ENTUZITY KWIKPEN 500 UNIT — DIN 02466864
INSULIN INJECTION HUMAN BIOSYNTHETIC : 500 UNIT · ELI LILLY CANADA INC · SOLUTION · wholesale supply in Canada
Health Canada status: MARKETED
What is ENTUZITY KWIKPEN?
ENTUZITY KWIKPEN 500 UNIT contains INSULIN INJECTION HUMAN BIOSYNTHETIC : 500 UNIT. It is listed in the Health Canada Drug Product Database under DIN 02466864, held by ELI LILLY CANADA INC, supplied as SOLUTION for SUBCUTANEOUS administration. Health Canada currently lists it as marketed, status dated 20-Oct-2017. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is ENTUZITY KWIKPEN used for?
ENTUZITY is a concentrated human insulin indicated to improve glycemic control in adults and children with diabetes mellitus requiring more than 200 units of insulin per day.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How much does Insulin (Human) cost around the world?
Insulin (Human) is listed on 3 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Greece publishes a producer price (ex-factory); Norway publishes a max AUP (pharmacy retail); South Africa publishes a single exit price. Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| Greece | producer price (ex-factory) | 41 | 41 | EUR███.██ |
| Norway | max AUP (pharmacy retail) | 5 | 6 | NOK███.██ |
| South Africa | single exit price | 1 | 2 | ZAR███.██ |
49 pack listings across 47 brand entries and 3 price bases, refreshed 07 Sep 2026. Ranges span every Insulin (Human) pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Insulin (Human) in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
3 holders have a Canadian DIN containing Insulin (Human), across 18 DINs, of which 4 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| ELI LILLY CANADA INC | 11 | 3 | ENTUZITY KWIKPEN, HUMULIN 10/90 CARTRIDGE, HUMULIN 10/90 INJ, HUMULIN 20/80 CARTRIDGE, HUMULIN 20/80 INJ, +6 more | Sourceable in Canada |
| NOVO NORDISK CANADA INC | 4 | 1 | NOVOLIN GE 30/70, NOVOLIN GE 30/70 PENFILL, NOVOLIN GE 40/60 PENFILL, NOVOLIN GE 50/50 PENFILL | Sourceable in Canada |
| NOVO NORDISK A/S | 3 | 0 | NOVOLIN GE 10/90 PENFILL INJ SUS, NOVOLIN GE 20/80 PENFILL INJ SUS, NOVOLINSET GE 30/70 INJ SUS | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 500 UNIT |
|---|---|
| Dosage form | SOLUTION |
| Route | SUBCUTANEOUS |
| Pack configuration (monograph) | null |
| Storage | null |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Insulin (Human) |
|---|---|
| ATC code | A10AD01 |
| AHFS class | 68:20.08 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02466864 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2466864 |
| Brand name | ENTUZITY KWIKPEN |
| Generic / active ingredient | INSULIN INJECTION HUMAN BIOSYNTHETIC : 500 UNIT |
| Market authorization holder | ELI LILLY CANADA INC |
| Health Canada schedule | Schedule D |
| ATC code | A10AD01 |
| ATC anatomical main group | A — Alimentary tract and metabolism |
| ATC therapeutic subgroup | A10AD |
| Current status | MARKETED |
| Status date | 20-Oct-2017 |
| Original market date | 2017-10-20 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
4 of 18 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| HUMULIN 30/70 (INSULIN HUMAN BIOSYNTH INJ) | 30 UNIT | SUSPENSION | ELI LILLY CANADA INC | MARKETED | 00795879 |
| HUMULIN 30/70 CARTRIDGE | 70 UNIT | SUSPENSION | ELI LILLY CANADA INC | MARKETED | 01959212 |
| NOVOLIN GE 30/70 | 30 UNIT | SUSPENSION | NOVO NORDISK CANADA INC | MARKETED | 02024217 |
| HUMULIN 10/90 CARTRIDGE | 90 UNIT | SUSPENSION | ELI LILLY CANADA INC | CANCELLED POST MARKET | 01962639 |
| HUMULIN 10/90 INJ | 10 UNIT | SUSPENSION | ELI LILLY CANADA INC | CANCELLED POST MARKET | 00889113 |
| HUMULIN 20/80 CARTRIDGE | 80 UNIT | SUSPENSION | ELI LILLY CANADA INC | CANCELLED POST MARKET | 01962655 |
| HUMULIN 20/80 INJ | 80 UNIT | SUSPENSION | ELI LILLY CANADA INC | CANCELLED POST MARKET | 00889105 |
| HUMULIN 40/60 CARTRIDGE | 40 UNIT | SUSPENSION | ELI LILLY CANADA INC | CANCELLED POST MARKET | 01962647 |
| HUMULIN 40/60 INJ | 40 UNIT | SUSPENSION | ELI LILLY CANADA INC | CANCELLED POST MARKET | 00889091 |
| HUMULIN 50/50 CARTRIDGE | 50 UNIT | SUSPENSION | ELI LILLY CANADA INC | CANCELLED POST MARKET | 01962663 |
2 · Same class — other molecules in ATC A10AD
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Insulin (Human) | ENTUZITY KWIKPEN · HUMULIN 10/90 CARTRIDGE · HUMULIN 10/90 INJ · HUMULIN 20/80 CARTRIDGE · +14 more | 18 | 4 | Yes |
| Insulin Lispro | HUMALOG MIX 25 (CARTRIDGE) · HUMALOG MIX 25 (KWIKPEN) · HUMALOG MIX 25 (PEN) · HUMALOG MIX 50 (CARTRIDGE) · +5 more | 11 | 4 | Yes |
| Insulin Aspart | NOVOMIX 30 · NOVOMIX 30 (FLEXPEN) | 2 | 1 | Yes |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC A10A
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| A10AB | Insulin (Beef) · Insulin (Human) · Insulin (Pork) · Insulin Aspart · Insulin Glulisine · +1 more | 40 | 24 |
| A10AE | Insulin (Human) · Insulin Degludec · Insulin Degludec And Liraglutide · Insulin Detemir · Insulin Glargine · +2 more | 23 | 15 |
| A10AC | Insulin (Human) · Insulin (Pork) | 13 | 5 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is ENTUZITY KWIKPEN called?
The same molecule, Insulin (Human), is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| Actrapid HM (ge) | Latin | South Africa |
| Insuman Rapid | Latin | Norway |
| Humulin NPH | Latin | Norway |
| Humulin NPH KwikPen | Latin | Norway |
| Insuman Infusat | Latin | Norway |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.