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NITROUS OXIDE 98 % — DIN 00334758

NITROUS OXIDE : 98 % · MATHESON GAS PRODUCTS CANADA INC. · GAS · wholesale supply in Canada

Health Canada status: CANCELLED POST MARKET

What is NITROUS OXIDE?

NITROUS OXIDE 98 % contains NITROUS OXIDE : 98 %. It is listed in the Health Canada Drug Product Database under DIN 00334758, held by MATHESON GAS PRODUCTS CANADA INC., supplied as GAS for INHALATION administration. Health Canada currently lists it as cancelled post market, status dated 24-Dec-1997. This Drug Identification Number is no longer authorized for sale in Canada, so Nexara does not supply it. The record is kept here because buyers still meet the number on old formularies, purchase orders and tender documents; Nexara can help identify an authorized alternative.

Is there a generic Nitrous Oxide in Canada, and who makes it?

Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.

6 holders have a Canadian DIN containing Nitrous Oxide, across 6 DINs, of which 3 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.

Market authorization holderDINsMarketedBrand namesPosition
AIR LIQUIDE CANADA INC.11NITROUS OXIDE 100%Sourceable in Canada
LINDE CANADA INC.11NITROUS OXIDE USPSourceable in Canada
MESSER CANADA INC.11NITROUS OXIDE U.S.P.Sourceable in Canada
AIR PRODUCTS CANADA LTD/LTÉE.10NITROUS OXIDE 99%No marketed DIN
LIQUID CARBONIC INC.10NITROUS OXIDE USPNo marketed DIN
MATHESON GAS PRODUCTS CANADA INC.10NITROUS OXIDENo marketed DIN

Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.

How is it supplied and stored?

Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.

Strength on the label98 %
Dosage formGAS
RouteINHALATION

Pack detail is kept as a regulatory record. This DIN is no longer authorized for sale in Canada, so Nexara does not quote this pack.

Substance and classification

Active substanceNitrous Oxide
ATC codeN01AX13
Biosimilar biologicNo

Health Canada record and identifiers

The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.

DIN (8-digit, as used in ordering)00334758
DIN (unpadded, as printed on some documents)334758
Brand nameNITROUS OXIDE
Generic / active ingredientNITROUS OXIDE : 98 %
Market authorization holderMATHESON GAS PRODUCTS CANADA INC.
Health Canada scheduleEthical
ATC codeN01AX13
ATC anatomical main groupN — Nervous system
ATC therapeutic subgroupN01AX
Current statusCANCELLED POST MARKET
Status date24-Dec-1997
Status sourceLive Health Canada DPD sync

Verify on the primary sources

Health Canada DPD record

What can be used instead?

Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.

1 · Same molecule, other Canadian presentations

3 of 6 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.

ProductStrengthFormHolderHealth Canada statusDIN
NITROUS OXIDE 100%100 %GASAIR LIQUIDE CANADA INC.MARKETED00572845
NITROUS OXIDE U.S.P.99 %GASMESSER CANADA INC.MARKETED02154811
NITROUS OXIDE USP99 %GASLINDE CANADA INC.MARKETED02014467
NITROUS OXIDE 99%99 %GASAIR PRODUCTS CANADA LTD/LTÉE.CANCELLED POST MARKET00591637
NITROUS OXIDE USP99 %GASLIQUID CARBONIC INC.CANCELLED POST MARKET00684678

2 · Same class — other molecules in ATC N01AX

MoleculeCanadian brandsDINsMarketedSourceable
KetamineKETALAR · KETAMINE HYDROCHLORIDE INJECTION SDZ · KETAMINE HYDROCHLORIDE INJECTION USP · KETAMINE HYDROCHLORIDE INJECTION, USP · +1 more137Yes
PropofolDIPRIVAN 1% · PROPOFOL · PROPOFOL INJECTION · PROPOFOL-II INJECTION · +1 more114Yes
Nitrous OxideNITROUS OXIDE · NITROUS OXIDE 100% · NITROUS OXIDE 99% · NITROUS OXIDE U.S.P. · +1 more63Yes
Nitrous Oxide,CombinationsALNOX GAS · LIQUI-MED ANALGESIC GAS · MEOPA · NITROUS OXIDE IN OXYGEN43Yes
EtomidateETOMIDATE INJECTION USP · ETOMIDATE INJECTION, USP · TOMVI32Yes
DroperidolINAPSINE INJ 2.5MG/ML10Not in Canada

A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.

3 · Adjacent classes in ATC N01A

ATC subgroupMoleculesDINsMarketed
N01AHAlfentanil · Anileridine · Fentanyl · Fentanyl, Combinations · Remifentanil · +1 more3312
N01ABDesflurane · Enflurane · Halothane · Isoflurane · Sevoflurane196
N01AFMethohexital · Thiopental60

Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.

Can this still be bought in Canada?

No. This Drug Identification Number is cancelled post market in Health Canada's Drug Product Database, so the product is no longer authorized for sale in Canada and Nexara does not supply it. This page is kept as a regulatory record.

If you are looking for a current equivalent, the alternatives above list every product sharing this therapeutic class, with the marketed ones first. Ask us to source an alternative

Ordering questions

Who can buy this from Nexara?

Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.

Is there a minimum order?

Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.

What is the lead time?

Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.

Why is there no price on this page?

Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.

Can Nexara supply this for a clinical trial?

Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.

Sources and disclaimer

Product data sourced from the Health Canada Drug Product Database. Health Canada status reconciled against the live DPD sync. Last reviewed 10 Sep 2026.

Nothing on this page is medical advice. Nexara Health is a licensed wholesale distributor and supplies licensed entities only; consumer orders are routed to a partner pharmacy. Alternatives tables describe supply, not clinical equivalence.

Health Canada Drug Product Database (DPD), DIN 00334758. Last reviewed 2026-09-10. Nexara Health is a licensed wholesaler and supplies licensed entities only; consumer orders are routed to a partner pharmacy.