APO PEN VK 300 MG / 5 ML
PENICILLIN V POTASSIUM : 300 MG / 5 ML · DIN 00642231 · APOTEX INC
Health Canada status: CANCELLED POST MARKET
What is APO PEN VK?
APO PEN VK 300 MG / 5 ML contains PENICILLIN V POTASSIUM : 300 MG / 5 ML. It is listed in the Health Canada Drug Product Database under DIN 00642231, held by APOTEX INC, supplied as POWDER FOR SOLUTION for ORAL administration. Health Canada currently lists it as cancelled post market, status dated 24-Oct-2024. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is APO PEN VK used for?
Mild to moderately severe infections caused by penicillin V sensitive microorganisms including streptococcal pharyngitis, staphylococcal infection without bacteremia and pneumococcal infections. Therapy should be guided by bacteriologic sensitivity tests and clinical response. For prophylaxis following rheumatic fever and/or chorea. To prevent bacterial endocarditis in patients with congenital and/or rheumatic heart lesions before dental procedures, minor upper respiratory tract surgery or instrumentation. For the prevention of bacteremia following tooth extraction.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
Product details and regulatory record
| DIN | 00642231 |
|---|---|
| Brand name | APO PEN VK |
| Generic / active ingredient | PENICILLIN V POTASSIUM : 300 MG / 5 ML |
| Manufacturer | APOTEX INC |
| Strength | 300 MG / 5 ML |
| Dosage form | POWDER FOR SOLUTION |
| Route of administration | ORAL |
| Schedule | Prescription |
| ATC code | J01CE02 PHENOXYMETHYLPENICILLIN |
| AHFS class | 08:12.16.04 |
| Biosimilar | No |
| Health Canada status | CANCELLED POST MARKET |
| Status date | 24-Oct-2024 |
| Original market date | 1985-12-31 00:00:00 |
How is it administered?
Adults: 200,000-500,000 units every 6-8 hours. Children <12: 25,000-90,000 units/kg in 3-6 divided doses. Duration varies by infection (e.g., 10 days for streptococcal).
Included because it drives pack selection and wastage. Consult the monograph.
How is it stored and handled?
Tablets: Store at 15°C to 30°C. Powder for suspension: Store at room temperature 15°C to 30°C. Suspension: Store the oral suspension for 14 days under refrigeration.
How is it supplied?
Tablets: Available in bottles of 100, 500 and 1,000 tablets. Powder For Suspension: Each strength is available in 60 and 100 ml bottles.
Contraindications
History of penicillin or cephalosporin allergy; against beta lactamase producing organisms; active treatment of syphilis, subacute bacterial endocarditis, diphtheria, or gas gangrene.
Warnings and precautions
Serious/fatal hypersensitivity (anaphylaxis) reported. Severe Cutaneous Adverse Reactions (SCAR) like SJS/TEN. Use caution in patients with allergies or asthma. Not for severe illness.
What can be used instead?
Other Canadian products sharing ATC code J01CE02 PHENOXYMETHYLPENICILLIN. 1 of 21 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.
| Product | Strength | Form | Manufacturer | Health Canada status | DIN |
|---|---|---|---|---|---|
| PEN-VK | 300 MG | TABLET | AA PHARMA INC | MARKETED | DIN 00642215 |
| APO PEN VK | 125 MG / 5 ML | POWDER FOR SOLUTION | APOTEX INC | CANCELLED POST MARKET | DIN 00642223 |
| LEDERCILLIN VK - TAB 400000 UNIT | 400000 UNIT | TABLET | WYETH-AYERST CANADA INC. | CANCELLED POST MARKET | DIN 02169975 |
| LEDERCILLIN VK - TAB 800000UNITS | 800000 UNIT | TABLET | WYETH-AYERST CANADA INC. | CANCELLED POST MARKET | DIN 02169983 |
| LEDERCILLIN VK TAB 400000UNIT | 250 MG | TABLET | LEDERLE CYANAMID CANADA INC. | CANCELLED POST MARKET | DIN 00014982 |
| LEDERCILLIN VK TAB 800000UNIT | 500 MG | TABLET | LEDERLE CYANAMID CANADA INC. | CANCELLED POST MARKET | DIN 00127760 |
| NADOPEN V 200 | 40000 UNIT | POWDER FOR SOLUTION | LIOH INC. | CANCELLED POST MARKET | DIN 00018635 |
| NADOPEN V 400 | 80000 UNIT | POWDER FOR SOLUTION | LIOH INC. | CANCELLED POST MARKET | DIN 00251631 |
| NADOPEN V TAB 500000IU | 500000 UNIT | TABLET | LIOH INC. | CANCELLED POST MARKET | DIN 00018740 |
| NOVO-PEN VK SYR 500000/5ML | 300 MG / 5 ML | POWDER FOR SOLUTION | NOVOPHARM LIMITED | CANCELLED POST MARKET | DIN 00391603 |
Who else supplies PHENOXYMETHYLPENICILLIN worldwide?
Nexara tracks national medicine registries and published price lists across multiple markets. PHENOXYMETHYLPENICILLIN appears in 90 registered pack listings across 9 markets, published on 8 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.
Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.