | 10 MG | TABLET (EXTENDED-RELEASE) | PURDUE PHARMA | MARKETED | DIN 02339617 |
| TARGIN | 2.50 MG | TABLET (EXTENDED-RELEASE) | PURDUE PHARMA | MARKETED | DIN 02387425 |
| TARGIN | 5 MG | TABLET (EXTENDED-RELEASE) | PURDUE PHARMA | MARKETED | DIN 02339609 |
Who else supplies OXYCODONE AND NALOXONE worldwide?
Nexara tracks national medicine registries and published price lists across multiple markets. OXYCODONE AND NALOXONE appears in 240 registered pack listings across 9 markets, published on 7 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.
Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.