APO-PROPRANOLOL 20 MG — DIN 00663719
PROPRANOLOL HYDROCHLORIDE : 20 MG · APOTEX INC · TABLET · wholesale supply in Canada
Health Canada status: DORMANT
What is APO-PROPRANOLOL?
APO-PROPRANOLOL 20 MG contains PROPRANOLOL HYDROCHLORIDE : 20 MG. It is listed in the Health Canada Drug Product Database under DIN 00663719, held by APOTEX INC, supplied as TABLET for ORAL administration. Health Canada currently lists it as dormant, status dated 29-Jan-2021. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A). This DIN is not currently being marketed in Canada, so it is sourced to order where a compliant route exists rather than held in stock.
What is APO-PROPRANOLOL used for?
APO-PROPRANOLOL is indicated in the treatment of mild to moderate hypertension and for the prophylaxis of angina pectoris. APO-PROPRANOLOL is also indicated for the treatment of cardiac arrhythmias, migraine headache prophylaxis, hypertrophic subaortic stenosis, and as adjunctive therapy for pheochromocytoma.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How much does Propranolol cost around the world?
Propranolol is listed on 13 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Australia publishes a ex-manufacturer; Greece publishes a producer price (ex-factory); Hungary publishes a producer price (ex-factory). Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| United States | acquisition | 7 | 91 | USD███.██ |
| Australia | ex-manufacturer | 5 | 16 | AUD███.██ |
| Sweden | AIP (pharmacy purchase price) | 5 | 16 | SEK███.██ |
| South Africa | single exit price | 9 | 11 | ZAR███.██ |
| United Kingdom | hospital | 9 | 9 | GBP███.██ |
| Romania | max producer price | 6 | 9 | RON███.██ |
| Saudi Arabia | public | 6 | 8 | SAR███.██ |
| Morocco | PPV (public price) | 3 | 4 | MAD███.██ |
| United Arab Emirates | public | 3 | 3 | AED███.██ |
| Spain | PVP con IVA (public price) | 3 | 3 | EUR███.██ |
| Hungary | producer price (ex-factory) | 3 | 3 | HUF███.██ |
| Greece | producer price (ex-factory) | 2 | 2 | EUR███.██ |
| Slovakia | categorised final price | 1 | 1 | EUR███.██ |
176 pack listings across 62 brand entries and 11 price bases, refreshed 08 Sep 2026. Ranges span every Propranolol pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Propranolol in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
16 holders have a Canadian DIN containing Propranolol, across 56 DINs, of which 13 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| LUPIN PHARMA CANADA LIMITED | 4 | 4 | LUPIN-PROPRANOLOL LA | Sourceable in Canada |
| TEVA CANADA LIMITED | 4 | 4 | TEVA-PROPRANOLOL | Sourceable in Canada |
| PHARMARIS CANADA INC | 3 | 3 | PRZ-PROPRANOLOL | Sourceable in Canada |
| PIERRE FABRE DERMO-COSMETIQUE CANADA INC | 1 | 1 | HEMANGIOL | Sourceable in Canada |
| SANDOZ CANADA INCORPORATED | 1 | 1 | PROPRANOLOL HYDROCHLORIDE INJECTION USP | Sourceable in Canada |
| WYETH-AYERST CANADA INC. | 6 | 0 | INDERAL INJECTABLE LIQ 1MG/ML, INDERAL-10 TAB 10MG, INDERAL-120 TAB 120MG, INDERAL-20 TAB 20MG, INDERAL-40 TAB 40MG, +1 more | No marketed DIN |
| APOTEX INC | 5 | 0 | APO-PROPRANOLOL | No marketed DIN |
| AYERST LABORATORIES | 5 | 0 | INDERAL 20 TAB 20MG, INDERAL 80 TAB, INDERAL LA CAP 160MG, INDERAL LA CAP 80MG, INDERAL TAB 120MG | No marketed DIN |
| NU-PHARM INC | 5 | 0 | NU-PROPRANOLOL TAB 10MG, NU-PROPRANOLOL TAB 120MG, NU-PROPRANOLOL TAB 20MG, NU-PROPRANOLOL TAB 40MG, NU-PROPRANOLOL TAB 80MG | No marketed DIN |
| PRO DOC LIMITEE | 5 | 0 | PROPRANOLOL TAB 10MG, PROPRANOLOL TAB 40MG, PROPRANOLOL TAB 80MG, PROPRANOLOL-120 TAB 120MG, PROPRANOLOL-20 TAB 20MG | No marketed DIN |
| DESBERGERS LTÉE, DIVISION OF TECHNILAB INC. | 4 | 0 | DETENSOL TAB 10MG, DETENSOL TAB 120MG, DETENSOL TAB 40MG, DETENSOL TAB 80MG | No marketed DIN |
| PHARMASCIENCE INC | 4 | 0 | PMS-PROPRANOLOL TABLETS 10MG, PMS-PROPRANOLOL TABLETS 120MG, PMS-PROPRANOLOL TABLETS 40MG, PMS-PROPRANOLOL TABLETS 80MG | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 20 MG |
|---|---|
| Dosage form | TABLET |
| Route | ORAL |
| Pack configuration (monograph) | null |
| Storage | null |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Propranolol |
|---|---|
| ATC code | C07AA05 |
| AHFS class | 24:24.00 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 00663719 |
|---|---|
| DIN (unpadded, as printed on some documents) | 663719 |
| Brand name | APO-PROPRANOLOL |
| Generic / active ingredient | PROPRANOLOL HYDROCHLORIDE : 20 MG |
| Market authorization holder | APOTEX INC |
| Health Canada schedule | Prescription |
| ATC code | C07AA05 |
| ATC anatomical main group | C — Cardiovascular system |
| ATC therapeutic subgroup | C07AA |
| Current status | DORMANT |
| Status date | 29-Jan-2021 |
| Original market date | 1986-12-31 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
How is it administered?
Dosage must be individualized. For angina/hypertension, usually started at low doses. Abrupt cessation should be avoided; taper over 2 weeks. Not for emergency hypertensive crisis.
Included because it drives pack selection and wastage. Consult the monograph.
Contraindications
Bronchospasm, asthma, allergic rhinitis, sinus bradycardia, >1st degree block, cardiogenic shock, heart failure, hypotension, metabolic acidosis, severe peripheral arterial disease, Prinzmetal's angina.
Warnings and precautions
Cardiac failure risk; avoid abrupt cessation in angina (risk of MI); masks hypoglycemia/thyrotoxicosis signs; caution in surgery/anesthesia; risk of bronchospasm in susceptible patients.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
13 of 56 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| HEMANGIOL | 3.75 MG | SOLUTION | PIERRE FABRE DERMO-COSMETIQUE CANADA INC | MARKETED | 02457857 |
| LUPIN-PROPRANOLOL LA | 120 MG | CAPSULE (EXTENDED RELEASE) | LUPIN PHARMA CANADA LIMITED | MARKETED | 02491915 |
| LUPIN-PROPRANOLOL LA | 160 MG | CAPSULE (EXTENDED RELEASE) | LUPIN PHARMA CANADA LIMITED | MARKETED | 02491923 |
| LUPIN-PROPRANOLOL LA | 60 MG | CAPSULE (EXTENDED RELEASE) | LUPIN PHARMA CANADA LIMITED | MARKETED | 02491893 |
| LUPIN-PROPRANOLOL LA | 80 MG | CAPSULE (EXTENDED RELEASE) | LUPIN PHARMA CANADA LIMITED | MARKETED | 02491907 |
| PROPRANOLOL HYDROCHLORIDE INJECTION USP | 1 MG | SOLUTION | SANDOZ CANADA INCORPORATED | MARKETED | 02225883 |
| PRZ-PROPRANOLOL | 40 MG | TABLET | PHARMARIS CANADA INC | MARKETED | 02550822 |
| PRZ-PROPRANOLOL | 80 MG | TABLET | PHARMARIS CANADA INC | MARKETED | 02550830 |
| PRZ-PROPRANOLOL | 20 MG | TABLET | PHARMARIS CANADA INC | MARKETED | 02550814 |
| TEVA-PROPRANOLOL | 10 MG | TABLET | TEVA CANADA LIMITED | MARKETED | 00496480 |
2 · Same class — other molecules in ATC C07AA
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Propranolol | APO-PROPRANOLOL · DETENSOL TAB 10MG · DETENSOL TAB 120MG · DETENSOL TAB 40MG · +36 more | 56 | 13 | Yes |
| Nadolol | APO-NADOLOL · CORGARD TAB 160MG · CORGARD TAB 40MG · CORGARD TAB 80MG · +8 more | 16 | 5 | Yes |
| Sotalol | APO-SOTALOL · AVA-SOTALOL · CO SOTALOL · DOM-SOTALOL · +27 more | 55 | 3 | Yes |
| Pindolol | APO-PINDOL TAB 10MG · APO-PINDOL TAB 15MG · APO-PINDOL TAB 5MG · DOM-PINDOLOL · +15 more | 30 | 3 | Yes |
| Timolol | BLOCADREN TAB 10MG · BLOCADREN TAB 20MG · BLOCADREN TAB 5MG · NU-TIMOLOL TAB 10MG · +7 more | 15 | 3 | Yes |
| Oxprenolol | SLOW TRASICOR TAB 160MG · SLOW TRASICOR TAB 80MG · TRASICOR TAB 20MG · TRASICOR TAB 40MG · +1 more | 5 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC C07A
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| C07AB | Acebutolol · Atenolol · Bisoprolol · Esmolol · Landiolol · +2 more | 305 | 99 |
| C07AG | Carvedilol · Labetalol | 99 | 38 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is APO-PROPRANOLOL called?
The same molecule, Propranolol, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| Inderal | Latin | Australia, Sweden |
| Inderal® | Latin | Sweden |
| Propranolol Medical Valley | Latin | Sweden |
| PROPRANOLOL-WGR | Latin | Australia |
| Prodorol | Latin | South Africa |
| Properal | Latin | Saudi Arabia |
| Propranolol Accord | Latin | Sweden |
| Propranolol Ebb | Latin | Sweden |
| AVLOCARDYL | Latin | Morocco |
| AVLOCAN | Latin | Morocco |
| AVLOCARDYL LP | Latin | Morocco |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
This DIN is dormant — it holds a Health Canada authorization but is not currently being marketed in Canada, so it cannot simply be ordered from Canadian stock. Where a patient need exists, supply may be possible through exceptional importation or the Special Access Programme, subject to Health Canada's requirements and the prescriber's application. Nexara can advise on the route and on marketed alternatives.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.