DEMO-CINEOL ENFANTS/CHILDREN 185 MG — DIN 00319724
EUCALYPTOL : 185 MG CAMPHOR : 20 MG GUAIACOL : 90 MG GUAIACOL CARBONATE : 100 MG · LABORATOIRES CONFAB INC · SUPPOSITORY · wholesale supply in Canada
Health Canada status: MARKETED
What is DEMO-CINEOL ENFANTS/CHILDREN?
DEMO-CINEOL ENFANTS/CHILDREN 185 MG contains EUCALYPTOL : 185 MG CAMPHOR : 20 MG GUAIACOL : 90 MG GUAIACOL CARBONATE : 100 MG. It is listed in the Health Canada Drug Product Database under DIN 00319724, held by LABORATOIRES CONFAB INC, supplied as SUPPOSITORY for RECTAL administration. Health Canada currently lists it as marketed, status dated 19-Jul-2022. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
How much does Combinations cost around the world?
Combinations is listed on 4 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Czechia publishes a max producer price (ex-factory); Hungary publishes a producer price (ex-factory); Iceland publishes a max wholesale. Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| Hungary | producer price (ex-factory) | 5 | 5 | HUF███.██ |
| Czechia | max producer price (ex-factory) | 1 | 1 | CZK███.██ |
| Iceland | max wholesale | 1 | 1 | ISK███.██ |
| Luxembourg | reimbursement | 1 | 1 | EUR███.██ |
8 pack listings across 8 brand entries and 4 price bases, refreshed 05 Sep 2026. Ranges span every Combinations pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Combinations in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
31 holders have a Canadian DIN containing Combinations, across 42 DINs, of which 4 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| LABORATOIRES CONFAB INC | 4 | 4 | CREO-RECTAL ADULTES/ADULTS, CREO-RECTAL ENFANTS/CHILDREN, DEMO-CINEOL ADULTES/ADULTS, DEMO-CINEOL ENFANTS/CHILDREN | Sourceable in Canada |
| NUTRIBON (1986) INC. | 4 | 0 | PULMOREX EXPECTORANT LIQ, PULMOSIRUM DECONGESTIONNANT SIROP, PULMOSIRUM EXPECTORANT SYRUP, PULMOSIRUM PLUS EXPECTORANT | No marketed DIN |
| NOVARTIS CONSUMER HEALTH CANADA INC. | 2 | 0 | TRIAMINIC CHEST AND NASAL CONGESTION, TRIAMINIC EXPECTORANT SYR | No marketed DIN |
| PRODUITS FRANCAIS LABS INC. | 2 | 0 | BRONCHO TUSS ADULT, BRONCHO TUSS INFANT | No marketed DIN |
| PURDUE PHARMA | 2 | 0 | ENTEX LA | No marketed DIN |
| RHONE-POULENC RORER CONSUMER INC. | 2 | 0 | PHENERGAN EXPECTORANT SYR, PHENERGAN VC EXPECTORANT SYR | No marketed DIN |
| ROUGIER PHARMA DIVISION OF RATIOPHARM INC | 2 | 0 | BISMUTAL ADULTS, I.D.M. SOLUTION | No marketed DIN |
| D.C. LABS LIMITED | 1 | 0 | BRONCHOZONE COUGH SYRUP CERTIFIED | No marketed DIN |
| GLAXOSMITHKLINE CONSUMER HEALTHCARE ULC | 1 | 0 | NON DROWSY REGULAR STRENGTH CONTAC COLD CHEST CONGESTION | No marketed DIN |
| HERBES UNIVERSELLES INC. | 1 | 0 | BRONCO ASMOL | No marketed DIN |
| J L MATHIEU CIE LTEE | 1 | 0 | MATHIEU COUGH SYRUP | No marketed DIN |
| JAMP PHARMA CORPORATION | 1 | 0 | JAMP-SUPPOSITORIES CHILDREN | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 185 MG |
|---|---|
| Dosage form | SUPPOSITORY |
| Route | RECTAL |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Combinations |
|---|---|
| ATC code | R05CA10 |
| AHFS class | 48:16.00 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 00319724 |
|---|---|
| DIN (unpadded, as printed on some documents) | 319724 |
| Brand name | DEMO-CINEOL ENFANTS/CHILDREN |
| Generic / active ingredient | EUCALYPTOL : 185 MG CAMPHOR : 20 MG GUAIACOL : 90 MG GUAIACOL CARBONATE : 100 MG |
| Market authorization holder | LABORATOIRES CONFAB INC |
| Health Canada schedule | NON-PRESCRIPTION DRUGS |
| ATC code | R05CA10 |
| ATC anatomical main group | R — Respiratory system |
| ATC therapeutic subgroup | R05CA |
| Current status | MARKETED |
| Status date | 19-Jul-2022 |
| Original market date | 1977-12-31 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
4 of 42 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| CREO-RECTAL ADULTES/ADULTS | 1.5 MG | SUPPOSITORY | LABORATOIRES CONFAB INC | MARKETED | 00299561 |
| CREO-RECTAL ENFANTS/CHILDREN | 200 MG | SUPPOSITORY | LABORATOIRES CONFAB INC | MARKETED | 00299596 |
| DEMO-CINEOL ADULTES/ADULTS | 200 MG | SUPPOSITORY | LABORATOIRES CONFAB INC | MARKETED | 00319716 |
| ALSIDRINE LIQ | 7 MG | LIQUID | ALSI CIE LTEE | CANCELLED POST MARKET | 00429058 |
| BABYS OWN COUGH SYR | 1 G / 100 ML | LIQUID | G.T. FULFORD PHARMACEUTICALS | CANCELLED POST MARKET | 00395390 |
| BISMUTAL ADULTS | 150 MG | SUPPOSITORY | ROUGIER PHARMA DIVISION OF RATIOPHARM INC | CANCELLED POST MARKET | 00535168 |
| BRONCH EZE | 4 MG / 5 ML | SYRUP | PHARMAVITE LABORATORIES (1987) INC. | CANCELLED POST MARKET | 00484709 |
| BRONCHEX COUGH SYRUP | 93.67 MG / 5 ML | SYRUP | HILARY'S DISTIBUTION LTD. | CANCELLED POST MARKET | 00756865 |
| BRONCHIAL COUGH SYR | 45 MG | SYRUP | THERALAB INC. | CANCELLED POST MARKET | 00525499 |
| BRONCHO TUSS ADULT | 60 MG | SUPPOSITORY | PRODUITS FRANCAIS LABS INC. | CANCELLED POST MARKET | 00540897 |
2 · Same class — other molecules in ATC R05CA
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Guaifenesin | AIR-POWER · BALMINIL EXPECTORANT · BALMINIL EXPECTORANT (SUCROSE FREE) · BALMINIL EXPECTORANT LIQ 100MG/5ML · +50 more | 59 | 10 | Yes |
| Combinations | ALSIDRINE LIQ · BABYS OWN COUGH SYR · BISMUTAL ADULTS · BRONCH EZE · +37 more | 42 | 4 | Yes |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC R05C
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| R05CB | Acetylcysteine · Dornase Alfa (Desoxyribonuclease) | 11 | 4 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is DEMO-CINEOL ENFANTS/CHILDREN called?
The same molecule, Combinations, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| Ekyflogyl | Latin | Iceland |
| OTIPAX | Latin | Czechia |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.