MAR-CLONIDINE 0.025 MG — DIN 02524198
CLONIDINE HYDROCHLORIDE : 0.025 MG · MARCAN PHARMACEUTICALS INC · TABLET · wholesale supply in Canada
Health Canada status: MARKETED
What is MAR-CLONIDINE?
MAR-CLONIDINE 0.025 MG contains CLONIDINE HYDROCHLORIDE : 0.025 MG. It is listed in the Health Canada Drug Product Database under DIN 02524198, held by MARCAN PHARMACEUTICALS INC, supplied as TABLET for ORAL administration. Health Canada currently lists it as marketed, status dated 11-Apr-2022. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is MAR-CLONIDINE used for?
Relief of menopausal flushing in patients for whom hormonal replacement therapy is either unnecessary or not desirable.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How much does Clonidine cost around the world?
Clonidine is listed on 7 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Australia publishes a ex-manufacturer; Greece publishes a producer price (ex-factory); Iceland publishes a max wholesale. Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| United States | acquisition | 6 | 83 | USD███.██ |
| Australia | ex-manufacturer | 4 | 8 | AUD███.██ |
| Iceland | max wholesale | 6 | 8 | ISK███.██ |
| South Africa | single exit price | 2 | 3 | ZAR███.██ |
| United Kingdom | hospital | 2 | 2 | GBP███.██ |
| Greece | producer price (ex-factory) | 1 | 1 | EUR███.██ |
| Morocco | PPV (public price) | 1 | 1 | MAD███.██ |
106 pack listings across 22 brand entries and 7 price bases, refreshed 08 Sep 2026. Ranges span every Clonidine pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Clonidine in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
12 holders have a Canadian DIN containing Clonidine, across 31 DINs, of which 14 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| TEVA CANADA LIMITED | 6 | 3 | NTP-CLONIDINE, TEVA-CLONIDINE | Sourceable in Canada |
| MINT PHARMACEUTICALS INC | 3 | 3 | MINT-CLONIDINE | Sourceable in Canada |
| SANDOZ CANADA INCORPORATED | 3 | 3 | SANDOZ CLONIDINE | Sourceable in Canada |
| SIVEM PHARMACEUTICALS ULC | 3 | 3 | CLONIDINE | Sourceable in Canada |
| JAMP PHARMA CORPORATION | 1 | 1 | JAMP CLONIDINE | Sourceable in Canada |
| MARCAN PHARMACEUTICALS INC | 1 | 1 | MAR-CLONIDINE | Sourceable in Canada |
| APOTEX INC | 3 | 0 | APO-CLONIDINE, APO-CLONIDINE TAB 0.1MG, APO-CLONIDINE TAB 0.2MG | No marketed DIN |
| SANIS HEALTH INC | 3 | 0 | CLONIDINE | No marketed DIN |
| BOEHRINGER INGELHEIM (CANADA) LTD LTEE | 2 | 0 | CATAPRES TAB 0.1MG, CATAPRES TAB 0.2MG | No marketed DIN |
| DOMINION PHARMACAL | 2 | 0 | DOM-CLONIDINE | No marketed DIN |
| NU-PHARM INC | 2 | 0 | NU-CLONIDINE TAB 0.1MG, NU-CLONIDINE TAB 0.2MG | No marketed DIN |
| PRO DOC LIMITEE | 2 | 0 | CLONIDINE 0.1, CLONIDINE HCL TAB 0.2MG | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 0.025 MG |
|---|---|
| Dosage form | TABLET |
| Route | ORAL |
| Pack configuration (monograph) | Bottles of 100 tablets. |
| Storage | Store between 15°C - 30°C. Protect from moisture. |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Clonidine |
|---|---|
| ATC code | C02AC01 |
| AHFS class | 24:08.16 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02524198 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2524198 |
| Brand name | MAR-CLONIDINE |
| Generic / active ingredient | CLONIDINE HYDROCHLORIDE : 0.025 MG |
| Market authorization holder | MARCAN PHARMACEUTICALS INC |
| Health Canada schedule | Prescription |
| ATC code | C02AC01 |
| ATC anatomical main group | C — Cardiovascular system |
| ATC therapeutic subgroup | C02AC |
| Current status | MARKETED |
| Status date | 11-Apr-2022 |
| Original market date | 2022-04-11 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
How is it administered?
Recommended dose for menopausal flushing: 0.05 mg twice daily. If no remission after 2-4 weeks, discontinue. Discontinue treatment at 3-6 month intervals for re-evaluation.
Included because it drives pack selection and wastage. Consult the monograph.
Contraindications
Hypersensitivity to clonidine; severe bradyarrhythmia (sick sinus syndrome, 2nd/3rd degree AV block); rare hereditary conditions incompatible with excipients (e.g., galactose intolerance).
Warnings and precautions
Do not confuse with higher strengths (0.1/0.2 mg). Abrupt withdrawal can cause catecholamine excess. Caution in patients with coronary insufficiency, recent MI, or Raynaud's disease.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
14 of 31 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| CLONIDINE | 0.025 MG | TABLET | SIVEM PHARMACEUTICALS ULC | MARKETED | 02540061 |
| CLONIDINE | 0.1 MG | TABLET | SIVEM PHARMACEUTICALS ULC | MARKETED | 02538490 |
| CLONIDINE | 0.2 MG | TABLET | SIVEM PHARMACEUTICALS ULC | MARKETED | 02538504 |
| JAMP CLONIDINE | 0.025 MG | TABLET | JAMP PHARMA CORPORATION | MARKETED | 02528207 |
| MINT-CLONIDINE | 0.1 MG | TABLET | MINT PHARMACEUTICALS INC | MARKETED | 02462192 |
| MINT-CLONIDINE | 0.025 MG | TABLET | MINT PHARMACEUTICALS INC | MARKETED | 02534738 |
| MINT-CLONIDINE | 0.2 MG | TABLET | MINT PHARMACEUTICALS INC | MARKETED | 02462206 |
| SANDOZ CLONIDINE | 0.025 MG | TABLET | SANDOZ CANADA INCORPORATED | MARKETED | 02516217 |
| SANDOZ CLONIDINE | 0.2 MG | TABLET | SANDOZ CANADA INCORPORATED | MARKETED | 02515792 |
| SANDOZ CLONIDINE | 0.1 MG | TABLET | SANDOZ CANADA INCORPORATED | MARKETED | 02515784 |
2 · Same class — other molecules in ATC C02AC
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Guanfacine | AG-GUANFACINE XR · APO-GUANFACINE XR · INTUNIV XR · JAMP GUANFACINE XR · +1 more | 19 | 19 | Yes |
| Clonidine | APO-CLONIDINE · APO-CLONIDINE TAB 0.1MG · APO-CLONIDINE TAB 0.2MG · CATAPRES TAB 0.1MG · +13 more | 31 | 14 | Yes |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC C02A
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| C02AB | Methyldopa (Levorotatory) · Methyldopa (Racemic) | 23 | 3 |
| C02AA | Reserpine | 2 | 0 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is MAR-CLONIDINE called?
The same molecule, Clonidine, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| APO-Clonidine | Latin | Australia |
| Catapres | Latin | Australia |
| Catapresan | Latin | Iceland |
| Clonidine Lupin | Latin | Australia |
| Menograine | Latin | South Africa |
| Catapresan (Distica) | Latin | Iceland |
| CATAPRESSAN | Latin | Morocco |
| Clonidin Ratiopharm | Latin | Iceland |
| Clonidine Hcl | Latin | Iceland |
| Dixarit | Latin | South Africa |
| Paracefan | Latin | Iceland |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.