CELL TECH ENZYMES - CAP 375 UNIT — DIN 02216442
LACTASE : 375 UNIT CELLULASE : 10 UNIT AMYLASE : 1000 UNIT LIPASE : 750 UNIT PROTEASE : 4000 UNIT · CELL TECH · CAPSULE · wholesale supply in Canada
Health Canada status: CANCELLED POST MARKET
What is CELL TECH ENZYMES - CAP?
CELL TECH ENZYMES - CAP 375 UNIT contains LACTASE : 375 UNIT CELLULASE : 10 UNIT AMYLASE : 1000 UNIT LIPASE : 750 UNIT PROTEASE : 4000 UNIT. It is listed in the Health Canada Drug Product Database under DIN 02216442, held by CELL TECH, supplied as CAPSULE for ORAL administration. Health Canada currently lists it as cancelled post market, status dated 05-Oct-2000. This Drug Identification Number is no longer authorized for sale in Canada, so Nexara does not supply it. The record is kept here because buyers still meet the number on old formularies, purchase orders and tender documents; Nexara can help identify an authorized alternative.
Is there a generic Multienzymes (Lipase, Protease Etc) in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
36 holders have a Canadian DIN containing Multienzymes (Lipase, Protease Etc), across 65 DINs, of which 14 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| VIVUS LLC. | 5 | 5 | PANCREASE MT 10, PANCREASE MT 16, PANCREASE MT 2, PANCREASE MT 20, PANCREASE MT 4 | Sourceable in Canada |
| BGP PHARMA ULC | 6 | 4 | CREON MINIMICROSPHERES 10, CREON MINIMICROSPHERES 20, CREON MINIMICROSPHERES 25, CREON MINIMICROSPHERES 35, CREON MINIMICROSPHERES 6, +1 more | Sourceable in Canada |
| ORGANON CANADA INC. | 3 | 3 | COTAZYM, COTAZYM ECS 20, COTAZYM ECS 8 | Sourceable in Canada |
| NESTLE ENTERPRISES S.A. | 2 | 2 | VIOKACE | Sourceable in Canada |
| PAINES AND BYRNE LTD. | 5 | 0 | PANCREX GRANULES, PANCREX V CAPSULES, PANCREX V FORTE TABLETS 1GM/TAB, PANCREX V POWDER, PANCREX V TAB 0.33GM | No marketed DIN |
| APTALIS PHARMA CANADA ULC | 4 | 0 | ULTRASE, ULTRESA | No marketed DIN |
| NU-LIFE NUTRITION LTD. | 3 | 0 | BROMELAIN 500 + PAPAIN AND GALACTOSIDASE, PAPAYA ZYME TAB NU LIFE, VEGE-DIGEST DIGESTIVE AID | No marketed DIN |
| AXCAN PHARMA INC | 2 | 0 | DIGESS 8000 - CAP, VIOKASE POWDER | No marketed DIN |
| AYERST LABORATORIES | 2 | 0 | VIOKASE PWR, VIOKASE TAB | No marketed DIN |
| GAHLER ENTERPRISES LTD. | 2 | 0 | CHEWABLE ENZYMES TABLETS, PANCREATINE ENZYMES | No marketed DIN |
| JAMIESON LABORATORIES LTD | 2 | 0 | PANCREATIN TAB 400MG, SUPER PAYA JAY TAB | No marketed DIN |
| METAGENICS, INC. | 2 | 0 | BIO-ZYME TAB 50MG, METAZYME CAP | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 375 UNIT |
|---|---|
| Dosage form | CAPSULE |
| Route | ORAL |
Pack detail is kept as a regulatory record. This DIN is no longer authorized for sale in Canada, so Nexara does not quote this pack.
Substance and classification
| Active substance | Multienzymes (Lipase, Protease Etc) |
|---|---|
| ATC code | A09AA02 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02216442 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2216442 |
| Brand name | CELL TECH ENZYMES - CAP |
| Generic / active ingredient | LACTASE : 375 UNIT CELLULASE : 10 UNIT AMYLASE : 1000 UNIT LIPASE : 750 UNIT PROTEASE : 4000 UNIT |
| Market authorization holder | CELL TECH |
| Health Canada schedule | NON-PRESCRIPTION DRUGS |
| ATC code | A09AA02 |
| ATC anatomical main group | A — Alimentary tract and metabolism |
| ATC therapeutic subgroup | A09AA |
| Current status | CANCELLED POST MARKET |
| Status date | 05-Oct-2000 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
14 of 65 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| COTAZYM | 35000 UNIT | CAPSULE (IMMEDIATE RELEASE) | ORGANON CANADA INC. | MARKETED | 00263818 |
| COTAZYM ECS 20 | 25000 UNIT | CAPSULE (DELAYED RELEASE) | ORGANON CANADA INC. | MARKETED | 00821373 |
| COTAZYM ECS 8 | 10800 UNIT | CAPSULE (DELAYED RELEASE) | ORGANON CANADA INC. | MARKETED | 00502790 |
| CREON MINIMICROSPHERES 10 | 10000 UNIT | CAPSULE (DELAYED RELEASE) | BGP PHARMA ULC | MARKETED | 02200104 |
| CREON MINIMICROSPHERES 25 | 25000 UNIT | CAPSULE (DELAYED RELEASE) | BGP PHARMA ULC | MARKETED | 01985205 |
| CREON MINIMICROSPHERES 35 | 35700 UNIT | CAPSULE (DELAYED RELEASE) | BGP PHARMA ULC | MARKETED | 02494639 |
| CREON MINIMICROSPHERES MICRO | 5000 UNIT / 100 MG | GRANULES FOR SUSPENSION, DELAYED RELEASE | BGP PHARMA ULC | MARKETED | 02445158 |
| PANCREASE MT 10 | 43750 UNIT | CAPSULE (DELAYED RELEASE) | VIVUS LLC. | MARKETED | 00789437 |
| PANCREASE MT 16 | 70000 UNIT | CAPSULE (DELAYED RELEASE) | VIVUS LLC. | MARKETED | 00789429 |
| PANCREASE MT 2 | 6200 UNIT | CAPSULE (DELAYED RELEASE) | VIVUS LLC. | MARKETED | 02503433 |
2 · Same class — other molecules in ATC A09AA
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Multienzymes (Lipase, Protease Etc) | BIO-ZYME TAB 50MG · BROMELAIN 500 + PAPAIN AND GALACTOSIDASE · BROMELAIN AND PAPAIN TAB · CELL TECH ENZYMES - CAP · +57 more | 65 | 14 | Yes |
| Tilactase | DAIRY DIGESTIVE AID TAB 3000FCC LACTASE UNIT · DAIRY DIGESTIVE ULTRA STRENGTH SUPPLEMENT · EXTRA STRENGTH LACTAID TABLETS - 4500FCCLU · LACTACE CAP 3400UNIT · +7 more | 11 | 0 | Not in Canada |
| Enzyme Preparations | BEANO DROPS · BEANO DROPS 780UNITS/ML · BEANO TABLETS 150 GALUNITS/TAB · FORMULA C & E · +6 more | 10 | 0 | Not in Canada |
| Pepsin, Combinations | DIGEST EASE · PEPSOTOL | 2 | 0 | Not in Canada |
| Pepsin | DIGESTEX | 1 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC A09A
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| A09AB | Betaine Hydrochloride · Betaine Hydrochloride, Combinations · Glutamic Acid Hydrochloride | 4 | 0 |
| A09AC | Enzyme And Acid Preparations, Combinations · Multienzymes And Acid Preparations · Pepsin And Acid Preparations | 23 | 0 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
Can this still be bought in Canada?
No. This Drug Identification Number is cancelled post market in Health Canada's Drug Product Database, so the product is no longer authorized for sale in Canada and Nexara does not supply it. This page is kept as a regulatory record.
If you are looking for a current equivalent, the alternatives above list every product sharing this therapeutic class, with the marketed ones first. Ask us to source an alternative
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.