DILTIAZEM-CD 180 MG
DILTIAZEM HYDROCHLORIDE : 180 MG · DIN 02231474 · PRO DOC LIMITEE
Health Canada status: CANCELLED POST MARKET
What is DILTIAZEM-CD?
DILTIAZEM-CD 180 MG contains DILTIAZEM HYDROCHLORIDE : 180 MG. It is listed in the Health Canada Drug Product Database under DIN 02231474, held by PRO DOC LIMITEE, supplied as CAPSULE (EXTENDED RELEASE) for ORAL administration. Health Canada currently lists it as cancelled post market, status dated 27-Jul-2021. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is DILTIAZEM-CD used for?
Treatment of mild to moderate hypertension and chronic stable angina (effort-associated angina).
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
What else is DILTIAZEM-CD called?
The same molecule, DILTIAZEM, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| Diltiazem Sandoz CD | Latin | Australia |
| Vasocardol CD | Latin | Australia |
| ADIZEM | Latin | Morocco |
| PROGOR | Latin | Morocco |
| BI-TILDIEM LP | Latin | Morocco |
| Cardizem CD | Latin | Australia |
| MONO-TILDIEM LP | Latin | Morocco |
| Cardizem | Latin | Australia |
| TILDIEM | Latin | Morocco |
| Vasocardol | Latin | Australia |
| ALTIAZEM | Latin | Morocco |
| CRONODINE LP | Latin | Morocco |
| Dilatam | Latin | South Africa |
| DILRENE LP | Latin | Morocco |
| RETALZEM | Latin | Morocco |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
Product details and regulatory record
| DIN | 02231474 |
|---|---|
| Brand name | DILTIAZEM-CD |
| Generic / active ingredient | DILTIAZEM HYDROCHLORIDE : 180 MG |
| Manufacturer | PRO DOC LIMITEE |
| Strength | 180 MG |
| Dosage form | CAPSULE (EXTENDED RELEASE) |
| Route of administration | ORAL |
| Schedule | Prescription |
| ATC code | C08DB01 DILTIAZEM |
| AHFS class | 24:28.92 |
| Biosimilar | No |
| Health Canada status | CANCELLED POST MARKET |
| Status date | 27-Jul-2021 |
| Original market date | 1998-06-02 00:00:00 |
How is this product identified?
Purchase orders, customs paperwork and tender documents each ask for a different identifier, and a DIN written without its leading zeros is the single most common reason an order line fails to match. Every form Nexara accepts for this product is listed here.
| DIN (8-digit, as used in Nexara ordering) | 02231474 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2231474 |
| Brand name | DILTIAZEM-CD |
| Active ingredient / INN | DILTIAZEM HYDROCHLORIDE : 180 MG |
| ATC code | C08DB01 |
| ATC anatomical main group | C — Cardiovascular system |
| ATC therapeutic subgroup | C08 |
| AHFS class | 24:28.92 |
| Health Canada schedule | Prescription |
| Biosimilar biologic | No |
| Market authorization holder | PRO DOC LIMITEE |
How is it administered?
Recommended starting dose is 20 mg or 30 mg once daily. Maximum daily dose is 90 mg. Swallow whole; do not crush or chew.
Included because it drives pack selection and wastage. Consult the monograph.
How is it stored and handled?
Store between 15°C and 30°C. Protect from light and moisture.
How is it supplied?
Available in blister packs and bottles of 100 tablets.
Which pack is which?
| Strength on the label | 180 MG |
|---|---|
| Dosage form | CAPSULE (EXTENDED RELEASE) |
| Route | ORAL |
| Packaging as described in the monograph | Available in blister packs and bottles of 100 tablets. |
| Storage | Store between 15°C and 30°C. Protect from light and moisture. |
One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced. Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation, because this listing covers more than one of them.
Contraindications
Hypersensitivity to nifedipine; pregnancy, breastfeeding; cardiovascular shock; combination with rifampicin.
Warnings and precautions
Caution in patients with hypotension, heart failure, or severe aortic stenosis. May cause increased angina or MI upon initiation or titration.
Is DILTIAZEM in shortage in Canada?
A Canadian shortage report is on file for a product containing this molecule: Active — reported by OMEGA LABORATORIES LIMITED, last seen 04 Sep 2026. A shortage on one presentation does not always affect every DIN of the molecule — the alternatives below list what else is marketed in Canada. Nexara can confirm current availability and identify substitutions or import options where permitted.
What can be used instead?
Other Canadian products sharing ATC code C08DB01 DILTIAZEM. 75 of 175 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.
| Product | Strength | Form | Manufacturer | Health Canada status | DIN |
|---|---|---|---|---|---|
| AA-DILTIAZ | 30 MG | TABLET | AA PHARMA INC | MARKETED | DIN 00771376 |
| AA-DILTIAZ | 60 MG | TABLET | AA PHARMA INC | MARKETED | DIN 00771384 |
| APO-DILTIAZ CD | 120 MG | CAPSULE (CONTROLLED-DELIVERY) | APOTEX INC | MARKETED | DIN 02230997 |
| APO-DILTIAZ CD | 180 MG | CAPSULE (CONTROLLED-DELIVERY) | APOTEX INC | MARKETED | DIN 02230998 |
| APO-DILTIAZ CD | 240 MG | CAPSULE (CONTROLLED-DELIVERY) | APOTEX INC | MARKETED | DIN 02230999 |
| APO-DILTIAZ CD | 300 MG | CAPSULE (CONTROLLED-DELIVERY) | APOTEX INC | MARKETED | DIN 02229526 |
| DILTIAZEM CD | 120 MG | CAPSULE (EXTENDED RELEASE) | SIVEM PHARMACEUTICALS ULC | MARKETED | DIN 02445999 |
| DILTIAZEM CD | 120 MG | CAPSULE (CONTROLLED-DELIVERY) | SANIS HEALTH INC | MARKETED | DIN 02400421 |
| DILTIAZEM CD | 180 MG | CAPSULE (CONTROLLED-DELIVERY) | SANIS HEALTH INC | MARKETED | DIN 02400448 |
| DILTIAZEM CD | 180 MG | CAPSULE (EXTENDED RELEASE) | SIVEM PHARMACEUTICALS ULC | MARKETED | DIN 02446006 |
Who else supplies DILTIAZEM worldwide?
Nexara tracks national medicine registries and published price lists across multiple markets. DILTIAZEM appears in 811 registered pack listings across 11 markets, published on 9 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.
Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.
How much does DILTIAZEM cost around the world?
DILTIAZEM is listed on 9 national price registers Nexara tracks, across 228 pack listings published on 9 different price bases. What each country publishes is set out below.
| Market | What that country publishes | Brands listed | Pack listings | As of |
|---|---|---|---|---|
| United States | acquisition | 21 | 135 | 03 Sep 2026 |
| Morocco | PPV (public price) | 12 | 27 | 05 Sep 2026 |
| Italy | prezzo al pubblico (classe A) | 21 | 24 | 02 Sep 2026 |
| Australia | ex-manufacturer | 5 | 20 | 08 Sep 2026 |
| Greece | producer price (ex-factory) | 10 | 10 | 03 Sep 2026 |
| Romania | max producer price | 5 | 6 | 03 Sep 2026 |
| South Africa | single exit price | 2 | 3 | 01 Sep 2026 |
| Slovakia | categorised final price | 2 | 2 | 02 Sep 2026 |
| United Kingdom | hospital | 1 | 1 | 31 Aug 2026 |
Why there are no figures here. These bases are not comparable. A Brazilian ex-factory ceiling, a Belgian pharmacy public price and a Japanese reimbursement rate answer three different questions, and none of them is what a product lands in Canada for. Putting them side by side would mislead in both directions, so Nexara publishes where a molecule is listed and on what basis, and quotes the delivered Canadian price per order.
Can this still be bought in Canada?
No. This Drug Identification Number is cancelled post market in Health Canada's Drug Product Database, so the product is no longer authorized for sale in Canada and Nexara does not supply it. This page is kept as a regulatory record.
If you are looking for a current equivalent, the alternatives above list every product sharing this therapeutic class, with the marketed ones first. Ask us to source an alternative
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.