DANTRIUM INTRAVENOUS 20 MG — DIN 01997572
DANTROLENE SODIUM : 20 MG · ENDO OPERATIONS LTD. · POWDER FOR SOLUTION · wholesale supply in Canada
Health Canada status: MARKETED
What is DANTRIUM INTRAVENOUS?
DANTRIUM INTRAVENOUS 20 MG contains DANTROLENE SODIUM : 20 MG. It is listed in the Health Canada Drug Product Database under DIN 01997572, held by ENDO OPERATIONS LTD., supplied as POWDER FOR SOLUTION for INTRAVENOUS administration. Health Canada currently lists it as marketed, status dated 16-Jan-2026. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is DANTRIUM INTRAVENOUS used for?
DANTRIUM INTRAVENOUS (dantrolene sodium for injection) is indicated in: • the management of malignant hyperthermia crisis.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How much does Dantrolene cost around the world?
Dantrolene is listed on 4 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Australia publishes a ex-manufacturer; Iceland publishes a max wholesale; South Africa publishes a single exit price. Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| United States | acquisition | 3 | 14 | USD███.██ |
| South Africa | single exit price | 3 | 4 | ZAR███.██ |
| Australia | ex-manufacturer | 1 | 1 | AUD███.██ |
| Iceland | max wholesale | 1 | 1 | ISK███.██ |
20 pack listings across 8 brand entries and 4 price bases, refreshed 08 Sep 2026. Ranges span every Dantrolene pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Dantrolene in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
4 holders have a Canadian DIN containing Dantrolene, across 6 DINs, of which 3 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| ENDO OPERATIONS LTD. | 2 | 2 | DANTRIUM CAPSULES, DANTRIUM INTRAVENOUS | Sourceable in Canada |
| HIKMA CANADA LIMITED | 1 | 1 | DANTROLENE SODIUM FOR INJECTION, USP | Sourceable in Canada |
| NORWICH EATON CANADA INC. | 2 | 0 | DANTRIUM CAP 100MG, DANTRIUM CAP 25MG | No marketed DIN |
| PAR PHARMACEUTICAL COMPANIES | 1 | 0 | DANTRIUM CAPSULES | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 20 MG |
|---|---|
| Dosage form | POWDER FOR SOLUTION |
| Route | INTRAVENOUS |
| Pack configuration (monograph) | cartons of 6 vials |
| Storage | Unreconstituted vials: Store at controlled room temperature (20°C to 25°C) and protected from light. Reconstituted vials: Store reconstituted solution between 15°C to 30°C, protected from light. The reconstituted solution must be used within 6 hours after reconstitution. |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Dantrolene |
|---|---|
| ATC code | M03CA01 |
| AHFS class | 12:20.08 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 01997572 |
|---|---|
| DIN (unpadded, as printed on some documents) | 1997572 |
| Brand name | DANTRIUM INTRAVENOUS |
| Generic / active ingredient | DANTROLENE SODIUM : 20 MG |
| Market authorization holder | ENDO OPERATIONS LTD. |
| Health Canada schedule | Prescription |
| ATC code | M03CA01 |
| ATC anatomical main group | M — Musculo-skeletal system |
| ATC therapeutic subgroup | M03CA |
| Current status | MARKETED |
| Status date | 16-Jan-2026 |
| Original market date | 1993-12-31 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
Is Dantrolene in shortage in Canada?
A Canadian shortage report is on file for a product containing this molecule: Anticipated — reported by HIKMA CANADA LIMITED, last seen 09 Sep 2026. A shortage on one presentation does not always affect every DIN of the molecule — the alternatives below list what else is marketed in Canada. Nexara can confirm current availability and identify substitutions or import options where permitted.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
3 of 6 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| DANTRIUM CAPSULES | 25 MG | CAPSULE | ENDO OPERATIONS LTD. | MARKETED | 01997602 |
| DANTROLENE SODIUM FOR INJECTION, USP | 20 MG | POWDER FOR SOLUTION | HIKMA CANADA LIMITED | MARKETED | 02529998 |
| DANTRIUM CAP 100MG | 100 MG | CAPSULE | NORWICH EATON CANADA INC. | CANCELLED POST MARKET | 00452521 |
| DANTRIUM CAP 25MG | 25 MG | CAPSULE | NORWICH EATON CANADA INC. | CANCELLED POST MARKET | 00452513 |
| DANTRIUM CAPSULES | 100 MG | CAPSULE | PAR PHARMACEUTICAL COMPANIES | CANCELLED POST MARKET | 01997653 |
2 · Same class — other molecules in ATC M03CA
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Dantrolene | DANTRIUM CAP 100MG · DANTRIUM CAP 25MG · DANTRIUM CAPSULES · DANTRIUM INTRAVENOUS · +1 more | 6 | 3 | Yes |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is DANTRIUM INTRAVENOUS called?
The same molecule, Dantrolene, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| Dantrium | Latin | Australia, South Africa |
| Dantrium iv | Latin | South Africa |
| Agilus | Latin | Iceland |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.