MAR-METHIMAZOLE 10 MG — DIN 02480115
METHIMAZOLE : 10 MG · MARCAN PHARMACEUTICALS INC · TABLET · wholesale supply in Canada
Health Canada status: MARKETED
What is MAR-METHIMAZOLE?
MAR-METHIMAZOLE 10 MG contains METHIMAZOLE : 10 MG. It is listed in the Health Canada Drug Product Database under DIN 02480115, held by MARCAN PHARMACEUTICALS INC, supplied as TABLET for ORAL administration. Health Canada currently lists it as marketed, status dated 19-Oct-2018. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is MAR-METHIMAZOLE used for?
Medical treatment of hyperthyroidism; preparation for subtotal thyroidectomy or radioactive iodine therapy; use when thyroidectomy is contraindicated or not advisable.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How much does Thiamazole cost around the world?
Thiamazole is listed on 5 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Austria publishes a KVP (Kassenverkaufspreis); Czechia publishes a max producer price (ex-factory); Greece publishes a producer price (ex-factory). Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| Luxembourg | reimbursement | 5 | 5 | EUR███.██ |
| Greece | producer price (ex-factory) | 3 | 3 | EUR███.██ |
| Iceland | max wholesale | 3 | 3 | ISK███.██ |
| Austria | KVP (Kassenverkaufspreis) | 1 | 2 | EUR███.██ |
| Czechia | max producer price (ex-factory) | 1 | 2 | CZK███.██ |
15 pack listings across 13 brand entries and 5 price bases, refreshed 05 Sep 2026. Ranges span every Thiamazole pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Thiamazole in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
8 holders have a Canadian DIN containing Thiamazole, across 14 DINs, of which 4 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| JAMP PHARMA CORPORATION | 2 | 2 | JAMP METHIMAZOLE | Sourceable in Canada |
| MARCAN PHARMACEUTICALS INC | 2 | 2 | MAR-METHIMAZOLE | Sourceable in Canada |
| ENDO OPERATIONS LTD. | 5 | 0 | METHIMAZOLE TABLETS USP, TAPAZOLE | No marketed DIN |
| APOTEX INC | 1 | 0 | APO-METHIMAZOLE | No marketed DIN |
| DOMINION PHARMACAL | 1 | 0 | DOM-METHIMAZOLE | No marketed DIN |
| PALADIN PHARMA INC. | 1 | 0 | TAPAZOLE | No marketed DIN |
| PHARMASCIENCE INC | 1 | 0 | PMS-METHIMAZOLE | No marketed DIN |
| PHARMEL INC | 1 | 0 | PHL-METHIMAZOLE | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 10 MG |
|---|---|
| Dosage form | TABLET |
| Route | ORAL |
| Pack configuration (monograph) | Bottles of 100 tablets. |
| Storage | Store at room temperature (15°C to 30°C). Protect from light. Keep tightly closed. |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Thiamazole |
|---|---|
| ATC code | H03BB02 |
| AHFS class | 68:36.08 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02480115 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2480115 |
| Brand name | MAR-METHIMAZOLE |
| Generic / active ingredient | METHIMAZOLE : 10 MG |
| Market authorization holder | MARCAN PHARMACEUTICALS INC |
| Health Canada schedule | Prescription |
| ATC code | H03BB02 |
| ATC anatomical main group | H — Systemic hormonal preparations |
| ATC therapeutic subgroup | H03BB |
| Current status | MARKETED |
| Status date | 19-Oct-2018 |
| Original market date | 2018-10-19 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
How is it administered?
Initial: 15-60 mg/day divided into 3 doses at 8-hour intervals. Maintenance: 5-15 mg daily. Administered orally. Wash hands after handling.
Included because it drives pack selection and wastage. Consult the monograph.
Contraindications
Hypersensitivity to methimazole or any ingredient; breastfeeding women; history of acute pancreatitis after administration of methimazole.
Warnings and precautions
Serious: Agranulocytosis and liver toxicity. Risk of vasculitis, hypothyroidism, and acute pancreatitis. Monitor liver function and complete blood count.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
4 of 14 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| JAMP METHIMAZOLE | 5 MG | TABLET | JAMP PHARMA CORPORATION | MARKETED | 02490625 |
| JAMP METHIMAZOLE | 10 MG | TABLET | JAMP PHARMA CORPORATION | MARKETED | 02490633 |
| MAR-METHIMAZOLE | 5 MG | TABLET | MARCAN PHARMACEUTICALS INC | MARKETED | 02480107 |
| APO-METHIMAZOLE | 5 MG | TABLET | APOTEX INC | DORMANT | 02258935 |
| DOM-METHIMAZOLE | 5 MG | TABLET | DOMINION PHARMACAL | CANCELLED PRE MARKET | 02265869 |
| METHIMAZOLE TABLETS USP | 20 MG | TABLET | ENDO OPERATIONS LTD. | CANCELLED PRE MARKET | 02489732 |
| METHIMAZOLE TABLETS USP | 5 MG | TABLET | ENDO OPERATIONS LTD. | CANCELLED PRE MARKET | 02489716 |
| METHIMAZOLE TABLETS USP | 10 MG | TABLET | ENDO OPERATIONS LTD. | CANCELLED PRE MARKET | 02489724 |
| PHL-METHIMAZOLE | 5 MG | TABLET | PHARMEL INC | CANCELLED PRE MARKET | 02265850 |
| PMS-METHIMAZOLE | 5 MG | TABLET | PHARMASCIENCE INC | CANCELLED POST MARKET | 02244323 |
2 · Same class — other molecules in ATC H03BB
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Thiamazole | APO-METHIMAZOLE · DOM-METHIMAZOLE · JAMP METHIMAZOLE · MAR-METHIMAZOLE · +4 more | 14 | 4 | Yes |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC H03B
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| H03BA | Propylthiouracil | 8 | 2 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is MAR-METHIMAZOLE called?
The same molecule, Thiamazole, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| THYROZOL | Latin | Czechia |
| Apelka Vet. | Latin | Iceland |
| Thiamazol | Latin | Iceland |
| Thiamazole Uni-Pharma | Latin | Iceland |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.