PMS-METOPROLOL-L 100 MG — DIN 02230804
METOPROLOL TARTRATE : 100 MG · PHARMASCIENCE INC · TABLET · wholesale supply in Canada
Health Canada status: MARKETED
What is PMS-METOPROLOL-L?
PMS-METOPROLOL-L 100 MG contains METOPROLOL TARTRATE : 100 MG. It is listed in the Health Canada Drug Product Database under DIN 02230804, held by PHARMASCIENCE INC, supplied as TABLET for ORAL administration. Health Canada currently lists it as marketed, status dated 16-Apr-1998. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is PMS-METOPROLOL-L used for?
pms-METOPROLOL-L (metoprolol tartrate) is indicated for mild or moderate hypertension, for the long-term treatment of angina pectoris due to ischemic heart disease, and in the treatment of hemodynamically stable patients with definite or suspected acute myocardial infarction, to reduce cardiovascular mortality.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How much does Metoprolol cost around the world?
Metoprolol is listed on 10 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Belgium publishes a public; Greece publishes a producer price (ex-factory); Hungary publishes a producer price (ex-factory). Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| United States | acquisition | 6 | 79 | USD███.██ |
| Sweden | AIP (pharmacy purchase price) | 6 | 48 | SEK███.██ |
| Romania | max producer price | 28 | 36 | RON███.██ |
| Slovakia | categorised final price | 13 | 13 | EUR███.██ |
| Greece | producer price (ex-factory) | 10 | 10 | EUR███.██ |
| Hungary | producer price (ex-factory) | 10 | 10 | HUF███.██ |
| United Kingdom | hospital | 3 | 3 | GBP███.██ |
| Belgium | public | 2 | 2 | EUR███.██ |
| Morocco | PPV (public price) | 1 | 1 | MAD███.██ |
| South Africa | single exit price | 1 | 1 | ZAR███.██ |
203 pack listings across 80 brand entries and 9 price bases, refreshed 05 Sep 2026. Ranges span every Metoprolol pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Metoprolol in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
28 holders have a Canadian DIN containing Metoprolol, across 103 DINs, of which 30 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| TEVA CANADA LIMITED | 9 | 5 | NTP-METOPROLOL, TEVA-METOPROLOL | Sourceable in Canada |
| APOTEX INC | 5 | 5 | APO-METOPROLOL, APO-METOPROLOL (TYPE L) | Sourceable in Canada |
| PRO DOC LIMITEE | 8 | 3 | METOPROLOL SR, PRO-METOPROLOL, PRO-METOPROLOL-L | Sourceable in Canada |
| PHARMASCIENCE INC | 7 | 3 | PMS-METOPROLOL-B TABLETS - 100MG, PMS-METOPROLOL-B TABLETS - 50MG, PMS-METOPROLOL-L, PMS-METOPROLOL-L SR | Sourceable in Canada |
| JAMP PHARMA CORPORATION | 3 | 3 | JAMP-METOPROLOL-L | Sourceable in Canada |
| LABORATOIRE RIVA INC. | 3 | 3 | RIVA-METOPROLOL-L | Sourceable in Canada |
| SIVEM PHARMACEUTICALS ULC | 3 | 3 | METOPROLOL-L | Sourceable in Canada |
| SANIS HEALTH INC | 2 | 2 | METOPROLOL | Sourceable in Canada |
| SANDOZ CANADA INCORPORATED | 7 | 1 | METOPROLOL TARTRATE INJECTION USP, SANDOZ METOPROLOL (TYPE L), SANDOZ METOPROLOL SR | Sourceable in Canada |
| AA PHARMA INC | 2 | 1 | AA-METOPROLOL SR | Sourceable in Canada |
| JUNO PHARMACEUTICALS CORP. | 1 | 1 | METOPROLOL TARTRATE INJECTION USP | Sourceable in Canada |
| NU-PHARM INC | 9 | 0 | NU-METOP TAB 100MG, NU-METOP TAB 50MG, NU-METOPROLOL, NU-METOPROLOL (TYPE L), NU-METOPROLOL SR | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 100 MG |
|---|---|
| Dosage form | TABLET |
| Route | ORAL |
| Pack configuration (monograph) | null |
| Storage | null |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Metoprolol |
|---|---|
| ATC code | C07AB02 |
| AHFS class | 24:24.00 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02230804 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2230804 |
| Brand name | PMS-METOPROLOL-L |
| Generic / active ingredient | METOPROLOL TARTRATE : 100 MG |
| Market authorization holder | PHARMASCIENCE INC |
| Health Canada schedule | Prescription |
| ATC code | C07AB02 |
| ATC anatomical main group | C — Cardiovascular system |
| ATC therapeutic subgroup | C07AB |
| Current status | MARKETED |
| Status date | 16-Apr-1998 |
| Original market date | 1998-04-16 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
How is it administered?
Hypertension: 100-200mg daily. Angina: 100-400mg daily in divided doses. Myocardial Infarction: Maintenance 100mg twice daily. Administer with or immediately following meals.
Included because it drives pack selection and wastage. Consult the monograph.
Contraindications
Hypersensitivity to metoprolol; sinus bradycardia; sick sinus syndrome; 2nd/3rd degree A-V block; right ventricular failure; overt heart failure; cardiogenic shock; severe peripheral arterial disorders.
Warnings and precautions
Avoid abrupt withdrawal. May mask hypoglycemia in diabetics or symptoms of thyrotoxicosis. Use caution in patients with heart failure, bronchospastic diseases, or peripheral vascular disease.
Is Metoprolol in shortage in Canada?
A Canadian shortage report is on file for a product containing this molecule: Anticipated — reported by SANIS HEALTH INC, last seen 09 Sep 2026. A shortage on one presentation does not always affect every DIN of the molecule — the alternatives below list what else is marketed in Canada. Nexara can confirm current availability and identify substitutions or import options where permitted.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
30 of 103 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| AA-METOPROLOL SR | 100 MG | TABLET (EXTENDED-RELEASE) | AA PHARMA INC | MARKETED | 02285169 |
| APO-METOPROLOL | 50 MG | TABLET | APOTEX INC | MARKETED | 00618632 |
| APO-METOPROLOL | 25 MG | TABLET | APOTEX INC | MARKETED | 02246010 |
| APO-METOPROLOL | 100 MG | TABLET | APOTEX INC | MARKETED | 00618640 |
| APO-METOPROLOL (TYPE L) | 50 MG | TABLET | APOTEX INC | MARKETED | 00749354 |
| APO-METOPROLOL (TYPE L) | 100 MG | TABLET | APOTEX INC | MARKETED | 00751170 |
| JAMP-METOPROLOL-L | 100 MG | TABLET | JAMP PHARMA CORPORATION | MARKETED | 02356848 |
| JAMP-METOPROLOL-L | 25 MG | TABLET | JAMP PHARMA CORPORATION | MARKETED | 02356813 |
| JAMP-METOPROLOL-L | 50 MG | TABLET | JAMP PHARMA CORPORATION | MARKETED | 02356821 |
| METOPROLOL | 100 MG | TABLET | SANIS HEALTH INC | MARKETED | 02350408 |
2 · Same class — other molecules in ATC C07AB
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Metoprolol | AA-METOPROLOL SR · AG-METOPROLOL-L · APO-METOPROLOL · APO-METOPROLOL (TYPE L) · +44 more | 103 | 30 | Yes |
| Atenolol | ACT ATENOLOL · AG-ATENOLOL · APO-ATENOL TAB 100MG · APO-ATENOL TAB 50MG · +35 more | 87 | 28 | Yes |
| Bisoprolol | AG-BISOPROLOL · APO-BISOPROLOL · AVA-BISOPROLOL · BISOPROLOL · +19 more | 52 | 24 | Yes |
| Nebivolol | APO-NEBIVOLOL · BYSTOLIC · JAMP NEBIVOLOL · PRZ-NEBIVOLOL | 13 | 9 | Yes |
| Acebutolol | ACEBUTOLOL · ACEBUTOLOL - 400 · ACEBUTOLOL-100 · ACEBUTOLOL-200 · +20 more | 44 | 6 | Yes |
| Esmolol | BREVIBLOC INJECTION 10MG/ML · BREVIBLOC INJECTION 250MG/ML · BREVIBLOC LIQ IV 10MG/ML · BREVIBLOC LIQ IV 250MG/ML · +1 more | 5 | 2 | Yes |
| Landiolol | SIBBORAN | 1 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC C07A
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| C07AG | Carvedilol · Labetalol | 99 | 38 |
| C07AA | Nadolol · Oxprenolol · Pindolol · Propranolol · Sotalol · +1 more | 177 | 27 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is PMS-METOPROLOL-L called?
The same molecule, Metoprolol, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| Metoprolol Sandoz | Latin | Sweden |
| SelokenZOC® | Latin | Sweden |
| Bloxazoc | Latin | Sweden |
| Metoprolol Teva | Latin | Sweden |
| Metoprolol Orion | Latin | Sweden |
| Metomylan | Latin | Sweden |
| Lopresor | Latin | South Africa |
| LOPRESSOR RETARD | Latin | Morocco |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.