VYNDAMAX 61 MG — DIN 02517841
TAFAMIDIS 61 MG · PFIZER CANADA ULC · Capsule · wholesale supply in Canada
Health Canada status: MARKETED
What is VYNDAMAX?
VYNDAMAX 61 MG contains TAFAMIDIS 61 MG. It is listed in the Health Canada Drug Product Database under DIN 02517841, held by PFIZER CANADA ULC, supplied as Capsule for Oral administration. Health Canada currently lists it as marketed, status dated 15-Sep-2021. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is VYNDAMAX used for?
VYNDAMAX (tafamidis) is indicated for the treatment of adult patients with cardiomyopathy due to transthyretin-mediated amyloidosis (ATTR-CM), wild-type or hereditary, to reduce cardiovascular mortality and cardiovascular-related hospitalization.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How much does Tafamidis cost around the world?
Tafamidis is listed on 13 of the national price registers Nexara ingests. Each country publishes on a different basis, so figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Australia publishes a ex-manufacturer; Austria publishes a KVP (Kassenverkaufspreis); Bahrain publishes a retail (max). Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed |
|---|---|---|---|
| Luxembourg | reimbursement | 3 | 3 |
| Austria | KVP (Kassenverkaufspreis) | 2 | 2 |
| Greece | producer price (ex-factory) | 2 | 2 |
| Italy | ex-factory (classe H) | 2 | 2 |
| Romania | max producer price | 1 | 2 |
| United Arab Emirates | public | 1 | 1 |
| Australia | ex-manufacturer | 1 | 1 |
| Bahrain | retail (max) | 1 | 1 |
| Brazil | preco fabrica (ex-factory ceiling) | 1 | 1 |
| Czechia | max producer price (ex-factory) | 1 | 1 |
| Iceland | max wholesale | 1 | 1 |
| Saudi Arabia | public | 1 | 1 |
| Slovakia | categorised final price | 1 | 1 |
19 pack listings across 18 brand entries and 12 price bases, refreshed 08 Sep 2026. Ranges span every Tafamidis pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Tafamidis in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
Only one market authorization holder has a Canadian DIN containing Tafamidis — 2 DINs, of which 2 are currently marketed. There is no second Canadian source today, so a supply interruption on this holder has no domestic substitute at the same molecule.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| PFIZER CANADA ULC | 2 | 2 | VYNDAMAX, VYNDAQEL | Sourceable in Canada |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 61 MG |
|---|---|
| Dosage form | Capsule |
| Route | Oral |
| Pack configuration (monograph) | VYNDAMAX (tafamidis) 61 mg: reddish brown, opaque, oblong (approximately 21 mm) capsule with "VYN 61" printed in white. Thirty (30) capsules (one-month supply) supplied in a carton of 3 blister cards. Each blister card contains 10 capsules. |
| Storage | Store VYNDAMAX at room temperature 15°C to 25°C. Keep out of reach and sight of children. |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Tafamidis |
|---|---|
| ATC code | N07XX08 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02517841 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2517841 |
| Brand name | VYNDAMAX |
| Generic / active ingredient | TAFAMIDIS 61 MG |
| Market authorization holder | PFIZER CANADA ULC |
| Health Canada schedule | PRESCRIPTION |
| ATC code | N07XX08 |
| ATC anatomical main group | N — Nervous system |
| ATC therapeutic subgroup | N07XX |
| Current status | MARKETED |
| Status date | 15-Sep-2021 |
| Original market date | 2021-09-15 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
How is it administered?
The recommended dose of VYNDAMAX (tafamidis) is 61 mg tafamidis (administered as one 61-mg tafamidis capsule) orally once daily. The capsule(s) should be swallowed whole and not crushed or cut. VYNDAMAX may be taken with or without food. If a dose is missed, the patient should take the dose as soon as remembered. If it is almost time for the next dose, the patient should skip the missed dose and take the next dose at the regularly scheduled time. Do not double the dose. The dose may be reduced to one capsule of 20 mg VYNDAQEL (tafamidis meglumine) (equivalent to 12.2 mg of tafamidis) if not tolerated.
Included because it drives pack selection and wastage. Consult the monograph.
Contraindications
VYNDAMAX (tafamidis) is contraindicated in patients who are hypersensitive to this drug or to any ingredient in the formulation, including any non-medicinal ingredient, or component of the container.
Warnings and precautions
VYNDAMAX should not be used during pregnancy. Women of childbearing potential should use appropriate contraception when taking VYNDAMAX and continue to use contraception for one month after stopping treatment. VYNDAMAX is not recommended in organ transplant patients. VYNDAMAX has not been studied in patients with severe hepatic impairment and use is not recommended in these patients. Limited data are available in patients with severe renal impairment (creatinine clearance less than or equal to 30 mL/min). VYNDAMAX should not be used by nursing women.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
2 of 2 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| VYNDAQEL | 20 MG | CAPSULE | PFIZER CANADA ULC | MARKETED | 02495732 |
2 · Same class — other molecules in ATC N07XX
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Fampridine | APO-FAMPRIDINE · FAMPYRA · PMS-FAMPRIDINE · TARO-FAMPRIDINE | 4 | 3 | Yes |
| Tetrabenazine | APO-TETRABENAZINE · NITOMAN · PMS-TETRABENAZINE · TETRABENAZINE TABLETS | 4 | 3 | Yes |
| Riluzole | APO-RILUZOLE · MYLAN-RILUZOLE · RILUTEK | 3 | 3 | Yes |
| Amifampridine | FIRDAPSE · RUZURGI | 2 | 2 | Yes |
| Hydroxybutyric Acid | XYREM · XYWAV | 2 | 2 | Yes |
| Pitolisant | WAKIX | 2 | 2 | Yes |
| Tafamidis | VYNDAMAX · VYNDAQEL | 2 | 2 | Yes |
| Edaravone | RADICAVA | 2 | 1 | Yes |
| Trofinetide | DAYBUE | 1 | 1 | Yes |
| Eplontersen | WAINUA | 1 | 1 | Yes |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is VYNDAMAX called?
Also recorded in Canada as: tafamidis 61 MG Oral Capsule [Vyndamax] (US), tafamidis meglumine 20 MG Oral Capsule [Vyndaqel] (US), tafamidis 61 MG Oral Capsule (US), tafamidis meglumine 20 MG Oral Capsule (US), TAFAMIDIS (US), TAFAMIDIS MEGLUMINE (US), VYNDAQEL (GLOBAL), TAFAMIDIS (GLOBAL), TAFAMIDIS MEGLUMINE (GLOBAL), TAFAMIDIS (UK), TAFAMIDIS MEGLUMINE (JP).
The same molecule, Tafamidis, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| Vyndaqel | Latin | Czechia, Iceland, Romania |
| VYNKELLA | Latin | Brazil |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.