IMDUR 60 MG — DIN 02126559
ISOSORBIDE-5-MONONITRATE : 60 MG · JUNO PHARMACEUTICALS CORP. · TABLET (EXTENDED-RELEASE) · wholesale supply in Canada
Health Canada status: DORMANT
What is IMDUR?
IMDUR 60 MG contains ISOSORBIDE-5-MONONITRATE : 60 MG. It is listed in the Health Canada Drug Product Database under DIN 02126559, held by JUNO PHARMACEUTICALS CORP., supplied as TABLET (EXTENDED-RELEASE) for ORAL administration. Health Canada currently lists it as dormant, status dated 29-Jul-2026. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A). This DIN is not currently being marketed in Canada, so it is sourced to order where a compliant route exists rather than held in stock.
What is IMDUR used for?
Prevention of anginal attacks in patients with chronic stable angina pectoris associated with coronary artery disease. Not for immediate relief of acute attacks.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How much does Isosorbide Mononitrate cost around the world?
Isosorbide Mononitrate is listed on 2 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Bahrain publishes a retail (max); Greece publishes a producer price (ex-factory). Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| Greece | producer price (ex-factory) | 5 | 5 | EUR███.██ |
| Bahrain | retail (max) | 1 | 1 | BHD███.██ |
6 pack listings across 6 brand entries and 2 price bases, refreshed 03 Sep 2026. Ranges span every Isosorbide Mononitrate pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Isosorbide Mononitrate in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
8 holders have a Canadian DIN containing Isosorbide Mononitrate, across 8 DINs, of which 3 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| APOTEX INC | 1 | 1 | APO-ISMN | Sourceable in Canada |
| PHARMASCIENCE INC | 1 | 1 | PMS-ISMN | Sourceable in Canada |
| PRO DOC LIMITEE | 1 | 1 | PRO-ISMN - 60 | Sourceable in Canada |
| DOMINION PHARMACAL | 1 | 0 | DOM-ISMN | No marketed DIN |
| JUNO PHARMACEUTICALS CORP. | 1 | 0 | IMDUR | No marketed DIN |
| PHARMEL INC | 1 | 0 | PHL-ISMN | No marketed DIN |
| SIVEM PHARMACEUTICALS ULC | 1 | 0 | ISMN | No marketed DIN |
| WYETH-AYERST CANADA INC. | 1 | 0 | ISMO TAB 20MG | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 60 MG |
|---|---|
| Dosage form | TABLET (EXTENDED-RELEASE) |
| Route | ORAL |
| Pack configuration (monograph) | Compliance blister packs of 30 tablets; bottles of 100 tablets. |
| Storage | Store at 15-30°C. |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation, because this listing covers more than one of them.
Substance and classification
| Active substance | Isosorbide Mononitrate |
|---|---|
| ATC code | C01DA14 |
| AHFS class | 84:04.08.08 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02126559 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2126559 |
| Brand name | IMDUR |
| Generic / active ingredient | ISOSORBIDE-5-MONONITRATE : 60 MG |
| Market authorization holder | JUNO PHARMACEUTICALS CORP. |
| Health Canada schedule | Ethical |
| ATC code | C01DA14 |
| ATC anatomical main group | C — Cardiovascular system |
| ATC therapeutic subgroup | C01DA |
| Current status | DORMANT |
| Status date | 29-Jul-2026 |
| Original market date | 1980-12-31 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
How is it administered?
Starting dose 60 mg once daily in the morning. May increase to 120 mg. Titrate with 30 mg to minimize headache. Swallow whole or as halves; do not chew or crush.
Included because it drives pack selection and wastage. Consult the monograph.
Contraindications
Hypersensitivity to nitrates; acute circulatory failure/shock; postural hypotension; myocardial insufficiency due to obstruction; increased intracranial pressure; severe anemia; use with PDE5 inhibitors.
Warnings and precautions
Not established for acute MI or CHF. Avoid abrupt withdrawal. Caution in severe cerebral arteriosclerosis, severe hypotension, volume depletion, or arterial hypoxemia.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
3 of 8 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| APO-ISMN | 60 MG | TABLET (EXTENDED-RELEASE) | APOTEX INC | MARKETED | 02272830 |
| PMS-ISMN | 60 MG | TABLET (EXTENDED-RELEASE) | PHARMASCIENCE INC | MARKETED | 02301288 |
| PRO-ISMN - 60 | 60 MG | TABLET (EXTENDED-RELEASE) | PRO DOC LIMITEE | MARKETED | 02311321 |
| DOM-ISMN | 60 MG | TABLET (EXTENDED-RELEASE) | DOMINION PHARMACAL | CANCELLED PRE MARKET | 02307758 |
| ISMN | 60 MG | TABLET (EXTENDED-RELEASE) | SIVEM PHARMACEUTICALS ULC | CANCELLED POST MARKET | 02446073 |
| ISMO TAB 20MG | 20 MG | TABLET | WYETH-AYERST CANADA INC. | CANCELLED POST MARKET | 02058472 |
| PHL-ISMN | 60 MG | TABLET (EXTENDED-RELEASE) | PHARMEL INC | CANCELLED PRE MARKET | 02307731 |
2 · Same class — other molecules in ATC C01DA
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Glyceryl Trinitrate | APO-NITROGLYCERIN · MINITRAN · MINITRAN - PATCH TRD 72MG/26.6 SQ CM · MYLAN-NITRO PATCH 0.2 · +31 more | 39 | 18 | Yes |
| Isosorbide Mononitrate | APO-ISMN · DOM-ISMN · IMDUR · ISMN · +4 more | 8 | 3 | Yes |
| Isosorbide Dinitrate | CEDOCARD-SR SRT 20MG · CEDOCARD-SR SRT 40MG · CORADUR TAB 20MG · CORONEX · +16 more | 25 | 2 | Yes |
| Pentaerithrityl Tetranitrate | PERITRATE SA 80MG TAB · PERITRATE TAB 10MG · PERITRATE TAB 20MG | 3 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC C01D
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| C01DX | Nesiritide · Vericiguat | 4 | 3 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is IMDUR called?
The same molecule, Isosorbide Mononitrate, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| ISOBIDE | Latin | Bahrain |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
This DIN is dormant — it holds a Health Canada authorization but is not currently being marketed in Canada, so it cannot simply be ordered from Canadian stock. Where a patient need exists, supply may be possible through exceptional importation or the Special Access Programme, subject to Health Canada's requirements and the prescriber's application. Nexara can advise on the route and on marketed alternatives.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.