SODIUM CHLORIDE, INHALATION SOLUTION, U.S.P. (0.45% NACL) 0.45 % — DIN 00612081
SODIUM CHLORIDE : 0.45 % · MEDEX, INC. · SOLUTION · wholesale supply in Canada
Health Canada status: CANCELLED POST MARKET
What is SODIUM CHLORIDE, INHALATION SOLUTION, U.S.P. (0.45% NACL)?
SODIUM CHLORIDE, INHALATION SOLUTION, U.S.P. (0.45% NACL) 0.45 % contains SODIUM CHLORIDE : 0.45 %. It is listed in the Health Canada Drug Product Database under DIN 00612081, held by MEDEX, INC., supplied as SOLUTION for INHALATION administration. Health Canada currently lists it as cancelled post market, status dated 26-Aug-2004. This Drug Identification Number is no longer authorized for sale in Canada, so Nexara does not supply it. The record is kept here because buyers still meet the number on old formularies, purchase orders and tender documents; Nexara can help identify an authorized alternative.
Is there a generic Various in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
7 holders have a Canadian DIN containing Various, across 17 DINs, of which 3 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| PENDOPHARM DIVISION OF PHARMASCIENCE INC | 3 | 3 | RHINARIS NASAL GEL, RHINARIS NASAL MIST, SECARIS | Sourceable in Canada |
| DEY PHARMA L.P. | 3 | 0 | DEY-PAK SODIUM CHLORIDE SOLUTION 0.45%, DEY-PAK SODIUM CHLORIDE SOLUTION 10%, DEY-PAK SODIUM CHLORIDE SOLUTION 3% | No marketed DIN |
| MEDEX, INC. | 3 | 0 | SODIUM CHLORIDE INHALATION SOLUTION U.S.P. (0.90% NACL), SODIUM CHLORIDE, INHALATION SOLUTION, U.S.P. (0.45% NACL), STERILE WATER FOR INHALATION U.S.P. | No marketed DIN |
| PHARMASCIENCE INC | 3 | 0 | LUBRICATING NASAL GEL, LUBRICATING NASAL MIST | No marketed DIN |
| AUTOMATIC LIQUID PACKAGING INC., HEALTHCARE PRODUCTS DIVISION | 2 | 0 | STERILE WATER, STERILE WATER FOR INHALATION USP 3ML | No marketed DIN |
| JAMIESON LABORATORIES LTD | 2 | 0 | RHINEDRINE LUBRICANT NASAL GEL, RHINEDRINE MOISTURIZING NASAL MIST -LIQ NAS | No marketed DIN |
| CARDINAL HEALTH MEDICAL PRODUCTS AND SERVICES | 1 | 0 | AIRLIFE STERILE WATER FOR INHALATION USP | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 0.45 % |
|---|---|
| Dosage form | SOLUTION |
| Route | INHALATION |
Pack detail is kept as a regulatory record. This DIN is no longer authorized for sale in Canada, so Nexara does not quote this pack.
Substance and classification
| Active substance | Various |
|---|---|
| ATC code | R01AX10 |
| AHFS class | 40:12.00 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 00612081 |
|---|---|
| DIN (unpadded, as printed on some documents) | 612081 |
| Brand name | SODIUM CHLORIDE, INHALATION SOLUTION, U.S.P. (0.45% NACL) |
| Generic / active ingredient | SODIUM CHLORIDE : 0.45 % |
| Market authorization holder | MEDEX, INC. |
| Health Canada schedule | Ethical |
| ATC code | R01AX10 |
| ATC anatomical main group | R — Respiratory system |
| ATC therapeutic subgroup | R01AX |
| Current status | CANCELLED POST MARKET |
| Status date | 26-Aug-2004 |
| Original market date | 1986-12-31 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
3 of 17 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| RHINARIS NASAL GEL | 15 % | GEL | PENDOPHARM DIVISION OF PHARMASCIENCE INC | MARKETED | 02352699 |
| RHINARIS NASAL MIST | 5 % | SPRAY, METERED DOSE | PENDOPHARM DIVISION OF PHARMASCIENCE INC | MARKETED | 02354551 |
| SECARIS | 15 % | GEL | PENDOPHARM DIVISION OF PHARMASCIENCE INC | MARKETED | 00551805 |
| AIRLIFE STERILE WATER FOR INHALATION USP | 100 % | LIQUID | CARDINAL HEALTH MEDICAL PRODUCTS AND SERVICES | CANCELLED POST MARKET | 00790117 |
| DEY-PAK SODIUM CHLORIDE SOLUTION 0.45% | .45 % | SOLUTION | DEY PHARMA L.P. | CANCELLED POST MARKET | 02058227 |
| DEY-PAK SODIUM CHLORIDE SOLUTION 10% | 10 % | SOLUTION | DEY PHARMA L.P. | CANCELLED POST MARKET | 02058243 |
| DEY-PAK SODIUM CHLORIDE SOLUTION 3% | 3 % | SOLUTION | DEY PHARMA L.P. | CANCELLED POST MARKET | 02058251 |
| LUBRICATING NASAL GEL | 15 % | GEL | PHARMASCIENCE INC | DORMANT | 02220806 |
| LUBRICATING NASAL MIST | 20 % | METERED-DOSE AEROSOL | PHARMASCIENCE INC | CANCELLED POST MARKET | 00551813 |
| LUBRICATING NASAL MIST | 15 % | METERED-DOSE AEROSOL | PHARMASCIENCE INC | CANCELLED POST MARKET | 00732230 |
2 · Same class — other molecules in ATC R01AX
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Various | AIRLIFE STERILE WATER FOR INHALATION USP · DEY-PAK SODIUM CHLORIDE SOLUTION 0.45% · DEY-PAK SODIUM CHLORIDE SOLUTION 10% · DEY-PAK SODIUM CHLORIDE SOLUTION 3% · +12 more | 17 | 3 | Yes |
| Ipratropium Bromide | ATROVENT NASAL SPRAY · DOM-IPRATROPIUM · IPRATROPIUM · IPRAVENT · +1 more | 7 | 1 | Yes |
| Combinations | AIRLIFE MODUDOSE 0.45% SODIUM CHLORIDE SOLUTION · AIRLIFE SODIUM CHLORIDE INHALATION SOLUTION USP (0.45%) · AIRLIFE SODIUM CHLORIDE INHALATION SOLUTION USP (0.9%) · BACTERIOSTATIC NACL DILUENT FOR INHALATION · +13 more | 18 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC R01A
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| R01AD | Beclomethasone · Budesonide · Ciclesonide · Flunisolide · Fluticasone · +5 more | 55 | 24 |
| R01AA | Ephedrine · Oxymetazoline · Phenylephrine · Xylometazoline | 76 | 18 |
| R01AB | Ephedrine · Naphazoline · Oxymetazoline · Phenylephrine | 12 | 1 |
| R01AC | Cromoglicic Acid · Levocabastine | 6 | 0 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
Can this still be bought in Canada?
No. This Drug Identification Number is cancelled post market in Health Canada's Drug Product Database, so the product is no longer authorized for sale in Canada and Nexara does not supply it. This page is kept as a regulatory record.
If you are looking for a current equivalent, the alternatives above list every product sharing this therapeutic class, with the marketed ones first. Ask us to source an alternative
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.