MAJEPTIL 10 MG — DIN 01927639
THIOPROPERAZINE (THIOPROPERAZINE MESYLATE) : 10 MG · SEARCHLIGHT PHARMA INC · TABLET · wholesale supply in Canada
Health Canada status: CANCELLED POST MARKET
What is MAJEPTIL?
MAJEPTIL 10 MG contains THIOPROPERAZINE (THIOPROPERAZINE MESYLATE) : 10 MG. It is listed in the Health Canada Drug Product Database under DIN 01927639, held by SEARCHLIGHT PHARMA INC, supplied as TABLET for ORAL administration. Health Canada currently lists it as cancelled post market, status dated 18-Jul-2024. This Drug Identification Number is no longer authorized for sale in Canada, so Nexara does not supply it. The record is kept here because buyers still meet the number on old formularies, purchase orders and tender documents; Nexara can help identify an authorized alternative.
What is MAJEPTIL used for?
All types of acute and chronic schizophrenia, including treatment-resistant cases; manic syndromes.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 10 MG |
|---|---|
| Dosage form | TABLET |
| Route | ORAL |
| Pack configuration (monograph) | Bottles of 100 tablets. |
| Storage | Protect from light. Store between 15 – 30 °C. |
Pack detail is kept as a regulatory record. This DIN is no longer authorized for sale in Canada, so Nexara does not quote this pack.
Substance and classification
| Active substance | Thioproperazine |
|---|---|
| ATC code | N05AB08 |
| AHFS class | 28:16.08.24 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 01927639 |
|---|---|
| DIN (unpadded, as printed on some documents) | 1927639 |
| Brand name | MAJEPTIL |
| Generic / active ingredient | THIOPROPERAZINE (THIOPROPERAZINE MESYLATE) : 10 MG |
| Market authorization holder | SEARCHLIGHT PHARMA INC |
| Health Canada schedule | Prescription |
| ATC code | N05AB08 |
| ATC anatomical main group | N — Nervous system |
| ATC therapeutic subgroup | N05AB |
| Current status | CANCELLED POST MARKET |
| Status date | 18-Jul-2024 |
| Original market date | 1962-12-31 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
How is it administered?
Adults: Start 5 mg/day, increase to 30-40 mg/day. Children >10: Start 1-3 mg/day. Maintenance: lowest effective level. Discontinuous treatment reserved for resistant cases.
Included because it drives pack selection and wastage. Consult the monograph.
Contraindications
Comatose/depressive states; Parkinson's disease; blood dyscrasias; spastic diseases; senile patients with Parkinson-like symptoms; children under 3; sensitivity to phenothiazines.
Warnings and precautions
Increased mortality in elderly with dementia. Risk of Neuroleptic Malignant Syndrome, Tardive Dyskinesia, QT prolongation, and Venous Thromboembolism. May impair driving ability.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
2 · Same class — other molecules in ATC N05AB
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Perphenazine | PERPHENAZINE · PERPHENAZINE 16 TAB · PERPHENAZINE 2 TAB 2MG · PERPHENAZINE 8 TAB 8MG · +17 more | 25 | 4 | Yes |
| Fluphenazine | APO FLUPHENAZINE TAB 2.5MG · APO-FLUPHENAZINE INJECTABLE · FLUPHENAZINE · FLUPHENAZINE 1 TAB 1MG · +17 more | 25 | 3 | Yes |
| Prochlorperazine | NU-PROCHLOR TAB 10MG · NU-PROCHLOR TAB 5MG · ODAN-PROCHLORPERAZINE · PMS PROCHLORPERAZINE INJ 5MG/ML · +9 more | 15 | 3 | Yes |
| Trifluoperazine | NOVO-FLURAZINE TAB 1MG · NOVO-FLURAZINE TAB 20MG · NOVO-TRIFLUZINE - TAB 10MG · NOVO-TRIFLUZINE - TAB 2MG · +26 more | 38 | 0 | Not in Canada |
| Thioproperazine | MAJEPTIL | 1 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC N05A
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| N05AH | Asenapine · Clozapine · Loxapine · Olanzapine · Quetiapine | 589 | 220 |
| N05AX | Aripiprazole · Brexpiprazole · Cariprazine · Paliperidone · Risperidone | 352 | 175 |
| N05AE | Lurasidone · Ziprasidone | 60 | 41 |
| N05AD | Droperidol · Haloperidol | 53 | 9 |
| N05AF | Flupentixol · Tiotixene · Zuclopenthixol | 25 | 8 |
| N05AA | Chlorpromazine · Levomepromazine · Promazine | 51 | 8 |
| N05AN | Lithium | 26 | 7 |
| N05AC | Mesoridazine · Periciazine · Pipotiazine · Thioridazine | 32 | 3 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
Can this still be bought in Canada?
No. This Drug Identification Number is cancelled post market in Health Canada's Drug Product Database, so the product is no longer authorized for sale in Canada and Nexara does not supply it. This page is kept as a regulatory record.
If you are looking for a current equivalent, the alternatives above list every product sharing this therapeutic class, with the marketed ones first. Ask us to source an alternative
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.