IBAVYR 400 MG — DIN 02425890
RIBAVIRIN : 400 MG · PENDOPHARM DIVISION OF PHARMASCIENCE INC · TABLET · wholesale supply in Canada
Health Canada status: DORMANT
What is IBAVYR?
IBAVYR 400 MG contains RIBAVIRIN : 400 MG. It is listed in the Health Canada Drug Product Database under DIN 02425890, held by PENDOPHARM DIVISION OF PHARMASCIENCE INC, supplied as TABLET for ORAL administration. Health Canada currently lists it as dormant, status dated 31-Jul-2023. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A). This DIN is not currently being marketed in Canada, so it is sourced to order where a compliant route exists rather than held in stock.
What is IBAVYR used for?
In combination with other agents for the treatment of chronic hepatitis C (CHC) in adults. Not for monotherapy.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How much does Ribavirin cost around the world?
Ribavirin is listed on 5 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Iceland publishes a max wholesale; Saudi Arabia publishes a public; South Africa publishes a single exit price. Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| Saudi Arabia | public | 3 | 4 | SAR███.██ |
| United Kingdom | hospital | 1 | 1 | GBP███.██ |
| Iceland | max wholesale | 1 | 1 | ISK███.██ |
| United States | acquisition | 1 | 1 | USD███.██ |
| South Africa | single exit price | 1 | 1 | ZAR███.██ |
8 pack listings across 7 brand entries and 5 price bases, refreshed 03 Sep 2026. Ranges span every Ribavirin pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Ribavirin in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
4 holders have a Canadian DIN containing Ribavirin, across 8 DINs, of which 1 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| BAUSCH HEALTH, CANADA INC. | 1 | 1 | VIRAZOLE | Sourceable in Canada |
| ABBVIE CORPORATION | 3 | 0 | MODERIBA | No marketed DIN |
| PENDOPHARM DIVISION OF PHARMASCIENCE INC | 3 | 0 | IBAVYR | No marketed DIN |
| VIRATEK INC. | 1 | 0 | VIRAZOLE PWS 6GM/VIAL | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 400 MG |
|---|---|
| Dosage form | TABLET |
| Route | ORAL |
| Pack configuration (monograph) | Bottles of 100 tablets. |
| Storage | Not explicitly detailed in provided text (Section 11 not fully visible), but typically 15-30°C for tablets. |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Ribavirin |
|---|---|
| ATC code | J05AP01 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02425890 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2425890 |
| Brand name | IBAVYR |
| Generic / active ingredient | RIBAVIRIN : 400 MG |
| Market authorization holder | PENDOPHARM DIVISION OF PHARMASCIENCE INC |
| Health Canada schedule | Prescription |
| ATC code | J05AP01 |
| ATC anatomical main group | J — Anti-infectives for systemic use |
| ATC therapeutic subgroup | J05AP |
| Current status | DORMANT |
| Status date | 31-Jul-2023 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
How is it administered?
Administered orally in two divided doses with food. Usual dose 800-1200 mg daily (up to 1400 mg) depending on weight and combination agent. Refer to specific agent monographs for duration.
Included because it drives pack selection and wastage. Consult the monograph.
Contraindications
Hypersensitivity; pregnancy or male partners of pregnant women; hemoglobinopathies (e.g., thalassemia, sickle-cell anemia); coadministration with didanosine.
Warnings and precautions
Not for monotherapy. Hemolytic anemia may worsen cardiac disease (risk of MI). Significant teratogenic and embryocidal effects; avoid pregnancy during and 6 months after treatment.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
1 of 8 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| VIRAZOLE | 6 G | AEROSOL ; POWDER FOR SOLUTION | BAUSCH HEALTH, CANADA INC. | MARKETED | 02170140 |
| IBAVYR | 200 MG | TABLET | PENDOPHARM DIVISION OF PHARMASCIENCE INC | DORMANT | 02439212 |
| IBAVYR | 600 MG | TABLET | PENDOPHARM DIVISION OF PHARMASCIENCE INC | DORMANT | 02425904 |
| MODERIBA | 200 MG | TABLET | ABBVIE CORPORATION | CANCELLED POST MARKET | 02436396 |
| MODERIBA | 400 MG | TABLET | ABBVIE CORPORATION | CANCELLED POST MARKET | 02436418 |
| MODERIBA | 600 MG | TABLET | ABBVIE CORPORATION | CANCELLED POST MARKET | 02436426 |
| VIRAZOLE PWS 6GM/VIAL | 6 G | AEROSOL ; POWDER FOR SOLUTION | VIRATEK INC. | CANCELLED POST MARKET | 00704008 |
2 · Same class — other molecules in ATC J05AP
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Glecaprevir And Pibrentasvir | MAVIRET | 2 | 2 | Yes |
| Ribavirin | IBAVYR · MODERIBA · VIRAZOLE · VIRAZOLE PWS 6GM/VIAL | 8 | 1 | Yes |
| Sofosbuvir | SOVALDI | 1 | 1 | Yes |
| Sofosbuvir And Ledipasvir | HARVONI | 1 | 1 | Yes |
| Sofosbuvir, Velpatasvir And Voxilaprevir | VOSEVI | 1 | 1 | Yes |
| Daclatasvir | DAKLINZA | 2 | 0 | Not in Canada |
| Asunaprevir | SUNVEPRA | 1 | 0 | Not in Canada |
| Telaprevir | INCIVEK | 1 | 0 | Not in Canada |
| Boceprevir | VICTRELIS | 1 | 0 | Not in Canada |
| Dasabuvir, Ombitasvir, Paritaprevir And Ritonavir | HOLKIRA PAK | 1 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC J05A
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| J05AB | Acyclovir · Brincidofovir · Cidofovir · Famciclovir · Ganciclovir · +3 more | 143 | 55 |
| J05AR | Antivirals For Treatment Of Hiv Infections, Combinations · Atanazavir And Cobicistat · Darunavir And Cobicistat · Dolutegravir And Rilpivirine · Emtricitabine And Tenofovir Alafenamide · +16 more | 56 | 39 |
| J05AF | Abacavir · Adefovir Dipivoxil · Didanosine · Emtricitabine · Entecavir · +7 more | 71 | 39 |
| J05AH | Neuraminidase Inhibitors · Oseltamivir · Zanamivir | 33 | 16 |
| J05AX | Baloxavir Marboxil · Bulevirtide · Enfuvirtide · Fostemsavir · Inosine Pranobex · +5 more | 19 | 14 |
| J05AE | Amprenavir · Atazanavir · Darunavir · Fosamprenavir · Indinavir · +5 more | 75 | 14 |
| J05AG | Delavirdine · Doravirine · Efavirenz · Etravirine · Nevirapine · +1 more | 22 | 10 |
| J05AJ | Cabotegravir · Dolutegravir · Elvitegravir · Raltegravir | 12 | 6 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is IBAVYR called?
The same molecule, Ribavirin, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| RIAVIRIN | Latin | Saudi Arabia |
| Copegus | Latin | South Africa |
| Ribavirin | Latin | Iceland |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
This DIN is dormant — it holds a Health Canada authorization but is not currently being marketed in Canada, so it cannot simply be ordered from Canadian stock. Where a patient need exists, supply may be possible through exceptional importation or the Special Access Programme, subject to Health Canada's requirements and the prescriber's application. Nexara can advise on the route and on marketed alternatives.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.