IRINOTECAN HYDROCHLORIDE INJECTION 500 MG / 25 ML — DIN 02528789
IRINOTECAN HYDROCHLORIDE : 500 MG / 25 ML · EUGIA PHARMA INC. · SOLUTION · wholesale supply in Canada
Health Canada status: MARKETED
What is IRINOTECAN HYDROCHLORIDE INJECTION?
IRINOTECAN HYDROCHLORIDE INJECTION 500 MG / 25 ML contains IRINOTECAN HYDROCHLORIDE : 500 MG / 25 ML. It is listed in the Health Canada Drug Product Database under DIN 02528789, held by EUGIA PHARMA INC., supplied as SOLUTION for INTRAVENOUS administration. Health Canada currently lists it as marketed, status dated 28-Feb-2024. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
How much does Irinotecan cost around the world?
Irinotecan is listed on 11 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Australia publishes a ex-manufacturer; Greece publishes a producer price (ex-factory); Hungary publishes a producer price (ex-factory). Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| Italy | ex-factory (classe H) | 27 | 32 | EUR███.██ |
| Romania | max producer price | 5 | 20 | RON███.██ |
| Greece | producer price (ex-factory) | 17 | 17 | EUR███.██ |
| Saudi Arabia | public | 9 | 16 | SAR███.██ |
| Morocco | PPV (public price) | 5 | 9 | MAD███.██ |
| Australia | ex-manufacturer | 4 | 8 | AUD███.██ |
| United Kingdom | hospital | 8 | 8 | GBP███.██ |
| South Africa | single exit price | 4 | 4 | ZAR███.██ |
| Iceland | max wholesale | 1 | 2 | ISK███.██ |
| Hungary | producer price (ex-factory) | 1 | 1 | HUF███.██ |
| Lebanon | public price (USD, Decision 119/1) | 1 | 1 | USD███.██ |
118 pack listings across 82 brand entries and 10 price bases, refreshed 08 Sep 2026. Ranges span every Irinotecan pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Irinotecan in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
10 holders have a Canadian DIN containing Irinotecan, across 18 DINs, of which 8 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| AURO PHARMA INC | 4 | 2 | IRINOTECAN HYDROCHLORIDE INJECTION | Sourceable in Canada |
| EUGIA PHARMA INC. | 4 | 2 | IRINOTECAN HYDROCHLORIDE INJECTION | Sourceable in Canada |
| PFIZER CANADA ULC | 3 | 1 | CAMPTOSAR, IRINOTECAN, IRINOTECAN HYDROCHLORIDE INJECTION USP | Sourceable in Canada |
| ACCORD HEALTHCARE INC | 1 | 1 | IRINOTECAN HYDROCHLORIDE INJECTION USP | Sourceable in Canada |
| GENERIC MEDICAL PARTNERS INC | 1 | 1 | IRINOTECAN HYDROCHLORIDE INJECTION, USP | Sourceable in Canada |
| TEVA CANADA LIMITED | 1 | 1 | IRINOTECAN FOR INJECTION | Sourceable in Canada |
| FRESENIUS KABI CANADA LTD | 1 | 0 | IRINOTECAN HYDROCHLORIDE TRIHYDRATE FOR INJECTION | No marketed DIN |
| IPSEN BIOPHARMACEUTICALS CANADA INC | 1 | 0 | ONIVYDE | No marketed DIN |
| SANDOZ CANADA INCORPORATED | 1 | 0 | IRINOTECAN HYDROCHLORIDE TRIHYDRATE INJECTION | No marketed DIN |
| TELIP, LLC, A SUBSIDIARY OF TELIGENT, INC. | 1 | 0 | IRINOTECAN HYDROCHLORIDE INJECTION | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 500 MG / 25 ML |
|---|---|
| Dosage form | SOLUTION |
| Route | INTRAVENOUS |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation, because this listing covers more than one of them.
Substance and classification
| Active substance | Irinotecan |
|---|---|
| ATC code | L01CE02 |
| AHFS class | 10:00.00 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02528789 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2528789 |
| Brand name | IRINOTECAN HYDROCHLORIDE INJECTION |
| Generic / active ingredient | IRINOTECAN HYDROCHLORIDE : 500 MG / 25 ML |
| Market authorization holder | EUGIA PHARMA INC. |
| Health Canada schedule | Prescription |
| ATC code | L01CE02 |
| ATC anatomical main group | L — Antineoplastic and immunomodulating agents |
| ATC therapeutic subgroup | L01CE |
| Current status | MARKETED |
| Status date | 28-Feb-2024 |
| Original market date | 2024-02-28 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
Is Irinotecan in shortage in Canada?
A Canadian shortage report is on file for a product containing this molecule: Anticipated — reported by PFIZER CANADA ULC, last seen 04 Sep 2026. A shortage on one presentation does not always affect every DIN of the molecule — the alternatives below list what else is marketed in Canada. Nexara can confirm current availability and identify substitutions or import options where permitted.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
8 of 18 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| IRINOTECAN FOR INJECTION | 20 MG | SOLUTION | TEVA CANADA LIMITED | MARKETED | 02312409 |
| IRINOTECAN HYDROCHLORIDE INJECTION | 100 MG / 5 ML | SOLUTION | AURO PHARMA INC | MARKETED | 02501279 |
| IRINOTECAN HYDROCHLORIDE INJECTION | 100 MG / 5 ML | SOLUTION | EUGIA PHARMA INC. | MARKETED | 02528800 |
| IRINOTECAN HYDROCHLORIDE INJECTION | 500 MG / 25 ML | SOLUTION | AURO PHARMA INC | MARKETED | 02501295 |
| IRINOTECAN HYDROCHLORIDE INJECTION USP | 20 MG | SOLUTION | PFIZER CANADA ULC | MARKETED | 02258218 |
| IRINOTECAN HYDROCHLORIDE INJECTION USP | 20 MG | SOLUTION | ACCORD HEALTHCARE INC | MARKETED | 02357585 |
| IRINOTECAN HYDROCHLORIDE INJECTION, USP | 20 MG | SOLUTION | GENERIC MEDICAL PARTNERS INC | MARKETED | 02452421 |
| CAMPTOSAR | 20 MG | SOLUTION | PFIZER CANADA ULC | CANCELLED POST MARKET | 02231622 |
| IRINOTECAN | 20 MG | SOLUTION | PFIZER CANADA ULC | CANCELLED POST MARKET | 02410419 |
| IRINOTECAN HYDROCHLORIDE INJECTION | 20 MG | SOLUTION | TELIP, LLC, A SUBSIDIARY OF TELIGENT, INC. | CANCELLED POST MARKET | 02412187 |
2 · Same class — other molecules in ATC L01CE
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Irinotecan | CAMPTOSAR · IRINOTECAN · IRINOTECAN FOR INJECTION · IRINOTECAN HYDROCHLORIDE INJECTION · +5 more | 18 | 8 | Yes |
| Topotecan | HYCAMTIN · MYLAN-TOPOTECAN HYDROCHLORIDE FOR INJECTION · PMS-TOPOTECAN · TEVA-TOPOTECAN · +3 more | 14 | 4 | Yes |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC L01C
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| L01CD | Cabazitaxel · Docetaxel · Paclitaxel | 41 | 13 |
| L01CA | Vinblastine · Vincristine · Vindesine · Vinorelbine | 22 | 7 |
| L01CB | Etoposide · Teniposide | 14 | 3 |
| L01CX | Trabectedin | 1 | 1 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is IRINOTECAN HYDROCHLORIDE INJECTION called?
The same molecule, Irinotecan, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| Irinotecan Accord | Latin | Australia, Iceland |
| IRINOTECAN COOPER | Latin | Morocco |
| CAMPTO | Latin | Morocco |
| IRINOTECAN BAXTER | Latin | Australia |
| IRINOTECAN EUGIA | Latin | Australia |
| Irinotecan Irem | Latin | Australia |
| Irinotecan BOS | Latin | Saudi Arabia |
| IRINOTECAN HYDROCHLORIDE | Latin | Lebanon |
| Onivyde pegylated liposomal | Latin | Saudi Arabia |
| TECAN | Latin | Morocco |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.