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FLAGYSTATIN 500 MG

METRONIDAZOLE : 500 MG NYSTATIN : 100000 UNIT · DIN 01926837 · AVENTIS PHARMA INC

Health Canada status: CANCELLED POST MARKET

What is FLAGYSTATIN?

FLAGYSTATIN 500 MG contains METRONIDAZOLE : 500 MG NYSTATIN : 100000 UNIT. It is listed in the Health Canada Drug Product Database under DIN 01926837, held by AVENTIS PHARMA INC, supplied as SUPPOSITORY for VAGINAL administration. Health Canada currently lists it as cancelled post market, status dated 30-Jul-2004. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.

What is FLAGYSTATIN used for?

Mixed vaginal infection due to Trichomonas vaginalis and Candida albicans.

Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.

Product details and regulatory record

DIN01926837
Brand nameFLAGYSTATIN
Generic / active ingredientMETRONIDAZOLE : 500 MG NYSTATIN : 100000 UNIT
ManufacturerAVENTIS PHARMA INC
Strength500 MG
Dosage formSUPPOSITORY
Route of administrationVAGINAL
SchedulePrescription
ATC codeG01AA51 NYSTATIN, COMBINATIONS
AHFS class84:04.08.28 ; 84:04.92
BiosimilarNo
Health Canada statusCANCELLED POST MARKET
Status date30-Jul-2004
Original market date1972-12-31 00:00:00

How is it administered?

One vaginal ovule daily, inserted deep into the vagina, for 10 consecutive days. A second 10-day course may be given if cure is not achieved.

Included because it drives pack selection and wastage. Consult the monograph.

How is it stored and handled?

Store at room temperature between 15 - 25ºC and protect from light.

How is it supplied?

Boxes of 10 ovules with applicator.

Contraindications

Hypersensitivity to metronidazole, nystatin, or imidazoles. Combined oral metronidazole avoided in active neurological disorders, blood dyscrasia, hypothyroidism, or hypoadrenalism.

Warnings and precautions

Metronidazole is carcinogenic in rodents. Risk of severe hepatotoxicity in Cockayne syndrome. Potential for peripheral/central neuropathy. May impair condoms/diaphragms.

What can be used instead?

Other Canadian products sharing ATC code G01AA51 NYSTATIN, COMBINATIONS. 1 of 3 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.

ProductStrengthFormManufacturerHealth Canada statusDIN
FLAGYSTATIN100000 UNITOVULESANOFI-AVENTIS CANADA INCMARKETEDDIN 01926829
FLAGYSTATIN100000 UNIT / 4.5 GCREAMSANOFI-AVENTIS CANADA INCCANCELLED POST MARKETDIN 01926845

How can I get it?

Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.

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Ordering questions

Who can buy this from Nexara?

Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.

Is there a minimum order?

Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.

What is the lead time?

Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.

Can Nexara supply this for a clinical trial?

Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.

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Health Canada Drug Product Database (DPD), DIN 01926837. Last reviewed 2026-09-08. Nexara Health is a licensed wholesaler and supplies licensed entities only; consumer orders are routed to a partner pharmacy.