M-PILOCARPINE 5 MG
PILOCARPINE HYDROCHLORIDE : 5 MG · DIN 02496119 · MANTRA PHARMA INC
Health Canada status: MARKETED
What is M-PILOCARPINE?
M-PILOCARPINE 5 MG contains PILOCARPINE HYDROCHLORIDE : 5 MG. It is listed in the Health Canada Drug Product Database under DIN 02496119, held by MANTRA PHARMA INC, supplied as TABLET for ORAL administration. Health Canada currently lists it as marketed, status dated 14-Jun-2021. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is M-PILOCARPINE used for?
Treatment of xerostomia (dry mouth) symptoms due to salivary gland hypofunction from radiotherapy for head and neck cancer, and symptoms of xerostomia and xerophthalmia in Sjögren's syndrome.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
Product details and regulatory record
| DIN | 02496119 |
|---|---|
| Brand name | M-PILOCARPINE |
| Generic / active ingredient | PILOCARPINE HYDROCHLORIDE : 5 MG |
| Manufacturer | MANTRA PHARMA INC |
| Strength | 5 MG |
| Dosage form | TABLET |
| Route of administration | ORAL |
| Schedule | Prescription |
| ATC code | N07AX01 PILOCARPINE |
| AHFS class | 12:04.00 |
| Biosimilar | No |
| Health Canada status | MARKETED |
| Status date | 14-Jun-2021 |
| Original market date | 2020-05-12 00:00:00 |
How is it administered?
Initial dose: 5 mg 3-4 times daily. May titrate up to 10 mg per dose, not to exceed 30 mg/day. Tablets should be swallowed whole, not chewed or bitten. May be taken with or without food.
Included because it drives pack selection and wastage. Consult the monograph.
How is it stored and handled?
Not specified in the provided text excerpt (refer to full monograph).
How is it supplied?
Not explicitly detailed in the provided text (mentions bottles of tablets in general pharmaceutical context but specific sizes not listed in this excerpt).
Contraindications
Uncontrolled asthma; when miosis is undesirable (e.g., acute iritis, narrow-angle glaucoma); known sensitivity to pilocarpine or any tablet excipients.
Warnings and precautions
Caution in patients with significant cardiovascular disease, asthma, COPD, biliary tract disease, peptic ulcers, or cognitive/psychiatric disturbances. May cause blurred vision/impaired depth perception.
What can be used instead?
Other Canadian products sharing ATC code N07AX01 PILOCARPINE. 3 of 5 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.
| Product | Strength | Form | Manufacturer | Health Canada status | DIN |
|---|---|---|---|---|---|
| JAMP PILOCARPINE | 5 MG | TABLET | JAMP PHARMA CORPORATION | MARKETED | DIN 02509571 |
| SALAGEN | 5 MG | TABLET | AMDIPHARM LIMITED | MARKETED | DIN 02216345 |
| PILOCARPINE HYDROCHLORIDE TABLETS | 5 MG | TABLET | METHAPHARM INC | APPROVED | DIN 02506580 |
| PILOCARPINE HYDROCHLORIDE TABLETS, USP | 5 MG | TABLET | STERIMAX INC | DORMANT | DIN 02402483 |
Who else supplies PILOCARPINE worldwide?
Nexara tracks national medicine registries and published price lists across multiple markets. PILOCARPINE appears in 36 registered pack listings across 8 markets, published on 7 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.
Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.