CORTISONE ACETATE 25 MG — DIN 00280437
CORTISONE ACETATE : 25 MG · BAUSCH HEALTH, CANADA INC. · TABLET · wholesale supply in Canada
Health Canada status: MARKETED
What is CORTISONE ACETATE?
CORTISONE ACETATE 25 MG contains CORTISONE ACETATE : 25 MG. It is listed in the Health Canada Drug Product Database under DIN 00280437, held by BAUSCH HEALTH, CANADA INC., supplied as TABLET for ORAL administration. Health Canada currently lists it as marketed, status dated 17-Jun-2019. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is CORTISONE ACETATE used for?
Management of disorders responsive to adrenocortical hormone therapy: endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, respiratory, hematological, neoplastic, and edematous states.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How much does Cortisone cost around the world?
Cortisone is listed on 2 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Australia publishes a ex-manufacturer; Italy publishes a prezzo al pubblico (classe A). Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| Australia | ex-manufacturer | 1 | 4 | AUD███.██ |
| Italy | prezzo al pubblico (classe A) | 1 | 1 | EUR███.██ |
5 pack listings across 2 brand entries and 2 price bases, refreshed 08 Sep 2026. Ranges span every Cortisone pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Cortisone in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
2 holders have a Canadian DIN containing Cortisone, across 4 DINs, of which 1 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| BAUSCH HEALTH, CANADA INC. | 1 | 1 | CORTISONE ACETATE | Sourceable in Canada |
| MERCK FROSST CANADA & CIE, MERCK FROSST CANADA & CO. | 3 | 0 | CORTONE SUS 50MG/ML, CORTONE TAB 25MG, CORTONE TAB 5MG | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 25 MG |
|---|---|
| Dosage form | TABLET |
| Route | ORAL |
| Pack configuration (monograph) | Bottles of 100 tablets. |
| Storage | Not explicitly stated in the provided text. |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Cortisone |
|---|---|
| ATC code | H02AB10 |
| AHFS class | 28:36.08 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 00280437 |
|---|---|
| DIN (unpadded, as printed on some documents) | 280437 |
| Brand name | CORTISONE ACETATE |
| Generic / active ingredient | CORTISONE ACETATE : 25 MG |
| Market authorization holder | BAUSCH HEALTH, CANADA INC. |
| Health Canada schedule | Prescription |
| ATC code | H02AB10 |
| ATC anatomical main group | H — Systemic hormonal preparations |
| ATC therapeutic subgroup | H02AB |
| Current status | MARKETED |
| Status date | 17-Jun-2019 |
| Original market date | 1973-12-31 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
How is it administered?
Varies by condition: 25-300 mg/day. Chronic: start 25-50 mg/day. Acute: 75-150 mg/day. Life-threatening: 125-300 mg/day in 4 divided doses. Adjust to minimum effective dose.
Included because it drives pack selection and wastage. Consult the monograph.
Contraindications
Tuberculosis (active/healed), ocular herpes simplex, acute psychoses. Relative: peptic ulcer, renal insufficiency, hypertension, diabetes, infections (fungal/viral), CHF.
Warnings and precautions
May mask infection; avoid abrupt cessation; prolonged use causes adrenal cortex reduction; may cause hyperacidity/peptic ulcer; may aggravate diabetes; monitor intraocular pressure in glaucoma.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
1 of 4 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| CORTONE SUS 50MG/ML | 50 MG | SUSPENSION | MERCK FROSST CANADA & CIE, MERCK FROSST CANADA & CO. | CANCELLED POST MARKET | 00016241 |
| CORTONE TAB 25MG | 25 MG | TABLET | MERCK FROSST CANADA & CIE, MERCK FROSST CANADA & CO. | CANCELLED POST MARKET | 00016446 |
| CORTONE TAB 5MG | 5 MG | TABLET | MERCK FROSST CANADA & CIE, MERCK FROSST CANADA & CO. | CANCELLED POST MARKET | 00016438 |
2 · Same class — other molecules in ATC H02AB
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Dexamethasone | APO-DEXAMETHASONE · DECADRON PHOSPHATE INJ 4MG/ML · DECADRON TAB 0.5MG · DECADRON TAB 4MG · +24 more | 42 | 13 | Yes |
| Methylprednisolone | DEPO-MEDROL · MEDROL · METHYLPREDNISOLONE ACETATE INJECTABLE SUSPENSION USP · METHYLPREDNISOLONE ACETATE INJECTABLE SUSPENSION USP -(80MG/ML WITH PRESERVATIVE) · +7 more | 34 | 13 | Yes |
| Hydrocortisone | A-HYDROCORT INJ 1000MG/8ML · A-HYDROCORT INJ 100MG/2ML · A-HYDROCORT INJ 250MG/2ML · A-HYDROCORT INJ 500MG/4ML · +6 more | 18 | 8 | Yes |
| Prednisone | ALTI-PREDNISONE TAB 5MG · APO PREDNISONE TAB 1MG USP · APO PREDNISONE TAB 50MG · APO PREDNISONE TAB 5MG · +11 more | 19 | 5 | Yes |
| Triamcinolone | ARISTOCORT - SYR ORL 0.4MG/ML · ARISTOCORT - TAB 4MG · ARISTOCORT FORTE - LIQ IA IM ISY 40MG/ML · ARISTOCORT FORTE INJ 40MG/ML · +15 more | 21 | 3 | Yes |
| Betamethasone | BETAJECT · BETNESOL TAB 0.5MG · BETNESOL TABLETS · CELESTONE REPETABS 1MG · +2 more | 6 | 1 | Yes |
| Prednisolone | NOVO-PREDNISOLONE 5MG · PEDIAPRED · PEDIAPRED - LIQ 6.7MG/5ML · PMS-PREDNISOLONE | 4 | 1 | Yes |
| Cortisone | CORTISONE ACETATE · CORTONE SUS 50MG/ML · CORTONE TAB 25MG · CORTONE TAB 5MG | 4 | 1 | Yes |
| Prednisone, Combinations | METRETON TAB | 1 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC H02A
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| H02AA | Fludrocortisone | 3 | 2 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is CORTISONE ACETATE called?
Also recorded in Canada as: cortisone acetate 25 MG Oral Tablet (US), 1.85% HYDROCORTISONE ACETATE - 1.15% PRAMOXINE HCI CREAM (US), ANTI-ITCH VULVA CREAM 1 HYDROCORTISONE ACETATE (US), COLISTIN SULFATE, NEOMYCIN SULFATE, THONZONIUM BROMIDE AND HYDROCORTISONE ACETATE (US), COLISTIN SULFATE, NEOMYCIN SULFATE, THONZONIUM BROMIDE, AND HYDROCORTISONE ACETATE (US), FLUDROCORTISONE ACETATE (US).
The same molecule, Cortisone, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| Cortate | Latin | Australia |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.