SANDOZ CYCLOSPORINE 25 MG — DIN 02247073
CYCLOSPORINE : 25 MG · SANDOZ CANADA INCORPORATED · CAPSULE · wholesale supply in Canada
Health Canada status: MARKETED
What is SANDOZ CYCLOSPORINE?
SANDOZ CYCLOSPORINE 25 MG contains CYCLOSPORINE : 25 MG. It is listed in the Health Canada Drug Product Database under DIN 02247073, held by SANDOZ CANADA INCORPORATED, supplied as CAPSULE for ORAL administration. Health Canada currently lists it as marketed, status dated 18-Feb-2006. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is SANDOZ CYCLOSPORINE used for?
Sandoz Cyclosporine (cyclosporine) is indicated in the prevention of graft rejection following solid organ transplantation and in the treatment of transplant rejection in patients previously receiving other immunosuppressive agents. Sandoz Cyclosporine is indicated in the prevention of graft rejection following bone marrow transplantation and the prevention or treatment of graft-versus-host disease (GVHD). Sandoz Cyclosporine is indicated for the treatment of severe psoriasis in patients for whom conventional therapy is ineffective or inappropriate. Sandoz Cyclosporine is also indicated for the treatment of severe active rheumatoid arthritis in patients for whom classical slow-acting antirheumatic agents are inappropriate or ineffective. Sandoz Cyclosporine is indicated in adults and children for steroid dependent and steroid resistant nephrotic syndrome due to glomerular diseases such as minimal change nephropathy, focal and segmental glomerulosclerosis, or membranous glomerulonephritis. Sandoz Cyclosporine can be used to induce remissions and to maintain them. It can also be used for maintenance of steroid induced remissions, allowing withdrawal of, or reduction in the dosage of steroids.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How much does Ciclosporin cost around the world?
Ciclosporin is listed on 11 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Australia publishes a ex-manufacturer; Austria publishes a KVP (Kassenverkaufspreis); Bahrain publishes a retail (max). Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| Australia | ex-manufacturer | 10 | 48 | AUD███.██ |
| Saudi Arabia | public | 11 | 13 | SAR███.██ |
| Greece | producer price (ex-factory) | 10 | 10 | EUR███.██ |
| Iceland | max wholesale | 5 | 10 | ISK███.██ |
| United Arab Emirates | public | 6 | 7 | AED███.██ |
| South Africa | single exit price | 4 | 7 | ZAR███.██ |
| Bahrain | retail (max) | 2 | 6 | BHD███.██ |
| Romania | max producer price | 3 | 5 | RON███.██ |
| Austria | KVP (Kassenverkaufspreis) | 2 | 2 | EUR███.██ |
| Czechia | max producer price (ex-factory) | 1 | 1 | CZK███.██ |
| Hungary | producer price (ex-factory) | 1 | 1 | HUF███.██ |
110 pack listings across 55 brand entries and 9 price bases, refreshed 08 Sep 2026. Ranges span every Ciclosporin pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Ciclosporin in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
5 holders have a Canadian DIN containing Ciclosporin, across 18 DINs, of which 9 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| NOVARTIS PHARMACEUTICALS CANADA INC | 6 | 6 | NEORAL, SANDIMMUNE I.V. | Sourceable in Canada |
| SANDOZ CANADA INCORPORATED | 4 | 3 | CYCLOSPORINE, SANDOZ CYCLOSPORINE | Sourceable in Canada |
| SANDOZ CANADA INC | 4 | 0 | SANDIMMUNE CAP 50MG, SANDIMMUNE ORAL SOL 100MG/ML, SANDIMMUNE SOFT GELATIN CAP 100MG, SANDIMMUNE SOFT GELATINE CAP 25MG | No marketed DIN |
| EDENBRIDGE PHARMACEUTICALS, LLC | 3 | 0 | CYCLOSPORINE | No marketed DIN |
| APOTEX INC | 1 | 0 | APO-CYCLOSPORINE ORAL SOLUTION | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 25 MG |
|---|---|
| Dosage form | CAPSULE |
| Route | ORAL |
| Pack configuration (monograph) | Sandoz Cyclosporine 25 mg are supplied in boxes of 30 capsules containing 3 full aluminum blister strips of 10 capsules. Sandoz Cyclosporine 50 mg are supplied in boxes of 30 capsules containing 3 full aluminum blister strips of 10 capsules. Sandoz Cyclosporine 100 mg are supplied in boxes of 30 capsules containing 3 full aluminum blister strips of 10 capsules. |
| Storage | null |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Ciclosporin |
|---|---|
| ATC code | L04AD01 |
| AHFS class | 90:28.28.92 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02247073 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2247073 |
| Brand name | SANDOZ CYCLOSPORINE |
| Generic / active ingredient | CYCLOSPORINE : 25 MG |
| Market authorization holder | SANDOZ CANADA INCORPORATED |
| Health Canada schedule | Prescription |
| ATC code | L04AD01 |
| ATC anatomical main group | L — Antineoplastic and immunomodulating agents |
| ATC therapeutic subgroup | L04AD |
| Current status | MARKETED |
| Status date | 18-Feb-2006 |
| Original market date | 2006-10-18 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
9 of 18 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| NEORAL | 10 MG | CAPSULE | NOVARTIS PHARMACEUTICALS CANADA INC | MARKETED | 02237671 |
| NEORAL | 50 MG | CAPSULE | NOVARTIS PHARMACEUTICALS CANADA INC | MARKETED | 02150662 |
| NEORAL | 100 MG | CAPSULE | NOVARTIS PHARMACEUTICALS CANADA INC | MARKETED | 02150670 |
| NEORAL | 25 MG | CAPSULE | NOVARTIS PHARMACEUTICALS CANADA INC | MARKETED | 02150689 |
| NEORAL | 100 MG | SOLUTION | NOVARTIS PHARMACEUTICALS CANADA INC | MARKETED | 02150697 |
| SANDIMMUNE I.V. | 50 MG | SOLUTION | NOVARTIS PHARMACEUTICALS CANADA INC | MARKETED | 00593257 |
| SANDOZ CYCLOSPORINE | 50 MG | CAPSULE | SANDOZ CANADA INCORPORATED | MARKETED | 02247074 |
| SANDOZ CYCLOSPORINE | 100 MG | CAPSULE | SANDOZ CANADA INCORPORATED | MARKETED | 02242821 |
| APO-CYCLOSPORINE ORAL SOLUTION | 100 MG | SOLUTION | APOTEX INC | CANCELLED POST MARKET | 02244324 |
| CYCLOSPORINE | 50 MG | CAPSULE | EDENBRIDGE PHARMACEUTICALS, LLC | DORMANT | 02495821 |
2 · Same class — other molecules in ATC L04AD
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Tacrolimus | ACH-TACROLIMUS · ADVAGRAF · APO-TACROLIMUS · APO-TACROLIMUS CAPSULES · +6 more | 31 | 21 | Yes |
| Ciclosporin | APO-CYCLOSPORINE ORAL SOLUTION · CYCLOSPORINE · NEORAL · SANDIMMUNE CAP 50MG · +5 more | 18 | 9 | Yes |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC L04A
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| L04AX | Azathioprine · Dimethyl Fumarate · Lenalidomide · Methotrexate · Other Immunosuppressants · +3 more | 191 | 124 |
| L04AC | Anakinra · Basiliximab · Bimekizumab · Brodalumab · Canakinumab · +13 more | 85 | 75 |
| L04AB | Adalimumab · Certolizumab Pegol · Etanercept · Golimumab · Infliximab | 71 | 55 |
| L04AA | Abatacept · Alefacept · Antilymphocyte Immunoglobulin (Horse) · Antithymocyte Immunoglobulin (Rabbit) · Apremilast · +4 more | 73 | 42 |
| L04AK | Leflunomide · Teriflunomide | 44 | 25 |
| L04AH | Everolimus · Sirolimus | 36 | 23 |
| L04AF | Baricitinib · Deucravacitinib · Ritlecitinib · Tofacitinib · Upadacitinib | 23 | 19 |
| L04AG | Alemtuzumab · Anifrolumab · Belimumab · Efalizumab · Inebilizumab · +7 more | 20 | 15 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is SANDOZ CYCLOSPORINE called?
The same molecule, Ciclosporin, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| APO-Ciclosporin | Latin | Australia |
| CICLOSPORIN-WGR | Latin | Australia |
| Sandimmun | Latin | Australia, South Africa |
| Atopica vet. | Latin | Iceland |
| Ikervis | Latin | Australia, Czechia, Iceland |
| Neoral | Latin | Australia |
| SANDIMMUN NEORAL | Latin | Bahrain |
| VERKAZIA | Latin | Bahrain, Saudi Arabia |
| Sporimune vet. | Latin | Iceland |
| Cequa | Latin | Australia |
| Ciclohexal Oral Solution | Latin | South Africa |
| CLASGEN | Latin | Saudi Arabia |
| Optimmune vet. | Latin | Iceland |
| Restasis | Latin | Iceland |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.