Diphenhydramine Hydrochloride — products, DINs, and Canadian availability

This page lists Health Canada–registered pharmaceutical products whose active ingredient list includes Diphenhydramine Hydrochloride. We track 120 distinct Drug Identification Numbers (DINs) for this molecule, of which 30 are currently in marketed status. Across those registrations there are 39 manufacturers or marketing authorization holders, 15 dosage forms, and 19 distinct strength presentations.

Procurement teams normally arrive here for one of three reasons: a specific brand is unavailable and an equivalent registration is needed; a clinical protocol requires a comparator containing Diphenhydramine Hydrochloride in a defined strength; or a pharmacy needs to know which manufacturers still hold an active Canadian registration before committing to a substitution. The table below answers the first question directly. For the second and third, Nexara Health can confirm live availability, remaining shelf life, and landed cost from Canadian stock or from any of more than 40 regulated international source markets.

Registration status is not the same as availability. A product can hold marketed status in the Drug Product Database and still be on allocation, discontinued by the holder, or unavailable in the pack size a hospital needs. Where a Diphenhydramine Hydrochloride product is in shortage, our Canadian drug shortage tracker carries the reported status, the reason where the manufacturer has published one, and the marketed alternatives sharing the same active ingredient.

Dosage forms and strengths recorded for Diphenhydramine Hydrochloride

Dosage forms: Tablet, Kit; Capsule, Capsule, Elixir, Liquid, Cream, Solution, Tablet (Chewable), Spray, Syrup, Strip, Gel. Strengths: 25 MG, 200 MG, 50 MG, 220 MG, 12.5 MG, 2 %, 500 MG, 10 MG, 2.0 %, 3.33 MG, 325 MG, 5 MG, 160 MG, 6.25 MG.

Manufacturers and marketing authorization holders

LABORATOIRES TRIANON INC., GLAXOSMITHKLINE CONSUMER HEALTHCARE ULC, HALEON CANADA ULC, ANGITA PHARMA INC., BAYER INC, TEVA CANADA LIMITED, TECHNILAB PHARMA INC., VALEANT CANADA LP / VALEANT CANADA S.E.C., ACCUDIAL PHARMACEUTICAL INC, TANTA PHARMACEUTICALS INC, HERBION CANADA, G&W LABORATORIES INC., CELLCHEM PHARMACEUTICALS INC., GENVION CORPORATION, PHARMASCIENCE INC, LSL MEDPLUS INC, VITA HEALTH PRODUCTS INC, PERRIGO INTERNATIONAL, SIGMA LIFE SCIENCES INC., CATALENT ONTARIO LIMITED, and others.

Registered products containing Diphenhydramine Hydrochloride

Sourcing Diphenhydramine Hydrochloride through a licensed wholesaler

Nexara Health imports and distributes under Health Canada Drug Establishment Licence #3-002896. For Diphenhydramine Hydrochloride we can quote Canadian-marketed presentations, equivalent registrations from the EU, UK, US, Switzerland, Australia, and Japan where the Canadian presentation is unavailable, and comparator-grade supply with Certificate of Analysis, batch and expiry records, and full chain of custody for clinical trial use. Cold-chain presentations ship under GDP conditions with continuous temperature monitoring.

Related pages

• Browse all active ingredients
• Canadian drug shortage tracker
• Alternatives to Diphenhydramine Hydrochloride
• Comparator sourcing for clinical trials