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PENTHROX 99.9 %

METHOXYFLURANE : 99.9 % · DIN 02474719 · ENDO OPERATIONS LTD.

Health Canada status: MARKETED

What is PENTHROX?

PENTHROX 99.9 % contains METHOXYFLURANE : 99.9 %. It is listed in the Health Canada Drug Product Database under DIN 02474719, held by ENDO OPERATIONS LTD., supplied as SOLUTION for INHALATION administration. Health Canada currently lists it as marketed, status dated 18-Aug-2026. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.

What is PENTHROX used for?

PENTHROX (methoxyflurane) is indicated for: short-term relief of moderate to severe acute pain, associated with trauma or interventional medical procedures, in conscious adult patients. Due to dose limitations of a treatment course of PENTHROX and the duration of associated pain relief, PENTHROX is not appropriate for providing relief of break-through pain in chronic pain conditions. PENTHROX is also not appropriate for relief of repetitive pain.

Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.

Product details and regulatory record

DIN02474719
Brand namePENTHROX
Generic / active ingredientMETHOXYFLURANE : 99.9 %
ManufacturerENDO OPERATIONS LTD.
Strength99.9 %
Dosage formSOLUTION
Route of administrationINHALATION
SchedulePrescription
ATC codeN02BG09 METHOXYFLURANE
BiosimilarNo
Health Canada statusMARKETED
Status date18-Aug-2026

How is it stored and handled?

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How is it supplied?

Combination pack with a single (3 mL) dose, one PENTHROX Inhaler and one AC Chamber. Single dose (3 mL) pack of 10.

What can be used instead?

Other Canadian products sharing ATC code N02BG09 METHOXYFLURANE. 2 of 2 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.

ProductStrengthFormManufacturerHealth Canada statusDIN
PENTHROX99.9 %KIT ; SOLUTIONENDO OPERATIONS LTD.MARKETEDDIN 02474727

Who else supplies METHOXYFLURANE worldwide?

Nexara tracks national medicine registries and published price lists across multiple markets. METHOXYFLURANE appears in 7 registered pack listings across 5 markets, published on 4 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.

Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.

How can I get it?

Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.

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Ordering questions

Who can buy this from Nexara?

Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.

Is there a minimum order?

Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.

What is the lead time?

Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.

Can Nexara supply this for a clinical trial?

Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.

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Health Canada Drug Product Database (DPD), DIN 02474719. Last reviewed 2026-09-08. Nexara Health is a licensed wholesaler and supplies licensed entities only; consumer orders are routed to a partner pharmacy.