SIBBORAN 300 MG — DIN 02543338
LANDIOLOL HYDROCHLORIDE : 300 MG · TRIMEDIC THERAPEUTICS INC. · POWDER FOR SOLUTION · wholesale supply in Canada
Health Canada status: DORMANT
What is SIBBORAN?
SIBBORAN 300 MG contains LANDIOLOL HYDROCHLORIDE : 300 MG. It is listed in the Health Canada Drug Product Database under DIN 02543338, held by TRIMEDIC THERAPEUTICS INC., supplied as POWDER FOR SOLUTION for INTRAVENOUS administration. Health Canada currently lists it as dormant, status dated 05-Jun-2026. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A). This DIN is not currently being marketed in Canada, so it is sourced to order where a compliant route exists rather than held in stock.
How much does Landiolol cost around the world?
Landiolol is listed on 3 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Greece publishes a producer price (ex-factory); Iceland publishes a max wholesale; Romania publishes a max producer price. Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| Iceland | max wholesale | 1 | 2 | ISK███.██ |
| Romania | max producer price | 2 | 2 | RON███.██ |
| Greece | producer price (ex-factory) | 1 | 1 | EUR███.██ |
5 pack listings across 4 brand entries and 3 price bases, refreshed 03 Sep 2026. Ranges span every Landiolol pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 300 MG |
|---|---|
| Dosage form | POWDER FOR SOLUTION |
| Route | INTRAVENOUS |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Landiolol |
|---|---|
| ATC code | C07AB14 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02543338 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2543338 |
| Brand name | SIBBORAN |
| Generic / active ingredient | LANDIOLOL HYDROCHLORIDE : 300 MG |
| Market authorization holder | TRIMEDIC THERAPEUTICS INC. |
| Health Canada schedule | Prescription |
| ATC code | C07AB14 |
| ATC anatomical main group | C — Cardiovascular system |
| ATC therapeutic subgroup | C07AB |
| Current status | DORMANT |
| Status date | 05-Jun-2026 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
2 · Same class — other molecules in ATC C07AB
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Metoprolol | AA-METOPROLOL SR · AG-METOPROLOL-L · APO-METOPROLOL · APO-METOPROLOL (TYPE L) · +44 more | 103 | 30 | Yes |
| Atenolol | ACT ATENOLOL · AG-ATENOLOL · APO-ATENOL TAB 100MG · APO-ATENOL TAB 50MG · +35 more | 87 | 28 | Yes |
| Bisoprolol | AG-BISOPROLOL · APO-BISOPROLOL · AVA-BISOPROLOL · BISOPROLOL · +19 more | 52 | 24 | Yes |
| Nebivolol | APO-NEBIVOLOL · BYSTOLIC · JAMP NEBIVOLOL · PRZ-NEBIVOLOL | 13 | 9 | Yes |
| Acebutolol | ACEBUTOLOL · ACEBUTOLOL - 400 · ACEBUTOLOL-100 · ACEBUTOLOL-200 · +20 more | 44 | 6 | Yes |
| Esmolol | BREVIBLOC INJECTION 10MG/ML · BREVIBLOC INJECTION 250MG/ML · BREVIBLOC LIQ IV 10MG/ML · BREVIBLOC LIQ IV 250MG/ML · +1 more | 5 | 2 | Yes |
| Landiolol | SIBBORAN | 1 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC C07A
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| C07AG | Carvedilol · Labetalol | 99 | 38 |
| C07AA | Nadolol · Oxprenolol · Pindolol · Propranolol · Sotalol · +1 more | 177 | 27 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is SIBBORAN called?
The same molecule, Landiolol, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| Rapibloc | Latin | Iceland |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
This DIN is dormant — it holds a Health Canada authorization but is not currently being marketed in Canada, so it cannot simply be ordered from Canadian stock. Where a patient need exists, supply may be possible through exceptional importation or the Special Access Programme, subject to Health Canada's requirements and the prescriber's application. Nexara can advise on the route and on marketed alternatives.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.